Results 1 to 10 of about 50,177 (203)
Poultry Science, 2021 : Histomoniasis, also commonly referred to as blackhead disease, is caused by the protozoan parasite Histomonas meleagridis. Since the removal of nitarsone in 2015, no approved prophylactics are available for mitigating histomoniasis.
L.C. Beer, B.M. Hargis, C.N. Vuong
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Aptamer-based nanotrains and nanoflowers as quinine delivery systems
International Journal of Pharmaceutics: X, 2023 In this study, we designed aptamer-based self-assemblies for the delivery of quinine. Two different architectures were designed by hybridizing quinine binding aptamers and aptamers targeting Plasmodium falciparum lactate dehydrogenase (PfLDH): nanotrains
Mengyuan Cao +10 more
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QUININE AS AN ABORTIFACIENT. [PDF]
The Lancet, 1919 n ...
Swayne, W. C., Russell, Edward
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Aversion to Quinine is Associated with Taste Sensation in Chicks
The Journal of Poultry Science, 2005 Quinine is known as a bitter compound for humans and also used in animal experiment. However, there is no evidence that animals share the same taste sensation of quinine with humans.
Hiroshi Ueda, Saori Kainou
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Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients
BMC Pharmacology and Toxicology, 2018 Background Recent studies indicate that inflammation may also affect CYP3A4 activity. Associations of CYP3A4-mediated metabolism of quinine, with inflammatory biomarkers were investigated in patients undergoing maintenance hemodialysis (HD).
Hadi Molanaei +7 more
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Structure Modification of Quinine on C-9 Hydroxyl Group via Esterification Reaction [PDF]
Journal of Pure and Applied Chemistry Research, 2020 Concept the role played by modified quinine in the asymmetric hydroxyl group inspired studies of modified quinine as chiral organic that lead to drug discovery development.
Teni Ernawati +2 more
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Effects of Quinine, Quinidine and Chloroquine on Human Muscle Nicotinic Acetylcholine Receptors
Frontiers in Pharmacology, 2018 The genus Cinchona is known for a range of alkaloids, such as quinine, quinidine, cinchonine, and cinchonidine. Cinchona bark has been used as an antimalarial agent for more than 400 years.
Günter Gisselmann +3 more
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Malaria Journal, 2012 Background The naturally fluorescent compound quinine has long been used to treat malaria infections. Although some evidence suggests that quinine acts in the parasite food vacuole, the mechanism of action of quinine has not yet been resolved.
Bohórquez Elaine B +2 more
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Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro
Frontiers in Pharmacology, 2019 Cytochrome P450 3A4 (CYP3A4) enzyme activity is known to show considerable ethnic heterogeneity and inter-individual differences, affecting the outcome of drug treatment.
Xiao-Yang Zhou +7 more
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CPT: Pharmacometrics & Systems Pharmacology, 2022 Patients with cerebral malaria with polymorphic Cytochrome P450 2C19 (CYP2C19) genotypes who receive concurrent treatment with quinine are at risk of inadequate or toxic therapeutic drug concentrations due to metabolic drug interactions.
Teerachat Sae‐heng +4 more
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