Results 31 to 40 of about 50,177 (203)
Ratiometric dipyrene imaging resolves monomer (M) and excimer (E) channels and computes pixel‐wise E/M maps within biomolecular condensates, yielding physicochemical fingerprints shaped by coupled polarity‐related solvation and microviscosity. These spatial fingerprints enable quantitative phenotyping of cellular states, exemplified by separation of ...
Koki Matsumoto +20 more
wiley +1 more source
Stimulation of Erythrocyte Cell Membrane Scrambling by Quinine
Background/Aims: The analkaloid drug quinine is utilized mainly for the chemoprophylaxis of malaria. The multiple side effects of quinine include hemolytic anemia and hemolytic uremic syndrome, disorders involving suicidal erythrocyte death or eryptosis,
Morena Mischitelli +4 more
doaj +1 more source
The (R)-(6-Methoxyquinolin-4-yl)[(1S,2S,4S,5R)-5-vinylquinuclidin-2-yl]methanol (quinine)-tetraphenylborate complex was synthesized by reacting sodium tetraphenyl borate with quinine in deionized water at room temperature through an ion-pair reaction ...
Tarek A. Yousef +5 more
doaj +1 more source
Drug-induced Immune thrombocytopenia (DIT) is a common complication of several medications, including commonly used antibiotics. The most widely studied DIT is caused by quinine. In DIT, antibodies predominantly bind to the platelet membrane glycoprotein
Zohra Ahmadi +3 more
doaj +1 more source
Asymmetric Synthesis of Quinine: A Landmark in Organic Synthesis
Ever since its isolation in 1820, Quinine has played a crucial role in the development of organic chemistry, the chemical industry and modern medicine.
Vijay Nair +2 more
doaj +1 more source
An assay was developed measuring the disruption of rosettes between Plasmodium falciparuminfected (trophozoites) and uninfected erythrocytes by the antimalarial drugs quinine, artemisinin mefloquine, primaquine, pyrimethamine, chloroquine and proguanil ...
JP Dean Goldring +2 more
doaj +1 more source
Synthesis and Biological Activity of Novel Polyazaheterocyclic Derivatives of Quinine
A synthetic methodology of the CuAAC “click” approach was exploited for the construction of 1,2-azolyltriazole quinine derivatives by the reaction of O-propargylquinine with azidomethyl-1,2-azoles in methanol.
Gulim K. Mukusheva +10 more
doaj +1 more source
Demethylation of Quinine Using Anhydrous Aluminium Trichloride
Quinine is a natural alkaloid having a methoxy group bound to quinoline ring and an allyl group bound to quinuclidine ring. Demethylation of quinine applying strong acid such as HBr or HI at high temperature was unsuccessful. The aim of this research was
Aiyi Asnawi +3 more
doaj +1 more source

