Results 31 to 40 of about 83,070 (278)
Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients
BMC Pharmacology and Toxicology, 2018 Background Recent studies indicate that inflammation may also affect CYP3A4 activity. Associations of CYP3A4-mediated metabolism of quinine, with inflammatory biomarkers were investigated in patients undergoing maintenance hemodialysis (HD).
Hadi Molanaei +7 more
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Science Translational Medicine, 2019 A cellular thermal shift assay (CETSA) protocol identifies and resolves antimalarial drug targets in P. falciparum. Defining drug targets in malaria Different classes of malaria drugs have been used for decades, even though the mechanisms of action have ...
J. Dziekan +9 more
semanticscholar +1 more source
QUININE AS AN ABORTIFACIENT. [PDF]
The Lancet, 1919 n ...
Swayne, W. C., Russell, Edward
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An operational comparative study of quinine and artesunate for the treatment of severe malaria in hospitals and health centres in the Democratic Republic of Congo : the MATIAS study [PDF]
, 2015 The Democratic Republic of the Congo (DRC) has the highest number of severe malaria cases in the world. In early 2012, the National Malaria Control Programme (NMCP) changed the policy for treating severe malaria in children and adults from injectable ...
Lengeler, Christian +12 more
core +1 more source
Malaria Journal, 2012 Background The naturally fluorescent compound quinine has long been used to treat malaria infections. Although some evidence suggests that quinine acts in the parasite food vacuole, the mechanism of action of quinine has not yet been resolved.
Bohórquez Elaine B +2 more
doaj +1 more source
Agronomy, 2021 This study presents a tracer technique based on the fluorescent properties of quinine to help on the visualization of shallow flows and allow a quantitative measurement of overland flow velocities.
João L. M. P. de Lima +5 more
doaj +1 more source
Glycemic effects of quinine infusion in healthy volunteers
BMC Research Notes, 2017 Background We aimed to quantify the glycemic effects of quinine in healthy individuals. Methods We evaluated the glycemic profile in response to 4 h infusion of 500 ml of 0.9% saline versus 5% glucose solution with and without quinine at therapeutic dose
Audrey Carine Njomatchoua +3 more
doaj +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2022 Patients with cerebral malaria with polymorphic Cytochrome P450 2C19 (CYP2C19) genotypes who receive concurrent treatment with quinine are at risk of inadequate or toxic therapeutic drug concentrations due to metabolic drug interactions.
Teerachat Sae‐heng +4 more
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JAMA: The Journal of the American Medical Association, 1905 In thirteen consecutive cases of pneumonia developing in the course of a recent epidemic of that disease among the Indian school children on this reservation, the patients were treated by large doses of quinin, according to the method advocated by Galbraith, 1 without mortality.
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JAMA: The Journal of the American Medical Association, 1906 Following the cases of pneumonia reported in Dr. Galbraith's article inThe JournalFeb. 10, 1906, I have had many other cases, in all of which I have treated the patients according to Dr. Galbraith's method, but with a very much better result. Pneumonia is a very prevalent disease in Nogales and vicinity.
openaire +4 more sources