Results 51 to 60 of about 50,177 (203)

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin   +6 more
wiley   +1 more source

Detection, quantification, and investigation of the red blood cell partitioning of cryptolepine hydrochloride [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2018
Context: The fight against malaria is limited by the development of resistance of Plasmodium to medication. This has led to an urgent search for alternative medicinal agents.
Regina A. Kwakye   +3 more
doaj  

IS QUININE AN OXYTOCIC? [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1883
Weaversville, N. C. There has been, and is yet, a controversy among medical men as to whether quinine has oxytocic properties or not, some contending that it has such beyond doubt, and warning the profession to be cautious in its use in cases of pregnancy, and others equally learned and experienced affirming that it is a mistake that quinine has no ...
openaire   +2 more sources

Double Thionation of 4‐Dimethylaminophthalimide Leads to the Development of a Highly Effective Photosensitizer

open access: yesChemistry – A European Journal, EarlyView.
We report on the photophysical properties and electronic relaxation mechanisms of 4‐dimethylaminophthalimide (DMAP) and thio‐4‐dimethylaminophthalimide (SDMAP). While DMAP is fluorescent, SDMAP shows negligible fluorescence due to ultrafast intersystem crossing to a long‐lived triplet state that decays in 3.4 ± 0.05 µs.
Chris Acquah   +8 more
wiley   +1 more source

Flipping the Card With Enantiodivergent Organocatalysis

open access: yesChemistry – A European Journal, EarlyView.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre   +3 more
wiley   +1 more source

Feeder Color and Feeder Position Act As a Cue to Discriminate between Two Diets in Choice Feeding of Chicks

open access: yesThe Journal of Poultry Science, 2005
Chicks were offered a choice between diets added with or without quinine hydro-chloride (HCl) to elucidate the role and efficacy of feeder color (gray or orange) or feeder position (fix or change) in the two-choice preference test.
Hiroshi Ueda   +3 more
doaj   +1 more source

Thermally Activated Delayed Fluorescence: An Extended Study of Peripherally Substituted DMAC‐TRZ Analogues

open access: yesChemistry – A European Journal, EarlyView.
A comprehensive experimental and theoretical study is presented of a family of TADF dyes. Comparing the behavior of structurally related dyes, we uncover the subtle and somewhat unexpected role of conformational degrees of freedom associated with peripheral groups that affect the delicate interplay of excited states that governs spin–orbit coupling ...
Andrea Landi   +7 more
wiley   +1 more source

Quinine-induced bronchiolitis obliterans and organizing pneumonia

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2012
Quinine is a vital anti-malarial drug used in the management of resistant Falciparum malaria. There are previous reports of quinine-induced pulmonary edema and infiltrates.
Masoodur Rahman   +2 more
doaj   +1 more source

Optic Nerve Atrophy in Heroin Intoxication

open access: yesOftalʹmologiâ, 2020
Drug dependence is one of important social problems in modern society. It became more actual because of the high morbidity in young working-age patients. The central nervous system is the main target for psychoactive substances.
E. E. Ioyleva, A. V. Zinov’eva
doaj   +1 more source

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