Results 41 to 50 of about 50,177 (203)
Quinine Inhibits Infection of Human Cell Lines with SARS-CoV-2
Viruses, 2021 While vaccination campaigns are ongoing worldwide, there is still a tremendous medical need for efficient antivirals against SARS-CoV-2 infection. Among several drug candidates, chloroquine (CQN) and hydroxychloroquine (H-CQN) were tested intensively ...
Maximilian Große +12 more
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JAMA: The Journal of the American Medical Association, 1899 A perusal of current literature and an experience with physicians in active practice show many differences of opinion regarding the use and value of quinin in various malarial diseases. The recent war, by exposing large numbers of men to real or imaginary malaria, brought out in a striking manner many of the most common views, and the numerous articles
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Quinine levels in patients with uncomplicated falciparum malaria in the Amazon region of Brazil
Brazilian Journal of Infectious DiseasesWe examined the plasmatic concentrations of quinine in patients with uncomplicated falciparum malaria in an endemic area of the Amazon region in Brazil in a prospective clinical trial, in which a standard three-day course of oral quinine plus doxycycline
José Luiz Fernandes Vieira +3 more
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The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors.
PLoS ONE, 2016 Bitter taste is one of the five basic taste sensations which is mediated by 25 bitter taste receptors (T2Rs) in humans. The mechanism of bitter taste signal transduction is not yet elucidated.
Jasbir D Upadhyaya +5 more
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Des «nanotransporteurs» d’ADN : Repousser les limites des Nanomédicaments pour traiter le cancer
Journal de la Faculté de Médecine d'Oran, 2022 Une nouvelle classe de transporteurs de médicaments fabriqués avec de l’ADN, qui pourrait améliorer de façon importante le traitement des cancers et d’autres maladies, a été conçue et validée par une équipe de chercheur de l’université de Montréal ...
Djawad Chikh
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Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
British Journal of Clinical Pharmacology, EarlyView.Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
Agronomy, 2022 When direct flow velocity measurements are not feasible, the use of tracers can be a valuable tool. In the present study, both laboratory and field experiments were conducted to evaluate the applicability of quinine as a fluorescent tracer for estimating
Soheil Zehsaz +4 more
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British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson +8 more
wiley +1 more source
JAMA: The Journal of the American Medical Association, 1906 Following the cases of pneumonia reported in Dr. Galbraith's article inThe JournalFeb. 10, 1906, I have had many other cases, in all of which I have treated the patients according to Dr. Galbraith's method, but with a very much better result. Pneumonia is a very prevalent disease in Nogales and vicinity.
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