Results 31 to 40 of about 1,804,243 (315)

Gradual acquisition of immunity to severe malaria with increasing exposure. [PDF]

, 2014
Previous analyses have suggested that immunity to non-cerebral severe malaria due to Plasmodium falciparum is acquired after only a few infections, whereas longitudinal studies show that some children experience multiple episodes of severe disease ...
Drakeley, Chris J, Riley, Eleanor M, Griffin, Jamie T., Ghani, Azra C., Reyburn, H., Ghani, Azra C, Griffin, Jamie T, Reyburn, H, Drakeley, Chris J., Drakeley, CJ, Hollingsworth, TD, Reyburn, Hugh, Hollingsworth, T. Déirdre, Hollingsworth, Deirdre, Ghani, AC, Ghani, A. C., Riley, E. M., Griffin, JT, Riley, EM, Drakeley, C. J., Riley, Eleanor, Hollingsworth, T Déirdre, Griffin, J. T.   +22 more
core   +1 more source

Approach to malaria in rural hospitals

CHRISMED Journal of Health and Research, 2014
Malaria is one of the most common parasitic infections in the developing countries. In Rural India, most patients would be treated by primary and secondary care physicians. This article is aimed at providing a feasible approach to the cases of malaria in
Jency Maria Koshy, Jacob Koshy, Vineeth Jaison, Preethi Paul   +3 more
doaj   +1 more source

Comparative analysis of the Immunoglobulin G antibodies (IgG and IgG subclass) responses in children (≤15 years) with severe and uncomplicated malaria in Buea, South West region, Cameroon

Infectious Diseases and Herbal Medicine, 2021
Studies assessing the immunoglobulin G (IgG) antibody responses in severe malaria are not readily available. This study was designed to compare the IgG and IgG1-4 antibody responses in severe malaria and its major clinical presentations (cerebral ...
Tebit Emmanuel Kwenti, Kukwah Anthony Tufon, Babila Raymond Nyasa, Fru Georgia Mbah-Mbole, Faham Khamesipour, Longdoh Anna Njunda   +5 more
doaj   +1 more source

Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria [PDF]

, 2009
Background Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity.
Liles W Conrad, Kain, Kevin C, Kevin C Kain, Kain Kevin C, Liles, W C, Conroy, Andrea L, Conroy Andrea L, Krudsood Srivicha, Erin I Lafferty, Srivicha Krudsood, Lafferty Erin I, Lovegrove, Fiona E, Lafferty, Erin I, Tangpukdee, Noppadon, Fiona E Lovegrove, W Conrad Liles, Tangpukdee Noppadon, Lovegrove Fiona E, Krudsood, Srivicha, Liles, W Conrad, Andrea L Conroy, Noppadon Tangpukdee   +21 more
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Defining childhood severe falciparum malaria for intervention studies. [PDF]

, 2007
Background Clinical trials of interventions designed to prevent severe falciparum malaria in children require a clear endpoint. The internationally accepted definition of severe malaria is sensitive, and appropriate for clinical purposes.
Isaiah Mwangi, Bejon, K, Maitland, Kathryn, Bejon, P, Tabitha Mwangi, J Anthony G Scott, Kevin Marsh, Charles R J C Newton, G. Scott, Berkley, James A, Thomas Williams, Peshu, N, Kathryn Maitland, Brett S Lowe, Berkley, JA, Edna Ogada, Mwangi, I, Norbert Peshu, Brett S. Lowe, Maitland, K, English, M, Lowe, BS, James A Berkley, Newton, Charles RJC, Newton, CR, Peshu, Norbert, Lowe, Brett S, Philip Bejon, Bejon, Philip, Marsh, K, Mwangi, T, Mwangi, Tabitha, Scott, JA, Charles R. J. C. Newton, Williams, T, Scott, J Anthony G, Mike English, Ogada, Edna, J. Anthony, Williams, Thomas, English, Mike, Ogada, E, Mwangi, Isaiah, Marsh, Kevin, James A. Berkley   +44 more
core   +1 more source

Alteration of Blood Lactate Levels in Severe Falciparum Malaria: A Systematic Review and Meta-Analysis

Biology, 2021
Metabolic acidosis in severe malaria usually occurs in the form of lactic acidosis. The present study aimed to collate articles from the literature that have reported blood lactate levels in patients with severe malaria and tested the hypothesis that ...
Polrat Wilairatana, Wanida Mala, Manas Kotepui, Kwuntida Uthaisar Kotepui   +3 more
doaj   +1 more source

Assessment of volume depletion in children with malaria [PDF]

, 2004
Background The degree of volume depletion in severe malaria is currently unknown, although knowledge of fluid compartment volumes can guide therapy. To assist management of severely ill children, and to test the hypothesis that volume changes in fluid ...
Timothy Planche, Kombila Maryvonne, Ward, L, Planche, Timothy, Ward, Leigh, Faucher, JF, Faucher, Jean-François, Les Bluck, Faucher Jean-François, Schwenk, Achim, Antony Wright, Borrmann Steffen, Jean-François Faucher, Krishna Sanjeev, Kombila, Maryvonne, Ward Leigh, Planche, T, Wright, A, Myriam Onanga, Maryvonne Kombila, Bluck, Les, Onanga, Myriam, Achim Schwenk, Borrmann, S, Leigh Ward, Dzeing, A, Peter G Kremsner, Wright Antony, Onanga Myriam, Kombila, M, Kremsner, PG, Kremsner, Peter G., Arnaud Dzeing, Krishna, S, Kremsner Peter G, Dzeing, Arnaud, Wright, Antony, Sanjeev Krishna, Planche Timothy, Krishna, Sanjeev, Bluck Les, Schwenk, A, Borrmann, Steffen, Onanga, M, Steffen Borrmann, Bluck, L, Dzeing Arnaud, Schwenk Achim   +47 more
core   +2 more sources

The prognostic value of measures of acid/base balance in pediatric falciparum malaria, compared with other clinical and laboratory parameters [PDF]

, 2005
Background. Identifying severe, life-threatening falciparum malaria in African children allows for the prompt institution of appropriate management.
Severe Malaria in African Children Network, Taylor, TE, Agbenyega, T, Newton, Charles, Valim, C, Newton, CR, Krishna, S, Wypij, D, Olola, C   +8 more
core   +1 more source

Plasmodium falciparum infection patterns since birth and risk of severe malaria: a nested case-control study in children on the coast of Kenya. [PDF]

PLoS ONE, 2013
Children in malaria endemic areas acquire immunity to severe malaria faster than to mild malaria. Only a minority of children suffers from severe malaria and it is not known what determines this. The aim of this study was to establish how P.
Klara Lundblom, Linda Murungi, Victoria Nyaga, Daniel Olsson, Josea Rono, Faith Osier, Edna Ogada, Scott Montgomery, J Anthony G Scott, Kevin Marsh, Anna Färnert   +10 more
doaj   +1 more source

Overdiagnosis of malaria in patients with severe febrile illness in Tanzania:a prospective study [PDF]

, 2004
Objective: To study the diagnosis and outcomes in people admitted to hospital with a diagnosis of severe malaria in areas with differing intensities of malaria transmission. Design: Prospective observational study of children and adults over the course a
Kitua, Andrew, Greenwood, Brian M, Reyburn, H., Whitty, Christopher J M, Saganda, K., Mwerinde, Ombeni, Kitua, A., Greenwood M., Brian, Mwerinde, O., Drakeley, Chris, Carneiro, I., Mbatia, R., Redepmta Mbatia, Chris Drakeley, Whitty, Christopher JM, Emmanuel Mwakasungula, Whitty J.M, Christopher, Reyburn , Hugh, Raimos Olomi, Mbatia, Redepmta, Saganda, Kapalala, Mwakasungula, E., Ombeni Mwerinde, Olomi, Raimos, Hugh Reyburn, John Shao, Saganda, Kapala, Mwakasungula, Emmanuel, Christopher J M Whitty, Carneiro, Ilona, Kapalala Saganda, Reyburn, Hugh, Greenwood, B.M., Olomi, R., Brian M Greenwood, Drakeley, C., Shao, J., Andrew Kitua, Shao, John, Whitty, C.J., Ilona Carneiro   +40 more
core   +1 more source