Results 61 to 70 of about 235,554 (306)

Molecular Aspects of Severe Malaria [PDF]

open access: yesClinical Microbiology Reviews, 2000
SUMMARYHuman infections with Plasmodium falciparum may result in severe forms of malaria. The widespread and rapid development of drug resistance in P. falciparum and the resistance of the disease-transmitting mosquitoes to insecticides make it urgent to understand the molecular background of the pathogenesis of malaria to enable the development of ...
Q, Chen, M, Schlichtherle, M, Wahlgren
openaire   +2 more sources

Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach. [PDF]

open access: yes, 2015
More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of severe malaria is still not well understood. The majority of malaria cases are caused by Plasmodium falciparum and Plasmodium vivax, which differ in virulence, red ...
Arevalo-Herrera, Myriam   +7 more
core   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang   +17 more
wiley   +1 more source

African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania [PDF]

open access: yes, 2015
X-linked Glucose-6-phosphate dehydrogenase (G6PD) A- deficiency is prevalent in sub-Saharan Africa populations, and has been associated with protection from severe malaria.
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core   +7 more sources

an 8-year multi-centre observational study [PDF]

open access: yes, 2017
Background Malaria remains one of the most serious infections for travellers to tropical countries. Due to the lack of harmonized guidelines a large variety of treatment regimens is used in Europe to treat severe malaria. Methods The European Network for
Antinori, Spinello   +6 more
core   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

open access: yesAnnals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo   +16 more
wiley   +1 more source

Severe imported malaria in a Serbian referral center [PDF]

open access: yesVojnosanitetski Pregled, 2019
Background/Aim. The World Health Organization estimates that 3.2 billion people are at a risk of being infected with malaria. Thus, the adequate diagnostic protocols for malaria, especially those aimed at determining disease severity, are paramount both ...
Poluga Jasmina   +9 more
doaj   +1 more source

Study of complex associations between severe malaria and malnutrition in pediatric age group

open access: yesClinical Epidemiology and Global Health, 2022
Background: In India, severe Malaria as well as malnutrition is quite prevalent in children. Till now, relationship between malnutrition and malaria remains inconclusive.
Deepty Nauriyal, Deepak Kumar
doaj   +1 more source

Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia [PDF]

open access: yes, 2015
This deposit is composed by the main article, and it hasn't any supplementary materials associated.Haemoglobin S (HbS) is the gene known to confer the strongest advantage against malaria morbidity and mortality.
Costa, João   +5 more
core   +2 more sources

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar   +6 more
wiley   +1 more source

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