Results 61 to 70 of about 110,606 (268)

Cytoadherence and virulence - the case of Plasmodium knowlesi malaria. [PDF]

, 2012
BACKGROUND: Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria.
Cox-Singh, J, Craig, Alister G., Lu Woon, Alister G Craig, Farrah A Fatih, Woon, Lu Chan, Siner, Angela, Singh Balbir, Cox-Singh, Janet, Siner Angela, Fatih, FA, Singh, Balbir, Janet Cox-Singh, Singh, B, Balbir Singh, Fatih, Farrah A., Cox-Singh Janet, Krishna Sanjeev, Ahmed, Atique, Siner, A, Angela Siner, Cox Singh, Janet, Ahmed Atique, Craig Alister G, Woon, LC, Woon Lu, Krishna, S, Fatih Farrah A, Sanjeev Krishna, Craig, AG, Krishna, Sanjeev, Ahmed, A, Craig, Alister, Atique Ahmed, Lu Chan Woon   +34 more
core   +1 more source

Liver and kidney dysfunction, hypoglycemia, and thrombocytopenia in Plasmodium vivax malaria patients at a Colombian Northwest region

Parasite Epidemiology and Control, 2021
Plasmodium vivax has high morbidity, it is the Plasmodium species with the greatest worldwide distribution, and its ability to trigger severe symptoms is currently recognized.
Catalina Tovar-Acero, María Camila Velasco, Paula Andrea Avilés-Vergara, Dina Marcela Ricardo-Caldera, Erasmo Manuel Alvis, Javier Ramirez - Montoya, Maria Fernanda Yasnot Acosta   +6 more
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes. [PDF]

, 2009
The prevalence of CD36 deficiency in East Asian and African populations suggests that the causal variants are under selection by severe malaria. Previous analysis of data from the International HapMap Project indicated that a CD36 haplotype bearing a ...
Jallow, Muminatou, Palma, Alejandro, Jeffreys, Anna E, Michael J. Griffiths, Fry, Andrew Evan, Teo, Yik Y, Taylor, Terrie E., Kerrin S. Small, Fry, A. E., Fry, Andrew E., Williams, T. N., Diakite, M, Palma, A., Oduro, Abraham R., Newton, C. R., Kwiatkowski, DP, Anna E. Jeffreys, Pinder, M., Jeffreys, AE, Kwadwo A. Koram, Fry, AE, Kwiatkowski, Dominic, Sisay-Joof, Fatou, Williams, Thomas N., Kirk A. Rockett, Clark, Taane G., Wilson, Jonathan, Rockett, KA, Koram, KA, Abraham R. Oduro, Dominic P. Kwiatkowski, Mahamadou Diakite, Yik Y. Teo, Ghansa, A., Jeffreys, A. E., Kwiatkowski, Dominic P., Campino, S, Anita Ghansa, Taane G. Clark, Koram, Kwadwo, Clark, Taane G, Clark, TG, Malcolm E. Molyneux, Molyneux, Malcolm E, Thomas N. Williams, Ghansa, Anita, Green, Angela, Kevin Marsh, Griffiths, Michael J., Small, Kerrin S, Fatou Sisay-Joof, Pinder, M, Taylor, T. E., Clark, T. G., Susana Campino, Auburn, S., Norbert Peshu, Sarah Auburn, Pardis C. Sabeti, Diakite, Mahamadou, Rockett, Kirk A, Sabeti, PC, Rogers, WO, Oduro, Abraham R, Molyneux, Malcolm E., Jallow, M, Marsh, K, Teo, Yik Y., Small, K. S., Campino, S., Rogers, W. O., Green, A., Koram, Kwadwo A., Marsh, Kevin, Pinder, Margaret, Small, Kerrin S., Angela Green, Oduro, AR, Andrew E. Fry, Teo, YY, Teoh, Yin Yoong Jimmy, Kwiatkowski, D. P., Palma, A, Jonathan Wilson, Peshu, N, Alejandro Palma, Williams, TN, Taylor, Terrie E, Griffiths, M. J., Rockett, K. A., Green, A, William O. Rogers, Terrie E. Taylor, Koram, K. A., Sabeti, Pardis C., Sisay-Joof, F, Newton, Charles R., Teo, Y. Y., Molyneux, ME, Rogers, William O, Oduro, A. R., Peshu, N., Rockett, Kirk A., Jeffreys, Anna E., Auburn, Sarah, Diakite, M., Wilson, J., Auburn, S, Koram, Kwadwo A, Griffiths, MJ, Griffiths, Michael J, Newton, Charles R, Muminatou Jallow, Fry, Andrew E, Small, KS, Newton, CR, Jallow, M., Peshu, Norbert, Campino, Susana, Sabeti, Pardis, Sabeti, P. C., Sisay-Joof, F., Williams, Thomas N, Rogers, William O., Taylor, TE, Wilson, J, Charles R. Newton, Ghansa, A, Margaret Pinder, Williams, Thomas, Sabeti, Pardis C, Kwiatkowski, Dominic P   +131 more
core   +1 more source

Study of complex associations between severe malaria and malnutrition in pediatric age group

Clinical Epidemiology and Global Health, 2022
Background: In India, severe Malaria as well as malnutrition is quite prevalent in children. Till now, relationship between malnutrition and malaria remains inconclusive.
Deepty Nauriyal, Deepak Kumar
doaj   +1 more source

Discovery of an Atypical Arp2/3 Complex in Malaria Parasites Sheds New Light on Nuclear Actin

Cytoskeleton, EarlyView.
ABSTRACT The Arp2/3 complex is a key actin nucleator essential for cytoskeletal dynamics in eukaryotes. Previously believed absent in apicomplexan parasites, we recently identified an atypical Arp2/3 complex in malaria parasites consisting of five divergent subunits and a putative kinetochore‐associated factor.
Franziska Hentzschel, Friedrich Frischknecht, Matthias Marti   +2 more
wiley   +1 more source

Hyponatraemia in imported malaria is common and associated with disease severity

Malaria Journal, 2010
Background Hyponatraemia (serum sodium < 135 mmol/L) has long been recognized as a complication of malaria. However, few studies have been done in non-immune adult populations.
Hoorn Ewout J, Zietse Robert, Hesselink Dennis A, van Wolfswinkel Marlies E, van Genderen Perry JJ   +4 more
doaj   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

The prognostic value of measures of acid/base balance in pediatric falciparum malaria, compared with other clinical and laboratory parameters

, 2005
Background. Identifying severe, life-threatening falciparum malaria in African children allows for the prompt institution of appropriate management.
Severe Malaria in African Children Network, Taylor, TE, Agbenyega, T, Newton, Charles, Valim, C, Newton, CR, Krishna, S, Wypij, D, Olola, C   +8 more
core   +1 more source

Rapid Urban Malaria Appraisal (RUMA) II: epidemiology of urban malaria in Dar es Salaam (Tanzania). [PDF]

, 2006
BACKGROUND\ud \ud The thinking behind malaria research and control strategies stems largely from experience gained in rural areas and needs to be adapted to the urban environment.\ud \ud METHODS\ud \ud A rapid assessment of urban malaria was conducted in
Godson Maro, Wang Shr-Jie, Marcel Tanner, S., Lusinge Manane, Manane, Lusinge, Christian Lengeler, Shr-Jie Wang, Mtasiwa, Deodatus, Deodatus Mtasiwa, Penelope Vounatsou, Marcel Tanner, Lengeler Christian, Vounatsou Penelope, Guéladio Cissé, Maro, G., Wang, S.-J., Lengeler, C., Tanner, Marcel, Lengeler, Christian, Mtasiwa, D., Cissé Guéladio, Mshana, Thomas, Mshana Thomas, Mshana, T., Tanner Marcel, Manane, L., Mtasiwa Deodatus, Maro Godson, Thomas Mshana, Smith Thomas A, Wang, Shr-Jie, Manane Lusinge, Thomas A Smith, Maro, Godson   +33 more
core   +1 more source