Results 81 to 90 of about 1,804,243 (315)

Malaria Policy Advisory Committee to the WHO : conclusions and recommendations of March 2013 meeting [PDF]

, 2013
The Malaria Policy Advisory Committee to the World Health Organization met in Geneva, Switzerland from 13 to 15 March, 2013. This article provides a summary of the discussions, conclusions and recommendations from that meeting.Meeting sessions included ...
WHO Malaria Policy Advisory Committee and Secretariat,, WHO Malaria Policy Advisory Committee and Secretariat   +1 more
core   +1 more source

Characterization of Immune Responses to RBD‐SD1 Nanoparticle Vaccines Derived From ACE2‐Capable HKU5‐CoV‐2, NeoCoV, and HKU5 Merbecoviruses

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles presenting HKU5, NeoCoV, and HKU5‐CoV‐2 RBD‐SD1 induced strong, cross‐reactive IgG responses in immunized mice. The surrogate virus neutralization test demonstrated strong activity in sera from homologous vaccination. ABSTRACT Recent discoveries of merbecoviruses such as HKU5, NeoCoV, and HKU5‐CoV‐2 that use angiotensin ...
Peter J. Halfmann, Jeong Soo Lee, Augustine Duffy, Tong Wang, Bingcheng Huang, James Z. Kurdi, Ajay Inampudi, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +11 more
wiley   +1 more source

Xanthine oxidase levels and immune dysregulation are independently associated with anemia in Plasmodium falciparum malaria

Scientific Reports, 2023
Severe anemia is an important contributor to mortality in children with severe malaria. Anemia in malaria is a multi-factorial complication, since dyserythropoiesis, hemolysis and phagocytic clearance of uninfected red blood cells (RBCs) can contribute ...
Marilyn Vasquez, Margaux Sica, Ruth Namazzi, Robert O. Opoka, Julian Sherman, Dibyadyuti Datta, Miquel Duran-Frigola, John M. Ssenkusu, Chandy C. John, Andrea L. Conroy, Ana Rodriguez   +10 more
doaj   +1 more source

Morbidity from malaria in children in the year after they had received intermittent preventive treatment of malaria: a randomised trial. [PDF]

, 2011
BACKGROUND: Interventions that reduce exposure to malaria infection may lead to delayed malaria morbidity and mortality. We investigated whether intermittent preventive treatment of malaria in children (IPTc) was associated with an increase in the ...
Issa N Ouédraogo, Greenwood, Brian M, Amadou T. Konaté, Tiono, Alfred B, Amidou Z Ouédraogo, Kangoyé, David T, Youssouf Kaboré, Daniel Chandramohan, Ouédraogo, Amidou Z, Soulama, Issiaka, Sirima, Sodiomon B, Issa N. Ouédraogo, Diarra, Amidou, Ouédraogo, Issa N, Amadou T Konaté, Paul J. Milligan, Sodiomon B. Sirima, Yaro, Jean Baptiste, Milligan, Paul J, Gansané, Adama, Alphonse Ouédraogo, Simon Cousens, Alfred B. Tiono, Diallo, Diadier A, Jean Baptiste Yaro, Diadier A. Diallo, Espérance Ouédraogo, Amidou Z. Ouédraogo, Ouédraogo, Alphonse, Adama Gansané, Cousens, Simon, Diadier A Diallo, Alfred B Tiono, Sodiomon B Sirima, David T. Kangoyé, Ouédraogo, Espérance, Chandramohan, Daniel, David T Kangoyé, Paul J Milligan, Issiaka Soulama, Brian M Greenwood, Amidou Diarra, Konaté, Amadou T, Brian M. Greenwood, Kaboré, Youssouf   +44 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Malaria: severe, life threatening. [PDF]

Clinical evidence, 2005
Severe malaria mainly affects children under 5 years old, non-immune travellers, migrants to malarial areas, and people living in areas with unstable or seasonal malaria. Cerebral malaria, causing encephalopathy and coma, is fatal in around 20% of children and adults, and neurological sequelae may occur in some survivors.
Omari, Aika, Garner, Paul
openaire   +4 more sources

Intraleucocytic malaria pigment and prognosis in severe malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1995
The quantity of malaria pigment liberated into the circulation at schizogony reflects the pathogenic sequestered parasite burden in Plasmodium falciparum malaria, and may therefore be a measure of disease severity. Among 300 consecutive adult patients with severe falciparum malaria, the 40 who died had significantly higher proportions of malaria ...
Nguyen, P, Day, N, Pram, T, Ferguson, D, White, N   +4 more
openaire   +2 more sources

Endothelial transcriptomic analysis identifies biomarkers of severe and cerebral malaria

JCI Insight, 2023
Malaria can quickly progress from an uncomplicated infection into a life-threatening severe disease. However, the unspecificity of early symptoms often makes it difficult to identify patients at high risk of developing severe disease.
Cláudia Gomes, Rosauro Varo, Miquel Duran-Frigola, Antonio Sitoe, Rubão Bila, Sonia Machevo, Alfredo Mayor, Quique Bassat, Ana Rodriguez   +8 more
doaj   +1 more source

Case-control approach to identify Plasmodium falciparum polymorphisms associated with severe malaria. [PDF]

, 2009
BACKGROUND: Studies to identify phenotypically-associated polymorphisms in the Plasmodium falciparum 23 Mb genome will require a dense array of marker loci.
David J Conway, Conway, David J, Chokejindachai, Watcharee, Watcharee Chokejindachai   +3 more
core   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source