Results 81 to 90 of about 235,554 (306)

Managing malaria in the intensive care unit. [PDF]

, 2014
The number of people travelling to malaria-endemic countries continues to increase, and malaria remains the commonest cause of serious imported infection in non-endemic areas.
Doherty, JF, Gupta-Wright, A, Marks, M, Singer, M, Walker, D   +4 more
core   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Effectiveness of a Community Intervention on Malaria in Rural Tanzania-A Randomised Controlled Trial. [PDF]

, 2010
Malaria infections are a major public health problem in Africa and prompt treatment is one way of controlling the disease and saving lives. This cluster-randomised controlled community intervention conducted in 2003-2005 aimed at improving early malaria ...
Eriksen, J, Gustafsson, L L, Jahn, A, Kouyaté, B, Mujinja, P, Müller, O, Nsimba, S, Sauerborn, R, Tomson, G, Warsame, M   +9 more
core   +3 more sources

Quantitative electroencephalographic measures during postmalarial epileptogenesis

Epilepsia, EarlyView.
Abstract Objective Severe malaria with neurologic involvement contributes significantly to the global burden of acquired pediatric epilepsy. We studied quantitative electroencephalographic (EEG) measures in postmalarial epileptogenesis. Methods A total of 186 patients, aged 6 months to 11 years, with confirmed central nervous system malaria were ...
Rasesh B. Joshi, Suzanna Mwanza, Hitten P. Zaveri, Joseph Kasolo, Angela Masempela, Thelma Musakanya, Tina Mwale, Violet Nambeye, Rosemary Nyriongo, Ruth A. Tembo, Christopher Cortina, Bo Zhang, Gretchen L. Birbeck, Alexander Rotenberg, Archana A. Patel   +14 more
wiley   +1 more source

The ABO blood group and Plasmodium falciparum malaria in Awash, Metehara and Ziway areas, Ethiopia

Malaria Journal, 2010
Background The virulence of Plasmodium falciparum is associated with the capacity of the infected red blood cell (iRBC) to adhere to uninfected RBCs, a process known as rosetting, which has been linked to the occurrence of severe malaria.
Tekeste Zinaye, Petros Beyene
doaj   +1 more source

Delayed haemolysis after artesunate therapy in a cohort of patients with severe imported malaria due to Plasmodium falciparum [PDF]

, 2016
INTRODUCTION: Delayed haemolytic anaemia is one of the more frequent events after treatment with intravenous artesunate in patients with severe malaria.
Calvo-Cano, Antonia, Gascón i Brustenga, Joaquim, Gómez Junyent, Joan, Muñoz, José, Ruiz-Panales, Pedro   +4 more
core   +1 more source

Incidence and outcomes of childhood status epilepticus in Kano, northern Nigeria

Epilepsia Open, EarlyView.
Abstract Objective Convulsive status epilepticus (CSE) is a major neurological emergency in childhood, but population‐based data from low‐ and middle‐income countries remain limited. We estimated the incidence, mortality, neurological outcomes, and predictors of adverse outcomes among children with CSE in Kano, northern Nigeria.
Umar A. Sabo, Halima Kabir, Aminu T. Abdullahi, Halima Adamu, Auwal S. Salihu, Abba M. Abdullahi, Aminu Wada, Zubairu Iliyasu, Jamilu Zakari, Safiya Gambo, Binta W. Jibir, Muktar H. Aliyu, Usman J. Wudil, Donna J. Ingles, Heather L. Prigmore, Bryan E. Shepherd, Angela R. Paolucci, Edwin Trevathan   +17 more
wiley   +1 more source

An epidemiological analysis of severe imported malaria infections in Sri Lanka, after malaria elimination

Malaria Journal
Background Imported malaria continues to be reported in Sri Lanka after it was eliminated in 2012, and a few progress to life-threatening severe malaria.
Shilanthi Seneviratne, Deepika Fernando, Rajitha Wickremasinghe, Sujai Senarathne, Pubudu Chulasiri, Nethmini Thenuwara, Champa Aluthweera, Iromi Mohotti, Shamila Jayakuru, Thilan Fernando, Anula Wijesundara, Rohini Fernandopulle, Kamini Mendis   +12 more
doaj   +1 more source

Clinical Features and Mortality Associated with Severe Malaria in Adults in Southern Mauritania

Tropical Medicine and Infectious Disease, 2020
Severe malaria in adults is not well-studied in Sahelian Africa. Clinical features and mortality associated with severe Plasmodium falciparum malaria in adult patients hospitalized in Kiffa, southern Mauritania, were analysed.
Boushab Mohamed Boushab, Mohamed Salem Ould Ahmedou Salem, Ali Ould Mohamed Salem Boukhary, Philippe Parola, Leonardo Basco   +4 more
doaj   +1 more source

Intraleucocytic malaria pigment and prognosis in severe malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1995
The quantity of malaria pigment liberated into the circulation at schizogony reflects the pathogenic sequestered parasite burden in Plasmodium falciparum malaria, and may therefore be a measure of disease severity. Among 300 consecutive adult patients with severe falciparum malaria, the 40 who died had significantly higher proportions of malaria ...
Nguyen, P, Day, N, Pram, T, Ferguson, D, White, N   +4 more
openaire   +2 more sources