Results 91 to 100 of about 235,554 (306)

Acidosis in severe childhood malaria [PDF]

QJM, 1997
Data were prospectively collected on 306 Kenyan children, including blood gases in 258 (75%). Severe malaria caused a predominantly high-anion-gap metabolic acidosis in at least 43% of children. Children with coma and respiratory distress (CM + RD) had greater evidence of renal dysfunction, lower mean pH and higher mean plasma osmolality than those ...
English, M., Sauerwein, R.W., Waruiru, C., Mosobo, M., Obiero, J., Lowe, B., Marsh, K.   +6 more
openaire   +5 more sources

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Endothelial transcriptomic analysis identifies biomarkers of severe and cerebral malaria

JCI Insight, 2023
Malaria can quickly progress from an uncomplicated infection into a life-threatening severe disease. However, the unspecificity of early symptoms often makes it difficult to identify patients at high risk of developing severe disease.
Cláudia Gomes, Rosauro Varo, Miquel Duran-Frigola, Antonio Sitoe, Rubão Bila, Sonia Machevo, Alfredo Mayor, Quique Bassat, Ana Rodriguez   +8 more
doaj   +1 more source

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

Food Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi, Naomi A. Mogborukor, Baridoo Donatus Dooka, Polycarp Dauda Madaki, Chiara Frazzoli, Mohamed Haddad, Orish Ebere Orisakwe   +6 more
wiley   +1 more source

Serum Angiopoietin-1 and -2 and VEGF are associated with severe disease in vivax malaria

Journal of Vector Borne Diseases, 2020
Background & objectives: Malaria continues to be a significant public health problem in tropical countries including India; however, there are limited tools to predict occurrence of severe disease due to malaria.
Srinivas H Gowda, Hiren Anghan, Hridesh Mishra, Kunzang Chosdol, Manasvini Bhatt, Vinod Kumar, Piyush Ranjan, Praveen Aggarwal, Naveet Wig, Manish Soneja   +9 more
doaj   +1 more source

Differences in genetic population structures of Plasmodium falciparum isolates from patients along Thai-Myanmar border with severe or uncomplicated malaria [PDF]

, 2008
Background There have been many reports on the population genetic structures of Plasmodium falciparum from different endemic regions, but few studies have examined the characteristics of isolates from patients with different clinical outcomes.
Pannapa Susomboon, Moritoshi Iwagami, Noppadon Tangpukdee, Srivicha Krusood, Sornchai Looareesuwan, Shigeyuki Kano   +5 more
core   +1 more source

Domestic and International Health Expenditure and Health and Healthcare Use: Evidence From Mozambique

Health Economics, EarlyView.
ABSTRACT Evidence on the relationship between public health expenditure and health is mixed and particularly scarce for low‐income countries. Existing studies overlook the subnational distribution of expenditure and rarely distinguish between sources and governance over funding.
Eliana Chavarría‐Pino, Laura Anselmi, Matt Sutton, Sérgio Chicumbe   +3 more
wiley   +1 more source

Presentation of Malaria with Deranged Renal and Biochemical Parameters and its Association with Patient Mortality

Journal of Primary Care Specialties
Introduction: Malaria is a major pediatric health concern, and distinguishing between Malaria and Severe Malaria is crucial for effective management. Objectives: The objective of the study was to analyze key laboratory parameters differentiating Malaria ...
Akanksha D. Srivastava, Vaishali Chauhan, Shivani Bajpai, Jaigam Abbas   +3 more
doaj   +1 more source

Proximate family biosocial variables associated with severe malaria disease among under-five children in resource-poor setting of a rural hospital in eastern Nigeria

Journal of Family Medicine and Primary Care, 2013
Background: Malaria threatens the life of under-five in rural Nigerian families. Although, factors that influence malaria in under-five are manifold. However, family biosocial factors may contribute to the variability of the clinical picture.
Gabriel Uche Pascal Iloh, Abali Chuku, Agwu Nkwa Amadi, John Nnaemeka Ofoedu   +3 more
doaj   +1 more source

Prevalence and spectrum of illness among hospitalized adults with malaria in Blantyre, Malawi [PDF]

, 2014
Background As control interventions are rolled out, the burden of malaria may shift from young children to older children and adults as acquisition of immunity is slowed and persistence of immunity is short-lived.
Allain, Theresa J, Frosch, Anne P, Heyderman, Robert, Laufer, Miriam K, Mathanga, Don P, Molyneux, Malcolm E, SanJoaquin, Miguel, Segula, Dalitso, Skarbinski, Jacek, Taulo, Dalitso   +9 more
core   +3 more sources