Results 101 to 110 of about 1,804,243 (315)
Molecular basis of severe malaria [PDF]
Proceedings of the National Academy of Sciences, 2012 Malaria is an ancient scourge that continues to plague many regions of the developing world. Despite its long history, many aspects of the disease remain difficult to explain. For example, why some individuals experience relatively mild symptoms and others progress to severe and sometimes lethal disease is not understood. Similarly, the molecular basis
Kirk W, Deitsch, Chetan E, Chitnis
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Journal of Primary Care SpecialtiesIntroduction: Malaria is a major pediatric health concern, and distinguishing between Malaria and Severe Malaria is crucial for effective management. Objectives: The objective of the study was to analyze key laboratory parameters differentiating Malaria ...
Akanksha D. Srivastava +3 more
doaj +1 more source
Journal of Family Medicine and Primary Care, 2013 Background: Malaria threatens the life of under-five in rural Nigerian families. Although, factors that influence malaria in under-five are manifold. However, family biosocial factors may contribute to the variability of the clinical picture.
Gabriel Uche Pascal Iloh +3 more
doaj +1 more source
Electron, EarlyView.Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary +5 more
wiley +1 more source
The treatment of complicated and severe malaria [PDF]
British Medical Bulletin, 2005 All cases of falciparum malaria are potentially severe and life threatening, especially when managed inappropriately. A major reason for progression from mild through complicated to severe disease is missed or delayed diagnosis. Once diagnosed, the priority for treatment of complicated and severe disease is the parenteral administration of adequate ...
openaire +2 more sources
Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia [PDF]
, 2006 The Plasmodium falciparum variant erythrocyte surface antigens known as PfEMP1, encoded by the var gene family, are thought to play a crucial role in malaria pathogenesis because they mediate adhesion to host cells and immuno-modulation.
Thera, Mahamadou A +9 more
core +1 more source
Exploration, EarlyView.Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang +9 more
wiley +1 more source
Admission Diagnosis of Cerebral Malaria in Adults in an Endemic Area of Tanzania:Implications and Clinical Description [PDF]
, 2003 Cerebralmalariais commonly diagnosed in adults in endemic areas in Africa, both in hospitals and in the community. This presents a paradox inconsistent with the epidemiological understanding that the development of immunity during childhood confers ...
Liyombo, E +10 more
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Food Safety and Health, EarlyView.This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi +6 more
wiley +1 more source