Results 111 to 120 of about 57,319 (259)

Preoperative Medical Evaluation and Optimisation of Children and Adolescents With Cerebral Palsy (GMFCS IV and V) With Complex Medical Comorbidity Undergoing Lower Limb Orthopaedic Surgery: Results of a Combined Rehabilitation Orthopaedic Paediatric Service

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To describe preoperative medical evaluation, optimisation and acute postoperative outcomes in children and adolescents with cerebral palsy (CP) undergoing lower limb orthopaedic surgery managed in a Combined Rehabilitation Orthopaedic Paediatric Service (CROPS). Methods A retrospective medical record review of children and adolescents with
Jennifer Armstrong   +5 more
wiley   +1 more source

Impact of Hypoxemia Severity on Cardiac Autonomic Regulation in Children With Sleep‐Disordered Breathing: A McGill Oximetry‐Based Analysis

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep‐related breathing disorders (SRBD) represent a significant paediatric health concern. Traditional polysomnographic indices, such as the apnoea–hypopnoea index, may not fully capture the physiological burden of paediatric SRBD, highlighting the need to better characterise the impact of nocturnal hypoxemia on cardiac autonomic regulation ...
Gintare Oboleviciene   +2 more
wiley   +1 more source

Investigating the Link Between Objective Sleep Metrics and Cerebral Small Vessel Disease in a Population‐Based Cohort

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Cerebral small vessel disease (CSVD), a disorder that affects the cerebral microvasculature, is commonly associated with aging and may contribute to dementia and stroke. Increasing evidence suggests a link between CSVD and sleep disturbances, but the association remains poorly understood.
Mareike Ludwig   +11 more
wiley   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila   +1 more
wiley   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

open access: yesExperimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto   +2 more
wiley   +1 more source

Linking dynamic cerebral autoregulation and inhibitory executive function: Role of modifiable behaviours

open access: yesExperimental Physiology, EarlyView.
Abstract Dynamic cerebral autoregulation (dCA) stabilises cerebral blood flow (CBF) against rapid fluctuations in perfusion pressure and may serve as a key physiological mediator of cognitive function. Inhibitory executive function, a core domain essential for goal‐directed behaviour, is influenced by modifiable lifestyle factors such as physical ...
Hayato Tsukamoto, Damian M. Bailey
wiley   +1 more source

Cerebral oxygen extraction across different exercise intensities: Role of arterial PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$

open access: yesExperimental Physiology, EarlyView.
Abstract Stability in cerebral oxygen extraction fraction (OEF) is typically determined by alterations in cerebral blood flow (CBF). At rest, arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$) and OEF exhibit a strong inverse relationship owing to the powerful influence of PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$
L. Madden Brewster   +11 more
wiley   +1 more source

No evidence of higher peak heat tolerance in the afternoon or with opportunity for thermal behaviour during low‐intensity work in uncompensable heat

open access: yesExperimental Physiology, EarlyView.
Abstract Heat tolerance is known to be limited by high brain temperature, but most findings pertain to strenuous exercise following artificially altered baseline temperature or with limited opportunity for behaviour. Therefore, we investigated the hypotheses that thermal perceptions, hyperventilation and cerebrovascular responses would be exacerbated ...
Tiarna Stothers   +5 more
wiley   +1 more source

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