Results 41 to 50 of about 57,319 (259)

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Imaging of an inflammatory injury in the newborn rat brain with photoacoustic tomography. [PDF]

PLoS ONE, 2013
The precise assessment of cerebral saturation changes during an inflammatory injury in the developing brain, such as seen in periventricular leukomalacia, is not well defined.
Edgar Guevara, Romain Berti, Irène Londono, Ningshi Xie, Pierre Bellec, Frédéric Lesage, G A Lodygensky   +6 more
doaj   +1 more source

Arterial oxygen saturation, COPD, and cerebral small vessel disease [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2004
To study whether lower arterial oxygen saturation (SaO(2)) and chronic obstructive pulmonary disease (COPD) are associated with cerebral white matter lesions and lacunar infarcts.We measured SaO(2) twice with a pulse oximeter, assessed the presence of COPD, and performed MRI in 1077 non-demented people from a general population (aged 60-90 years).
van Dijk, E.J., Vermeer, S.E., de Groot, J.C., van de Minkelis, J., Prins, N.D., Oudkerk, M., Hofman, A., Koudstaal, P.J., Breteler, M.M.B.   +8 more
openaire   +2 more sources

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Influencing factors of cerebral oxygen supply-consumption balance and cerebral autoregulation under propofol anesthesia

Di-san junyi daxue xuebao, 2021
Objective To investigate the influencing factors of cerebral oxygen supply-consumption balance and cerebral autoregulation (CA) under propofol anesthesia.
GU Mengyue, CHEN Yan, YANG Chunyong, LU Kaizhi   +3 more
doaj   +1 more source

Preoperative Cerebral Oxygen Saturation and Clinical Outcomes in Cardiac Surgery [PDF]

Anesthesiology, 2011
Background The current study was designed to determine the relation between preoperative cerebral oxygen saturation (Sco2), variables of cardiopulmonary function, mortality, and morbidity in a heterogeneous cohort of cardiac surgery patients. Methods
Matthias, Heringlake, Christof, Garbers, Jan-Hendrik, Käbler, Ingrid, Anderson, Hermann, Heinze, Julika, Schön, Klaus-Ulrich, Berger, Leif, Dibbelt, Hans-Hinrich, Sievers, Thorsten, Hanke   +9 more
openaire   +2 more sources

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Noninvasive optical monitoring of cerebral hemodynamics immediately after birth in neonates with congenital heart disease

Resuscitation Plus
Objective: Critical congenital heart disease is associated with altered cerebral hemodynamics in the neonatal period, but the effect on cerebral physiology earlier in life during the fetal to neonatal transition period is yet to be elucidated.
Chloe N. Winston, Madison E. Bowe, Sura Lee, Nicolina R. Ranieri, Anne Ades, Juliana Gebb, Jack Rychik, Maryam Y. Naim, Anna Bostwick, Rodrigo M. Forti, Tiffany S. Ko, Elizabeth E. Foglia, Wesley B. Baker, Jennifer M. Lynch   +13 more
doaj   +1 more source

Clinical Application of Near-Infrared Spectroscopy in Neonates [PDF]

Neonatal Medicine, 2019
The incidence of cerebral palsy has not decreased despite advances in neonatal care. Preterm infants are at a high risk of cerebral palsy. Moreover, preterm infants might experience permanent neurological sequelae due to injury in the preterm brain ...
Ga Won Jeon
doaj   +1 more source

The Effects of Carotid Endarterectomy Surgery on Cerebral Oxygenation, Randomized Clinical Trial

Ahi Evran Medical Journal, 2022
Purpose: The aim of this study is to assess how NIRS values changed with cross-clamp (CC) duration in carotis endarterectomy (CEA) surgeries. Materials and Methods: The study included 30 patients. Before induction of general anesthesia, systolic blood
Gonca KAYA MERT, Onur AVCI, Oğuz GÜNDOĞDU, Cemil İSBİR, İclal ÖZDEMİR KOL, Sinan GÜRSOY, Kenan KAYGUSUZ   +6 more
doaj   +1 more source