Results 71 to 80 of about 59,892 (241)

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Synchronous surgical treatment for brain and heart in the era of pan ⁃ vascular medicine

Chinese Journal of Contemporary Neurology and Neurosurgery
The concomitant of brain and heart diseases has progressively garnered the attention of neurosurgeons and cardiovascular surgeons, who have initiated synchronous surgical treatment for brain and heart.
SHANG Yan⁃guo, WANG Xuan, TONG Xiao⁃guang, SHI Ming⁃gang, LI Chun⁃hai, WANG Lian⁃qun   +5 more
doaj   +1 more source

The effectiveness of endovascular revascularization of the carotid basin performed before coronary artery bypass grafting in patients with combined atherosclerotic lesions of cerebral and coronary arteries

Ендоваскулярна нейрорентгенохірургія, 2020
Objective – to determine the effectiveness of endovascular revascularization of the carotid pool (carotid stenting) in patients with combined atherosclerotic lesions of the cerebral and coronary arteries, which showed coronary artery bypass grafting ...
S.P. Grigoruk
doaj   +1 more source

Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem Cell Trial of Recovery EnhanceMent After Stroke (STEMS) Pilot Randomized, Controlled Trial (ISRCTN 16784092) [PDF]

, 2006
Background and Purpose - Loss of motor function is common after stroke and leads to significant chronic disability. Stem cells are capable of self-renewal and of differentiating into multiple cell types, including neurones, glia, and vascular cells.
Bath, Philip M.W., Dennis, Martin S., Gray, Laura J., Russell, Nigel, Sprigg, Nikola, Walker, Marion F., Willmot, Mark, Zhao, Lian   +7 more
core   +1 more source

Cerebral in situ ischemic postconditioning: From bench to bedside and beyond

Neuroprotection, EarlyView.
This review explores the translational potential of in situ ischemic postconditioning in acute ischemic stroke. Preclinical and clinical evidence is summarized to highlight its promise as a neuroprotective strategy in the era of endovascular therapy.
Xiao Jiang, Wenbo Zhao, Yongbo Xu, Fanlei Meng, Ming Wei   +4 more
wiley   +1 more source

Screening of postoperative cerebral hyperperfusion syndrome in moyamoya disease: a three-dimensional pulsed arterial-spin labeling magnetic resonance imaging approach

Frontiers in Neuroscience, 2023
IntroductionMoyamoya disease (MMD) is associated with a risk of postoperative cerebral hyperperfusion syndrome (CHS) after revascularization surgery. This study aimed to explore the feasibility of using three-dimensional pulsed arterial spin labeling (3D
Feng Gao, Jianhua Cong, Yu Duan, Wei Zhao, Zhenfang Zhu, Yu Zheng, Liang Jin, Ming Ji, Ming Li   +8 more
doaj   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

Neuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher, Anna F. Dominiczak, Luis M. Garcia‐Segura, Nobuhiro Harada, J. B. Hutchison, James M. Mullin, Delyth Graham, Peter O'Shaughnessy, Hilary Victoria O. Carswell   +8 more
wiley   +1 more source

Pseudo-continuous and territorial arterial spin labeling MRI for assessment of cerebral perfusion in moyamoya disease after revascularization: A comparative study with digital subtraction angiography

Heliyon
Purpose: To evaluate if pseudo-continuous arterial spin labeling (pcASL) and territorial ASL (tASL) can assess cerebral perfusion post-revascularization in Moyamoya disease and compare with digital subtraction angiography (DSA) outcomes.
Juan Li, Qinghu Meng, Ling Huang, Dmytro Pylypenko, Hai Zhong   +4 more
doaj   +1 more source

An examination of factors influencing the choice of therapy for patients with coronary artery disease [PDF]

, 2006
Background A diverse range of factors influence clinicians' decisions regarding the allocation of patients to different treatments for coronary artery disease in routine cardiology clinics. These include demographic measures, risk factors, co-morbidities,
Hirani, S, Hyam, JA, Newman, SP, Shaefi, S, Walesby, RK, Walker, JM   +5 more
core  

Carotid Endarterectomy for Symptomatic Complete Occlusion of the Internal Carotid Artery [PDF]

, 2011
We described 9 consecutive patients who underwent operative carotid artery exploration with attempted carotid endarterectomy (CEA) for symptomatic internal carotid artery (ICA) occlusion.
Chae, Won-Young, Cho, Yong-Pil, Kim, Geun-Eun, Kwon, Sun U., Kwon, Tae-Won   +4 more
core   +1 more source