Results 121 to 130 of about 435,514 (353)

Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3 [PDF]

, 2020
Background: Cerebral small vessel disease is a major cause of dementia and stroke, visible on brain magnetic resonance imaging. Recent data suggest that small vessel disease lesions may be dynamic, damage extends into normal-appearing brain and ...
Arteaga, Carmen, Backhouse, Ellen, Ballerini, Lucia, Bastin, Mark E, Blair, Gordon W, Brown, Rosalind, Chappell, Francesca M, Clancy, Una, Doubal, Fergus N, Garcia, Daniela Jaime, Hamid, Charlene, Hamilton, Iona, Hamilton, Olivia Kl, Hetherington, Kirstie, Hewins, Will, Job, Dominic, Macgillivray, Tom, Maniega, Susana Munoz, Manning, Cameron, Marshall, Ian, Morgan, Alasdair G, Sleight, Emilie, Stringer, Michael S, Thrippleton, Michael J, Valdés-hernández, Maria C, Wardlaw, Joanna M, Wiseman, Stewart   +26 more
core   +2 more sources

Pericyte‐Assisted Vascular Lumen Organization in a Novel Dynamic Human Blood‐Brain Barrier‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino, Elisabetta Perrone, Elisa De Luca, Alberto Rainer, Maura Cesaria, Alessandra Zizzari, Monica Bianco, Giuseppe Gigli, Lorenzo Moroni, Valentina Arima   +9 more
wiley   +1 more source

Chronic kidney disease and its association with cerebral small vessel disease in the general older hypertensive population

BMC Nephrology
Background Cerebral small vessel disease can be identified using magnetic resonance imaging, and includes white matter hyperintensities, lacunar infarcts, cerebral microbleeds, and brain atrophy.
Tomas Månsson, Aldana Rosso, Katarina Ellström, Kasim Abul-Kasim, Sölve Elmståhl   +4 more
doaj   +1 more source

Structural retinal changes in cerebral small vessel disease

Scientific Reports, 2022
Cerebral small vessel disease (CSVD) is an important contributor to cognitive impairment and stroke. Previous research has suggested associations with alterations in single retinal layers. We have assessed changes of all individual retinal layers in CSVD
S. Magdalena Langner, Jan H. Terheyden, Clara F. Geerling, Christine Kindler, Vera C. W. Keil, Christopher A. Turski, Gabrielle N. Turski, Charlotte Behning, Maximilian W. M. Wintergerst, Gabor C. Petzold, Robert P. Finger   +10 more
doaj   +1 more source

Toward Automated Detection of Microbleeds with Anatomical Scale Localization: A Complete Clinical Diagnosis Support Using Deep Learning [PDF]

arXiv, 2023
Cerebral Microbleeds (CMBs) are chronic deposits of small blood products in the brain tissues, which have explicit relation to various cerebrovascular diseases depending on their anatomical location, including cognitive decline, intracerebral hemorrhage, and cerebral infarction.
arxiv  

Effects of Carotid Artery Stiffness on Cerebral Small‐Vessel Disease and Cognition

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
Carotid artery stiffness is associated with cognitive impairment and dementia, however, the underlying mechanism remains unknown. We examined the association of carotid artery stiffness with cerebral small vessel disease (CSVD) markers, cognitive ...
C. Robert, L. Ling, E. Tan, B. Gyanwali, N. Venketasubramanian, S. Lim, Lingli Gong, J. Berboso, A. Richards, Christopher L H Chen, S. Hilal   +10 more
semanticscholar   +1 more source

What is cerebral small vessel disease?

Rinsho Shinkeigaku, 2011
An accumulating amount of evidence suggests that the white matter hyperintensities on T2 weighted brain magnetic resonance imaging predict an increased risk of dementia and gait disturbance. This state has been proposed as cerebral small vessel disease, including leukoaraiosis, Binswanger's disease, lacunar stroke and cerebral microbleeds. However, the
openaire   +4 more sources

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Cortical synapses of the world's smallest mammal: An FIB/SEM study in the Etruscan shrew

Journal of Comparative Neurology, Volume 531, Issue 3, Page 390-414, February 2023., 2023
The present work provides a quantitative dataset of synapses from the Etruscan shrew (the smallest known terrestrial mammal). We have identified common and differing principles of synaptic organization compared to other mammalian species. Abstract The main aim of the present study was to determine if synapses from the exceptionally small brain of the ...
Lidia Alonso‐Nanclares, J. Rodrigo Rodríguez, Angel Merchan‐Perez, Juncal González‐Soriano, Sergio Plaza‐Alonso, Nicolás Cano‐Astorga, Robert K. Naumann, Michael Brecht, Javier DeFelipe   +8 more
wiley   +1 more source

Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study. [PDF]

, 2013
Small vessel disease (mainly hypertensive arteriopathy and cerebral amyloid angiopathy (CAA)) is an important cause of spontaneous intracerebral haemorrhage (ICH), a devastating and still poorly understood stroke type. Enlarged perivascular spaces (EPVS)
Baron, JC, Charidimou, A, Fox, Z, Jäger, HR, Laloux, P, Meegahage, R, Peeters, A, Vandermeeren, Y, Werring, DJ   +8 more
core   +1 more source