Results 111 to 120 of about 265,507 (241)

Plasma inflammatory biomarkers in cerebral small vessel disease: A review

CNS Neuroscience & Therapeutics, 2022
Cerebral small vessel disease (CSVD) is a group of pathological processes affecting small arteries, arterioles, capillaries, and small veins of the brain.
Shuling Wan, Chaitu Dandu, Guangyu Han, Yi-bing Guo, Yuchuan Ding, Haiqing Song, R. Meng   +6 more
semanticscholar   +1 more source

Biomarker advancements in cerebral small vessel disease: An overview

Neural Regeneration Research
Cerebral small vessel disease is a condition caused by chronic cerebral hypoperfusion due to microvascular damage and is a major contributor to stroke and dementia. Traditionally, its diagnosis has relied primarily on neuroimaging findings.
Wenqian Luo, Chenhui Cao, Wenli Li, Ting Wei, Zeyu Zhao, Guanqing Wang, Xiaoli Li, Yanbin Li, Bin Liu   +8 more
doaj   +1 more source

Arterial Stiffness and Cerebral Small Vessel Disease

Frontiers in Neurology, 2018
Background and Objective: Studies on relations between arterial stiffness and full spectrum of radiological features of cerebral small vessel disease (CSVD) are scarce.
Fei-Fei Zhai, Yi-Cong Ye, Si-Yu Chen, Fa-Ming Ding, Fei Han, Xing-Lin Yang, Quan Wang, Li-Xin Zhou, Jun Ni, Ming Yao, Ming-Li Li, Zheng-Yu Jin, Li-Ying Cui, Shu-Yang Zhang, Yi-Cheng Zhu   +14 more
doaj   +1 more source

Imaging scoring methods for cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
The pathogenesis of cerebral small vessel disease (CSVD) is not yet clear, and there is no effective treatment method at present. MRI is an important imaging in diagnosing.
PAN Xi⁃juan, XING Ying⁃qi, LIU Yu⁃mei   +2 more
doaj   +1 more source

Efficacy of antiplatelet therapy in secondary prevention following lacunar stroke:Pooled analysis of randomized trials [PDF]

, 2015
Background and Purpose: Lacunar stroke accounts for ≈25% of ischemic stroke, but optimal antiplatelet regimen to prevent stroke recurrence remains unclear.
Benavente, Oscar R., Copley, Hannah Charlotte, Kwok, Chun Shing, Loke, Yoon K., Myint, Phyo Kyaw, Shoamanesh, Ashkan   +5 more
core   +1 more source

Perivascular space dysfunction in cerebral small vessel disease is related to neuroinflammation

Brain : a journal of neurology
Enlarged perivascular spaces are a feature of cerebral small vessel disease, and it has been hypothesized that they might reflect impaired glymphatic drainage.
Hui Hong, Daniel Tozer, Yutong Chen, Robin B. Brown, Audrey Low, Hugh S Markus   +5 more
semanticscholar   +1 more source

Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease

Nature Medicine, 2021
Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia.
Marie-Gabrielle Duperron, M. Knol, Quentin Le Grand, T. Evans, A. Mishra, A. Tsuchida, Gennady V. Roshchupkin, T. Konuma, D. Trégouët, J. Romero, S. Frenzel, M. Luciano, E. Hofer, M. Bourgey, Nicole D Dueker, P. Delgado, S. Hilal, Rick M. Tankard, Florian Dubost, Jean Shin, Y. Saba, N. Armstrong, Constance Bordes, M. Bastin, A. Beiser, H. Brodaty, R. Bülow, C. Carrera, Christopher P L H Chen, Ching-Yu Cheng, I. Deary, P. Gampawar, Jayanadra J Himali, Jiyang Jiang, T. Kawaguchi, Shuo Li, Mélissa Macalli, P. Marquis, Z. Morris, S. Muñoz Maniega, Susumu Miyamoto, M. Okawa, Matt Paradise, Pedram Parva, T. Rundek, M. Sargurupremraj, Sabrina Schilling, K. Setoh, O. Soukarieh, Y. Tabara, A. Teumer, A. Thalamuthu, J. Trollor, M. V. Valdés Hernández, Meike W. Vernooij, U. Völker, K. Wittfeld, T. Wong, M. Wright, Junyi Zhang, Wanting Zhao, Yi-cheng Zhu, H. Schmidt, P. Sachdev, W. Wen, Kazumichi Yoshida, A. Joutel, C. Satizabal, R. Sacco, G. Bourque, Quentin Le Grand, M. Lathrop, T. Paus, I. Férnandez-Cadenas, Qiong Yang, B. Mazoyer, P. Boutinaud, Y. Okada, H. Grabe, K. Mather, R. Schmidt, M. Joliot, M. Ikram, F. Matsuda, C. Tzourio, J. Wardlaw, S. Seshadri, H. Adams, S. Debette   +88 more
semanticscholar   +1 more source

Asymmetric Dimethylarginine in Cerebral Small Vessel Disease [PDF]

Stroke, 2007
Background and Purpose— Endothelial dysfunction may play a causal role in cerebral small vessel disease (SVD). Asymmetric dimethylarginine (ADMA), a circulating endogenous inhibitor of nitric oxide, has been implicated in endothelial dysfunction, particularly in hyperhomocystinemia, a known risk ...
Usman, Khan, Ahamad, Hassan, Patrick, Vallance, Hugh S, Markus   +3 more
openaire   +2 more sources

Impact of blood pressure variability and cerebral small vessel disease: A systematic review and meta-analysis

Heliyon
Importance: Abnormal blood pressure pattern is an independent risk factor for vascular events. Blood pressure variability can predict cardiovascular and cerebrovascular disease outcomes and is closely associated with the risk of cognitive impairment ...
Bingqing Zhao, Weihua Jia, Ye Yuan, Ying Chen, Yali Gao, Baoling Yang, Wei Zhao, Jingyi Wu   +7 more
doaj   +1 more source

Population Imaging of Cerebral Small Vessel Disease [PDF]

, 2012
As we grow older, our brain tends to shrink. We become increasingly vul nerable to dementia and stroke, two common disorders in the elderly that have great impact on brain functioning and the way people live their lives.
Poels, M.M.F. (Mariëlle)
core   +1 more source