Results 1 to 10 of about 8,915 (192)

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience [PDF]

, 2008
Background: Dementia results from heterogeneous diseases of the brain. Mixed disease forms are increasingly recognized. Methods: We performed a survey within brain banks of BrainNet Europe to estimate the proportion of mixed disease forms underlying ...
Al-Sarraj, Safa, Alafuzoff, Irina, Arzberger, Thomas, Bogdanovic, Nenad, Budka, Herbert, Capellari, Sabina, Ferrer, Isidro, Gelpi, Ellen, Kovacs, Gabor G., Kovari, Viktor, Kretzschmar, Hans, Nagy, Zoltan, Parchi, Piero, Seilhean, Danielle, Soininen, Hilkka, Troakes, Claire   +15 more
core   +1 more source

Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL

Frontiers in Genetics, 2020
Typical cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the human NOTCH3 gene.
Mahmod Panahi, Patricia Rodriguez Rodriguez, Seyed-Mohammad Fereshtehnejad, Seyed-Mohammad Fereshtehnejad, Donia Arafa, Nenad Bogdanovic, Nenad Bogdanovic, Bengt Winblad, Angel Cedazo-Minguez, Juha Rinne, Taher Darreh-Shori, Yoshiki Hase, Raj N. Kalaria, Matti Viitanen, Matti Viitanen, Homira Behbahani   +15 more
doaj   +1 more source

Reduced macular vessel density and inner retinal thickness correlate with the severity of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

PLoS ONE, 2022
BackgroundCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), caused by mutations in NOTCH3, is the most common cause of hereditary cerebral small vessel disease.
Chao-Wen Lin, Zih-Wei Yang, Chih-Hao Chen, Yu-Wen Cheng, Sung-Chun Tang, Jiann-Shing Jeng   +5 more
doaj   +1 more source

CADASIL

Revista Médica del Uruguay, 2008
Introducción: el síndrome CADASIL (Cerebral Dominant Arteriopathy with Subcortical Infarcts and Leukoencephlopathy) es una microangiopatía no amiloidea, no ateromatosa que se transmite en forma autosómica dominante y cuyas principales manifestaciones clínicas ocurren a nivel cerebral.
Alicia Vaglio, Marnels Ferreira, Ana Luisa Panuncio, María Antonia Castagnola, Matías Pebet, Soledad De la Peña, Roberto Quadrelli   +6 more
openaire   +3 more sources

Do Attachment Style and Emotion Regulation Strategies Indicate Distress in Predictive Testing? [PDF]

, 2015
Predictive genetic testing for a neurogenetic disorder evokes strong emotions, and may lead to distress. The aim of this study is to investigate whether attachment style and emotion regulation strategies are associated with distress in persons who ...
Giltay, E.J. (Erik), Meer, L.B. (Lucienne) van der, Tibben, A. (Arend), van Duijn, M.A.J. (Marijtje A. J.)   +3 more
core   +5 more sources

Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases [PDF]

, 2015
Aim: Brain clusterin is known to be associated with the amyloid‐β deposits in Alzheimer's disease (AD). We assessed the distribution of clusterin immunoreactivity in cerebrovascular disorders, particularly focusing on white matter changes in small vessel
Borjesson-Hanson, A, Chen, A, Craggs, L, Deramecourt, V, Hagel, C, Kalaria, RN, Kalimo, H, Kuhlenbaeumer, G, Oakley, AE, Slade, JY, Taylor, J, Viitanen, M   +11 more
core   +1 more source

De novo mutation in the NOTCH3 gene causing CADASIL

Biomolecules & Biomedicine, 2014
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is one of the most common hereditary forms of stroke, and migraine with aura, mood disorders and dementia.
Dragan Stojanov, Danijela Grozdanović, Sladjana Petrović, Daniela Benedeto-Stojanov, Ivan Stefanović, Nebojša Stojanović, Dušica N. Ilić   +6 more
doaj   +1 more source

Generation and characterization of the human iPSC line IDISi001-A isolated from blood cells of a CADASIL patient carrying a NOTCH3 mutation [PDF]

, 2018
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common form of hereditary stroke disorder.
Aramburu-Núñez, Marta, Arias, Susana, Campos, Francisco, Castillo, José, Collado, Manuel, Dell'Era, Patrizia, Fernández-Susavila, Héctor, López-Arias, Esteban, Mora, Cristina, Quintas-Rey, Rita, Sobrino, Tomás   +10 more
core   +3 more sources

Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells

Protein & Cell, 2019
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare hereditary cerebrovascular disease caused by a NOTCH3 mutation.
Chen Ling, Zunpeng Liu, Moshi Song, Weiqi Zhang, Si Wang, Xiaoqian Liu, Shuai Ma, Shuhui Sun, Lina Fu, Qun Chu, Juan Carlos Izpisua Belmonte, Zhaoxia Wang, Jing Qu, Yun Yuan, Guang-Hui Liu   +14 more
doaj   +1 more source

Sex differences in frontotemporal atrophy in CADASIL revealed by 7-Tesla MRI

NeuroImage: Clinical, 2023
Brain damage caused by small vessel disease (SVD) differs between males and females. We aimed to examine the pure sex-specific neuroanatomical mechanisms of SVD adjusted for voxel-based expected effects of age and sex on healthy brain volume.
Xiuqin Jia, Chen Ling, Yingying Li, Jinyuan Zhang, Zhixin Li, Xuejia Jia, Danny J.J. Wang, Zihao Zhang, Yun Yuan, Qi Yang   +9 more
doaj   +1 more source