Results 11 to 20 of about 6,349 (169)

Is migraine a common manifestation of CADASIL? Arguments Pros

The Journal of Headache and Pain
Background Migraine with aura (MA) is a hallmark feature of CADASIL, a hereditary small-vessel disease caused by NOTCH3 mutations. While MA is prevalent in CADASIL, its underlying mechanisms remain unclear, and the links observed can be questioned or ...
Hugues Chabriat
doaj   +2 more sources

Identification of a known mutation in Notch 3 in familiar CADASIL in China. [PDF]

PLoS ONE, 2012
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited disease leading to recurrent ischemic stroke and vascular dementia.
Zhen-Xuan Tan, Fei-Feng Li, You-Yang Qu, Ji Liu, Gui-Rong Liu, Jin Zhou, Yu-Lan Zhu, Shu-Lin Liu   +7 more
doaj   +1 more source

Management of Coronary Artery Disease in CADASIL Patients: Review of Current Literature

Medicina, 2023
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common heritable form of vascular dementia in adults.
Maria Servito, Isha Gill, Joshua Durbin, Nader Ghasemlou, Aron-Frederik Popov, Christopher D. Stephen, Mohammad El-Diasty   +6 more
doaj   +1 more source

Effect of corticosubcortical iron deposition on dysfunction in CADASIL is mediated by white matter microstructural damage

NeuroImage: Clinical, 2023
Iron dysregulation may attenuate cognitive performance in patients with CADASIL. However, the underlying pathophysiological mechanisms remain incompletely understood. Whether white matter microstructural changes mediate these processes is largely unclear.
Xiuqin Jia, Yingying Li, Yunqing Ying, Xuejia Jia, Weijun Tang, Yueyan Bian, Jiajia Zhang, Danny J.J. Wang, Xin Cheng, Qi Yang   +9 more
doaj   +1 more source

The first report of CADASIL in Peru: Olfactory dysfunction on initial presentation

eNeurologicalSci, 2016
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a rare, heritable, small vessel vascular disease caused by mutations in the Notch3 gene that is characterized by migraines, subcortical vascular ...
Anastasia Vishnevetsky, Miguel Inca-Martinez, Karina Milla-Neyra, Danny Moises Barrientos-Iman, Ivan Cornejo-Herrera, Carlos Cosentino, Mario Cornejo-Olivas   +6 more
doaj   +1 more source

Confluent Thalamic Hyperintensities in CADASIL [PDF]

, 2010
Background: CADASIL is responsible for diffuse hyperintensities in the white matter on FLAIR images. These lesions are often associated with focal lesions in the basal ganglia such as lacunar infarctions.
Jacqmin, Mathilde, Viswanathan, Anand, Marco During, Jean-Pierre Guichard, Dichgans, Martin, Martin Dichgans, Herve, Dominique, Düring, Marco, Dominique Hervé, Anand Viswanathan, Guichard, Jean-Pierre, Chabriat, Hugues, Mathilde Jacqmin, Hugues Chabriat   +13 more
core   +1 more source

A Case of CADASIL with NOTCH3 Gene Mutation Presenting with Focal Epileptic Seizure: A Case of CADASIL Presenting with Focal Epileptic Seizure

Archives of Epilepsy, 2023
CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is a hereditary disease of cerebral microvessels with autosomal dominant inheritance due to the NOTCH3 gene mutation. Epileptic seizures were observed in
Gülgün Uncu, Demet İlhan Algın, Oğuz Osman Erdinç, Demet Özbabalık Adapınar   +3 more
doaj   +1 more source

CADASIL: A monogenic condition causing stroke and subcortical vascular dementia [PDF]

, 2002
Mutations in Notch3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an inherited small vessel disease leading to subcortical strokes and vascular dementia. The phenotypic presentation
Dichgans, Martin
core   +1 more source

The pathogenesis of CADASIL: an update

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) appears to be the most common form of hereditary stroke disorder.
Tabira T, CADASIL Grp Vas-Cog, Kalaria RN, Kalimo H, Dichgans M, Viitanen M   +5 more
core   +5 more sources

Клинический случай CADASIL-синдрома у пациентки после новой коронавирусной инфекции COVID-19 [PDF]

, 2023
CADASIL-cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy is the most common form of hereditary cerebral angiopathy and is characterized by recurrent subcortical ischemic strokes, migraine with aura, and cognitive
Е. А. Гаврилова, A. A. Yakovlev, З. Ш. Джалилова, Z. Sh. Dzhalilova, A. G. Smochilin, А. Г. Смочилин, E. A. Gavrilova, А. А. Яковлев   +7 more
core   +4 more sources