Results 21 to 30 of about 6,349 (169)

Is the oxidant/antioxidant status altered in CADASIL patients?

PLoS ONE, 2013
The altered aggregation of proteins in non-native conformation is associated with endoplasmic reticulum derangements, mitochondrial dysfunction and excessive production of reactive oxygen species. Cerebral autosomal dominant arteriopathy with subcortical
Jonica Campolo, Renata De Maria, Caterina Mariotti, Chiara Tomasello, Marina Parolini, Marina Frontali, Domenico Inzitari, Raffaella Valenti, Antonio Federico, Franco Taroni, Oberdan Parodi   +10 more
doaj   +1 more source

Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network

Frontiers in Neurology, 2023
IntroductionData reporting on patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) within the United States population is limited.
Alan P. Pan, Thomas Potter, Abdulaziz Bako, Jonika Tannous, Sudha Seshadri, Louise D. McCullough, Farhaan S. Vahidy, Farhaan S. Vahidy, Farhaan S. Vahidy   +8 more
doaj   +1 more source

CADASIL Syndrome Presenting as Adjustment Disorder

İstanbul Medical Journal, 2020
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), usually referred to as CADASIL, is an inherited autosomal dominant condition that can cause stroke, dementia and other neurological impairments ...
Sevda Bağ, Pelin Özkara, Evrim Erten
doaj   +1 more source

Intracranial Large Artery Abnormalities and Association With Cerebral Small Vessel Disease in CADASIL

Frontiers in Neurology, 2020
Background and objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic arteriopathy, the classic feature of which is small vessel lesions.
Chen Zhang, Wei Li, ShaoWu Li, SongTao Niu, XinGao Wang, Xueying Yu, ZaiQiang Zhang   +6 more
doaj   +1 more source

NIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL [PDF]

, 2012
Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment and predict outcome in acute ischemic stroke.
Herve, Dominique, Jouvent, Eric, Duering, Marco, Chabriat, Hugues, Allili, Nassira, Yao, Ming, Dichgans, Martin   +6 more
core   +1 more source

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL): Three case reports from Serbia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2008
Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary microangiopathy leading to recurrent strokes and vascular dementia in young and middleaged patients.
Zidverc-Trajković Jasna, Lačković Vesna, Pavlović Aleksandra, Bajčetić Miloš, Carević Zvonko, Tomić Gordana, Mandić Gorana, Mijajlović Milija, Jovanović Zagorka, Šternić Nadežda   +9 more
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Lenticulostriate Arteries and Basal Ganglia Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, a High-Field MRI Study

Frontiers in Neurology, 2019
Background and Purpose: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) mainly affects the cerebral small arteries.
Chen Ling, Xiaojing Fang, Xiaojing Fang, Qingle Kong, Qingle Kong, Qingle Kong, Yunchuang Sun, Bo Wang, Bo Wang, Bo Wang, Yan Zhuo, Yan Zhuo, Yan Zhuo, Jing An, Wei Zhang, Zhaoxia Wang, Zihao Zhang, Zihao Zhang, Zihao Zhang, Yun Yuan   +19 more
doaj   +1 more source

Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model

EMBO Molecular Medicine, 2022
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease; no preventive or curative therapy is available. CADASIL is caused by mutations in the
Daniel V Oliveira, Kirsten G Coupland, Wenchao Shao, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, Julie W Rutten, Johan Sandin, Henrik Zetterberg, Johan Lundkvist, Saskia AJ Lesnik Oberstein, Urban Lendahl, Helena Karlström   +13 more
doaj   +1 more source

Reduced macular vessel density and inner retinal thickness correlate with the severity of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

PLoS ONE, 2022
BackgroundCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), caused by mutations in NOTCH3, is the most common cause of hereditary cerebral small vessel disease.
Chao-Wen Lin, Zih-Wei Yang, Chih-Hao Chen, Yu-Wen Cheng, Sung-Chun Tang, Jiann-Shing Jeng   +5 more
doaj   +1 more source

Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL

Frontiers in Genetics, 2020
Typical cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the human NOTCH3 gene.
Mahmod Panahi, Patricia Rodriguez Rodriguez, Seyed-Mohammad Fereshtehnejad, Seyed-Mohammad Fereshtehnejad, Donia Arafa, Nenad Bogdanovic, Nenad Bogdanovic, Bengt Winblad, Angel Cedazo-Minguez, Juha Rinne, Taher Darreh-Shori, Yoshiki Hase, Raj N. Kalaria, Matti Viitanen, Matti Viitanen, Homira Behbahani   +15 more
doaj   +1 more source