Results 31 to 40 of about 3,805 (159)

Intracranial Large Artery Abnormalities and Association With Cerebral Small Vessel Disease in CADASIL

Frontiers in Neurology, 2020
Background and objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic arteriopathy, the classic feature of which is small vessel lesions.
Chen Zhang, Wei Li, ShaoWu Li, SongTao Niu, XinGao Wang, Xueying Yu, ZaiQiang Zhang   +6 more
doaj   +1 more source

On the Diagnosis of CADASIL

Journal of Alzheimer's Disease, 2009
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic arteriopathy related to Notch3 mutations, is difficult to diagnosis. The goal of this study was to determine the value of clinical, immunohistochemical, and molecular techniques for the diagnosis of CADASIL.
Ampuero, I, Alegre-Abarrategui, J, Rodal, I, España, A, Ros, R, Sendón, J, Galloway, E, Cervelló, A, Caminero, AB, Zabala, A, Erro, E, Jarauta, F, Morlán, L, López-Valdés, E, Aladro, Y, Seijo, M, Rivas, G, Muñoz, D, de Yébenes, J   +18 more
openaire   +2 more sources

Cognition in CADASIL [PDF]

Stroke, 2009
CADASIL is an early onset small vessel disease and genetic variant of pure subcortical ischemic vascular dementia (SIVD). The condition has been invaluable in defining the profile and neuroimaging correlates of cognitive deficits in pure SIVD. The recent completion of a randomized trial in cognitively impaired CADASIL patients has illustrated the ...
openaire   +2 more sources

CADASIL Syndrome Presenting as Adjustment Disorder

İstanbul Medical Journal, 2020
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), usually referred to as CADASIL, is an inherited autosomal dominant condition that can cause stroke, dementia and other neurological impairments ...
Sevda Bağ, Pelin Özkara, Evrim Erten
doaj   +1 more source

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL): Three case reports from Serbia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2008
Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary microangiopathy leading to recurrent strokes and vascular dementia in young and middleaged patients.
Zidverc-Trajković Jasna, Lačković Vesna, Pavlović Aleksandra, Bajčetić Miloš, Carević Zvonko, Tomić Gordana, Mandić Gorana, Mijajlović Milija, Jovanović Zagorka, Šternić Nadežda   +9 more
doaj   +1 more source

Lenticulostriate Arteries and Basal Ganglia Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, a High-Field MRI Study

Frontiers in Neurology, 2019
Background and Purpose: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) mainly affects the cerebral small arteries.
Chen Ling, Xiaojing Fang, Xiaojing Fang, Qingle Kong, Qingle Kong, Qingle Kong, Yunchuang Sun, Bo Wang, Bo Wang, Bo Wang, Yan Zhuo, Yan Zhuo, Yan Zhuo, Jing An, Wei Zhang, Zhaoxia Wang, Zihao Zhang, Zihao Zhang, Zihao Zhang, Yun Yuan   +19 more
doaj   +1 more source

Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model

EMBO Molecular Medicine, 2022
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease; no preventive or curative therapy is available. CADASIL is caused by mutations in the
Daniel V Oliveira, Kirsten G Coupland, Wenchao Shao, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, Julie W Rutten, Johan Sandin, Henrik Zetterberg, Johan Lundkvist, Saskia AJ Lesnik Oberstein, Urban Lendahl, Helena Karlström   +13 more
doaj   +1 more source

Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL

Frontiers in Genetics, 2020
Typical cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the human NOTCH3 gene.
Mahmod Panahi, Patricia Rodriguez Rodriguez, Seyed-Mohammad Fereshtehnejad, Seyed-Mohammad Fereshtehnejad, Donia Arafa, Nenad Bogdanovic, Nenad Bogdanovic, Bengt Winblad, Angel Cedazo-Minguez, Juha Rinne, Taher Darreh-Shori, Yoshiki Hase, Raj N. Kalaria, Matti Viitanen, Matti Viitanen, Homira Behbahani   +15 more
doaj   +1 more source

Reduced macular vessel density and inner retinal thickness correlate with the severity of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

PLoS ONE, 2022
BackgroundCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), caused by mutations in NOTCH3, is the most common cause of hereditary cerebral small vessel disease.
Chao-Wen Lin, Zih-Wei Yang, Chih-Hao Chen, Yu-Wen Cheng, Sung-Chun Tang, Jiann-Shing Jeng   +5 more
doaj   +1 more source

De novo mutation in the NOTCH3 gene causing CADASIL

Biomolecules & Biomedicine, 2014
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is one of the most common hereditary forms of stroke, and migraine with aura, mood disorders and dementia.
Dragan Stojanov, Danijela Grozdanović, Sladjana Petrović, Daniela Benedeto-Stojanov, Ivan Stefanović, Nebojša Stojanović, Dušica N. Ilić   +6 more
doaj   +1 more source