Results 1 to 10 of about 10,902,324 (285)

Biomarker advancements in cerebral small vessel disease: An overview

Neural Regeneration Research
Cerebral small vessel disease is a condition caused by chronic cerebral hypoperfusion due to microvascular damage and is a major contributor to stroke and dementia. Traditionally, its diagnosis has relied primarily on neuroimaging findings.
Wenqian Luo, Chenhui Cao, Wenli Li, Ting Wei, Zeyu Zhao, Guanqing Wang, Xiaoli Li, Yanbin Li, Bin Liu   +8 more
doaj   +1 more source

Quantitative comparison of CSVD imaging markers between patients with possible amyloid small vessel disease and with non-amyloid small vessel disease

NeuroImage: Clinical
The spatial distribution patterns of cerebral microbleeds are associated with different types of cerebral small vessel disease (CSVD). This study aims to examine the disparities in brain imaging markers of CSVD among patients diagnosed with possible ...
Chun-Qiang Lu, Ying Liu, Jia-Rong Huang, Meng-Shuang Li, Yan-Shuang Wang, Yan Gu, Di Chang   +6 more
doaj   +1 more source

Chronic kidney disease and its association with cerebral small vessel disease in the general older hypertensive population

BMC Nephrology
Background Cerebral small vessel disease can be identified using magnetic resonance imaging, and includes white matter hyperintensities, lacunar infarcts, cerebral microbleeds, and brain atrophy.
Tomas Månsson, Aldana Rosso, Katarina Ellström, Kasim Abul-Kasim, Sölve Elmståhl   +4 more
doaj   +1 more source

Impact of blood pressure variability and cerebral small vessel disease: A systematic review and meta-analysis

Heliyon
Importance: Abnormal blood pressure pattern is an independent risk factor for vascular events. Blood pressure variability can predict cardiovascular and cerebrovascular disease outcomes and is closely associated with the risk of cognitive impairment ...
Bingqing Zhao, Weihua Jia, Ye Yuan, Ying Chen, Yali Gao, Baoling Yang, Wei Zhao, Jingyi Wu   +7 more
doaj   +1 more source

Cerebral blood flow and cognition after 3 months tadalafil treatment in small vessel disease (ETLAS-2): study protocol for a randomized controlled trial

Trials
Background Targeted treatment is highly warranted for cerebral small vessel disease, a causal factor of one in four strokes and a major contributor to vascular dementia.
Joakim Ölmestig, Kristian Nygaard Mortensen, Birgitte Fagerlund, Nadia Naveed, Mette Maria Nordling, Hanne Christensen, Helle Klingenberg Iversen, Mai Bang Poulsen, Hartwig Roman Siebner, Christina Kruuse   +9 more
doaj   +1 more source

MCC950 suppresses NLRP3-dependent neuroinflammation and ameliorates cognitive decline in a rat model of cerebral small vessel disease

Neural Regeneration Research
Cerebral small vessel disease is a major vascular contributor to cognitive impairment and dementia. However, there remains a lack of effective preventative or therapeutic regimens for cerebral small vessel disease.
Meiyan Zhang, Xiaoyan Lan, Yue Gao, Shen Li, Guanda Qiao, Yajie Liang, Miroslaw Janowski, Piotr Walczak, Chengyan Chu   +8 more
doaj   +1 more source

Quantitative Analysis of Multimodal MRI Markers and Clinical Risk Factors for Cerebral Small Vessel Disease Based on Deep Learning

International Journal of General Medicine
Zhiliang Zhang,1,* Zhongxiang Ding,2,* Fenyang Chen,2 Rui Hua,3 Jiaojiao Wu,3 Zhefan Shen,2 Feng Shi,3 Xiufang Xu1 1School of Medical Imaging, Hangzhou Medical College, Hangzhou, People’s Republic of China; 2Department of Radiology, Affiliated ...
Zhang Z, Ding Z, Chen F, Hua R, Wu J, Shen Z, Shi F, Xu X   +7 more
doaj  

Small vessel disease in the central nervous system

Acta Médica del Centro, 2007
Cerebrovascular disease affects brain arteries by means of occlusion or rupture. Both medium and small sized arteries could be affected. Small vessel occlusion produces lacunar infarcts and small vessel rupture produces intracerebral hemorrhage ...
José Treto Rosal, Ana Hortensia Pérez López   +1 more
doaj  

Cerebral Small Vessel Disease in a Neonate. [PDF]

Ann Neurol
Han Y, Zheng P, Ji X, Chen Q.
europepmc   +1 more source

Roles of Microglia in Cerebral Small Vessel Disease. [PDF]

CNS Neurosci Ther
Jin C, Song X, Sun Y, Peng Y, Zhou J, Wang L, Yin X, Zheng X.   +7 more
europepmc   +1 more source