Results 151 to 160 of about 435,514 (353)

Cerebral Amyloid Angiopathy: An Undeniable Small Vessel Disease [PDF]

Journal of Stroke
Cerebral amyloid angiopathy (CAA) has been proven to be the most common pathological change in cerebral small vessel disease except arteriosclerosis. In recent years, with the discovery of imaging technology and new imaging markers, the diagnostic rate ...
Litao Wang, Qiong Liu, Dongqi Yue, Jun Liu, Yi Fu   +4 more
doaj   +3 more sources

Development of a globally optimised model of the cerebral arteries [PDF]

, 2018
The cerebral arteries are difficult to reproduce from first principles, featuring interwoven territories, and intricate layers of grey and white matter with differing metabolic demand. The aim of this study was to identify the ideal configuration of arteries required to sustain an entire brain hemisphere based on minimisation of the energy required to ...
arxiv   +1 more source

Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris

Advanced Science, EarlyView.
A programmable colloidal microswarm is developed to quickly detach blood clots and enable rapid recanalization, with the detached debris functioning as a magnetic “debris‐robot” that can be efficiently propelled and retrieved via catheter suction, which could significantly save time compared to the critical “Golden 6 hours” window for ischemic stroke ...
Qinglong Wang, Ben Wang, Kai Fung Chan, Xin Song, Qianqian Wang, Fengtong Ji, Lin Su, Bonaventure Yiu Ming Ip, Ho Ko, Philip Wai Yan Chiu, Thomas Wai Hong Leung, Li Zhang   +11 more
wiley   +1 more source

Research progress of cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Cerebral small vessel disease refers to a group of pathological processes with various etiologies that affect small arteries, arterioles, venules, and capillaries of the brain. Recently, the researches of cerebral small vessel disease have got initial
Jun-dong JIA, Wei-dong YUE
doaj  

Cerebral Small Vessel Disease: A Review Focusing on Pathophysiology, Biomarkers, and Machine Learning Strategies

Journal of Stroke, 2018
Cerebral small vessel disease (cSVD) has a crucial role in lacunar stroke and brain hemorrhages and is a leading cause of cognitive decline and functional loss in elderly patients.
E. Cuadrado-Godia, Pratistha Dwivedi, Sanjiv Sharma, A. Ois Santiago, J. Roquer González, M. Balcells, J. Laird, M. Turk, Harman S. Suri, A. Nicolaides, L. Saba, N. Khanna, J. Suri   +12 more
semanticscholar   +1 more source

Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts

Advanced Science, EarlyView.
Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin, Fei He, Haad Rathore, Yingchu Sun, Jia‐ao Zhang, Xinyu Li, Rongkang Yin, Hanlin Zhu, Chong Xie, Lan Luan   +9 more
wiley   +1 more source

Cerebral blood flow and cognition after 3 months tadalafil treatment in small vessel disease (ETLAS-2): study protocol for a randomized controlled trial

Trials
Background Targeted treatment is highly warranted for cerebral small vessel disease, a causal factor of one in four strokes and a major contributor to vascular dementia.
Joakim Ölmestig, Kristian Nygaard Mortensen, Birgitte Fagerlund, Nadia Naveed, Mette Maria Nordling, Hanne Christensen, Helle Klingenberg Iversen, Mai Bang Poulsen, Hartwig Roman Siebner, Christina Kruuse   +9 more
doaj   +1 more source

Towards Transcranial 3D Ultrasound Localization Microscopy of the Nonhuman Primate Brain [PDF]

Hemodynamic changes occur in stroke and neurodegenerative diseases. Developing imaging techniques allowing the in vivo visualization and quantification of cerebral blood flow would help better understand the underlying mechanism of those cerebrovascular diseases.
arxiv   +1 more source

Manipulation of Oxygen Tension in Damaged Regions via Hypoxia‐Induced IPN Hydrogel Microspheres for Intervertebral Disc Regeneration

Advanced Science, EarlyView.
A novel interpenetrating network hydrogel microsphere (NSC‐Exos@HIMS) is developed to manipulate oxygen tension in damaged regions and recruit endogenous stem cells. In vitro and in vivo results show that NSC‐Exos@HIMS maintains the hypoxia microenvironment for up to 5 days, which triggers nucleus pulposus cell‐like differentiation and enhanced ECM ...
Xingdie Zhou, Zhendong Lv, Zehao Chen, Yiming Xu, Chao Lin, Li Liu, Hao Chen, Bing Niu, Wenguo Cui, Yuhui Zhang   +9 more
wiley   +1 more source

Measuring brain beats: Cardiac‐aligned fast functional magnetic resonance imaging signals

Human Brain Mapping, Volume 44, Issue 1, Page 280-294, January 2023., 2023
Blood and cerebrospinal fluid (CSF) pulse and flow throughout the brain, driven by the cardiac cycle. We use rapid functional magnetic resonance imaging (fMRI) measurements to assess blood and CSF flow dynamics in a conventional 3 T magnetic resonance imaging scanner.
Dora Hermes, Hua Wu, Adam B. Kerr, Brian A. Wandell   +3 more
wiley   +1 more source