Results 211 to 220 of about 211,077 (381)

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

Advanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li, Nicolas De Jay, Shan‐Shan Zhang, Xin Fang, Supriya Sharma, Katrina A. Catalano, Venkatesh Sridharan, Zhaoqing Wang, Lei Zhao, Joseph D. Szustakowski, Ching‐Pin Chang, Joseph C. Maranville, Emily R. Holzinger, Erika M. Kvikstad   +13 more
wiley   +1 more source

Oligodendrogenesis in Evolution, Development and Adulthood

Glia, EarlyView.
Oligodendrocytes and myelin took shape in jawed vertebrates. During development, OPCs are originated from NSCs and then undergo differentiation into mature oligodendrocytes that supply myelin. OPCs persist in the adult CNS and continue to produce oligodendrocytes and myelin. Adaptive myelination, which fine‐tunes neural circuits in response to neuronal
Hao Hu, Tianhao Gao, Jingwei Zhao, Huiliang Li   +3 more
wiley   +1 more source

Cognitive function in patients with cerebral small vessel disease : a study on vascular and brain imaging markers [PDF]

, 2014
Marjolein Huijts
openalex   +1 more source

What Does Iron Mean to an Oligodendrocyte?

Glia, EarlyView.
ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley   +1 more source

Carotid artery stenosis is related to cerebral small vessel disease magnetic resonance imaging burden

Heliyon
Background: Cerebral small vessel disease (CSVD) encompasses conditions that affect small blood vessels of the brain, the most common being atherosclerosis.
Stefan Stoisavljevic, Mirjana Zdraljevic, Aleksandra Radojicic, Aleksandra Pavlovic, Milija Mijajlovic   +4 more
doaj  

The concept of sporadic cerebral small vessel disease: A road map on key definitions and current concepts [PDF]

, 2015
Andreas Charidimou, Leonardo Pantoni, Seth Love   +2 more
openalex   +1 more source

Blood-based biomarkers of cerebral small vessel disease

Ageing Research Reviews
Liu-Yun Wu, Yuek Ling Chai, Irwin K. Cheah, Rachel S L Chia, S. Hilal, T. Arumugam, Christopher P Chen, Mitchell Kim Peng Lai   +7 more
semanticscholar   +1 more source

Prognostic Impact of Cerebral Small Vessel Disease on Stroke Outcome [PDF]

, 2015
Beom Joon Kim, Seung‐Hoon Lee
openalex   +1 more source

A dysfunctional blood-brain barrier and cerebral small vessel disease. [PDF]

, 2017
Fisher, MJ, Hainsworth, AH
core   +1 more source

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source