Results 211 to 220 of about 435,514 (353)

CADASIL: A NOTCH3-associated cerebral small vessel disease

Journal of Advanced Research
Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common hereditary cerebral small vessel disease (CSVD), pathologically characterized by a non-atherosclerotic and non-amyloid ...
Lamei Yuan, Xiangyu Chen, Joseph Jankovic, Hao Deng   +3 more
doaj  

A preliminary study on predictors of treatment response to repetitive transcranial magnetic stimulation in patients with treatment‐resistant depression in Japan

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 478-484, December 2022., 2022
Abstract Background Brain imaging studies have reported that the effect of repetitive transcranial magnetic stimulation (rTMS) is associated with the activities of the dorsolateral prefrontal cortex (DLPFC) and ventral medial prefrontal cortex (VMPFC). However, few studies have been conducted in Japanese patients. Aim We aimed to identify brain regions
Haruki Ikawa, Mamoru Tochigi, Yoshihiro Noda, Hiroshi Oba, Tatsuro Kaminaga, Keita Sakurai, Emi Ikebuchi, Naoki Hayashi, Hiroshi Kunugi   +8 more
wiley   +1 more source

Ethnomedicinal uses, phytochemistry, pharmacological activities, and toxicology of the subfamily Gomphrenoideae (Amaranthaceae): A comprehensive review

Chemistry &Biodiversity, Accepted Article.
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves, Giulia Cristina Andreoli de Souza, Alvaro Jose Hernandez Tasco, Marcos Jose Salvador   +3 more
wiley   +1 more source

A head start: The relationship of placental factors to craniofacial and brain development

Developmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver, Martine Dunnwald, Hanna Elizabeth Stevens   +2 more
wiley   +1 more source

Exploring biomarkers of neurodegeneration in epilepsy: Critical insights

Epileptic Disorders, EarlyView.
Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan, Syeda Amrah Hashmi, Jaideep Kapur, Anelyssa D'Abreu, Vineet Punia, Carol Manning, Vanessa L. Smith, Ifrah Zawar   +7 more
wiley   +1 more source

Predicting Stroke through Retinal Graphs and Multimodal Self-supervised Learning [PDF]

arXiv
Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health, leveraging large multimodal datasets for new medical insights.
arxiv  

Features of cognitive dysfunction in late‐onset temporal lobe epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective A global increase in the aging population has resulted in more patients with late‐onset epilepsy. Late‐onset temporal lobe epilepsy (LOTLE) is one of the most common types of late‐onset epilepsy and is frequently accompanied by memory impairments.
Naoya Hasegawa, Natsumi Saito, Masafumi Fukuda   +2 more
wiley   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

Advanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li, Nicolas De Jay, Shan‐Shan Zhang, Xin Fang, Supriya Sharma, Katrina A. Catalano, Venkatesh Sridharan, Zhaoqing Wang, Lei Zhao, Joseph D. Szustakowski, Ching‐Pin Chang, Joseph C. Maranville, Emily R. Holzinger, Erika M. Kvikstad   +13 more
wiley   +1 more source

A development history of cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Cerebral small vessel disease (cSVD) is a group of pathological process with various etiologies that involve small arteries, arterioles, venules and capillaries of the brain, which is closely related to ischemic stroke, cognitive disorders and ...
Ming-rui SONG, Qiao-shu WANG
doaj  

Hippocampal Astrocyte Morphology Follows an Unexpected Trajectory With Age in a Transgenic Rodent Model of Tauopathy

Glia, EarlyView.
ABSTRACT Individual protoplasmic astrocytes have very complex and diverse spongiform shapes. The morphological diversity of astrocytes is determined by the structural and functional interactions of the astrocyte with its microenvironment. When faced with pathological conditions, astrocytes reorganize their morphology.
Emma Augustin, Tatiana Vinasco‐Sandoval, Miriam Riquelme‐Perez, Damien Plassard, Mylène Gaudin, Gwenaëlle Aurégan, Julien Mitja, Sueva Bernier, Charlène Joséphine, Fanny Petit, Caroline Jan, Anne‐Sophie Hérard, Marie‐Claude Gaillard, Agathe Launay, Emilie Faivre, Luc Buée, Anne‐Laurence Boutillier, David Blum, Alexis‐Pierre Bemelmans, Gilles Bonvento, Karine Cambon   +20 more
wiley   +1 more source