Results 191 to 200 of about 127,750 (253)

Evaluating the efficacy of obturator cryoneurolysis for hip adductor spasticity: An observational, prospective study

PM&R, EarlyView.
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae, Mahdis Hashemi, Paul Winston   +2 more
wiley   +1 more source

Association of composite biomarkers with imaging burden in cerebral small vessel disease. [PDF]

Lipids Health Dis
Rao C, Zhu L, Gu T, Zha Z, Yu C.
europepmc   +1 more source

Nomogram integrating MRI radiomics and white matter hyperintensity grading for predicting overall survival in patients with non‐small cell lung cancer and brain metastases receiving whole‐brain radiotherapy

Precision Radiation Oncology, EarlyView.
A prognostic nomogram integrating radiomic features and white matter hyperintensity (WMH) grading was developed to enable individualized survival prediction in patients with brain metastases (BMs). Integration of these imaging biomarkers into the clinical model enhanced predictive performance, indicating their incremental prognostic value for BM ...
Jianan Ni, Yuefeng Lu, Haoli Xu, Xuni Xu, Mengjing Zhao, Yingnan Xue, Gang Li, Yuxia Duan   +7 more
wiley   +1 more source

Baseline Cerebral Small Vessel Disease Predicting Long-Term Cognitive Decline in Transient Ischemic Attack Patients. [PDF]

Eur J Neurol
Roesen P, Temuulen U, Rios AS, Ganeshan R, Braemswig TB, Khalil A, Villringer K, Ihl T, Ali HF, Gebert P, Grittner U, Ahmadi M, Puy L, Cordonnier C, Endres M, Audebert HJ, Kufner A.   +16 more
europepmc   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Statin Therapy Protects White Matter in Cerebral Small Vessel Disease Independent of Lipid-Lowering: Biomarker and Neuroimaging Evidence. [PDF]

Brain Behav
Wang R, Chen J, Ma P, Liu L, Wang Y, Tang Q.   +5 more
europepmc   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Serum cystatin C levels are independently correlated with cognitive impairment in individuals with cerebral small vessel disease. [PDF]

Front Neurosci
Mo D, Li M, Guo X, Zhou L, Yang J, Lei T, Zou W, Lei Q, Wang Q, Li C, Tao X.   +10 more
europepmc   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Composite Markers Predict Functional Outcomes in Basal Ganglia Hemorrhage in Patients with Cerebral Small Vessel Disease. [PDF]

Int J Gen Med
Zha Z, Zhu L, Yu C, Gu T, He C, Zhang X, Wen M.   +6 more
europepmc   +1 more source