Results 1 to 10 of about 4,691,212 (288)

Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]

open access: yesPLoS ONE, 2015
Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos   +3 more
doaj   +2 more sources

Association of Trimethylamine N-Oxide and Its Precursor With Cerebral Small Vessel Imaging Markers

open access: yesFrontiers in Neurology, 2021
Background: High plasma levels of trimethylamine N-oxide (TMAO) and its precursor choline have been linked to stroke; however, their association with cerebral small vessel disease remains unclear.
Yiyi Chen   +140 more
doaj   +1 more source

Posterior white matter hyperintensities are associated with reduced medial temporal lobe subregional integrity and long-term memory in older adults

open access: yesNeuroImage: Clinical, 2023
White matter hyperintensities are a marker of small vessel cerebrovascular disease that are strongly related to cognition in older adults. Similarly, medial temporal lobe atrophy is well-documented in aging and Alzheimer’s disease and is associated with ...
Batool Rizvi   +16 more
doaj   +1 more source

APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia

open access: yesAlzheimer’s Research & Therapy, 2023
Background White matter hyperintensities, a neuroimaging marker of small-vessel cerebrovascular disease and apolipoprotein ε4 (APOE4) allele, are important dementia risk factors.
Ashwati Vipin   +8 more
doaj   +1 more source

Independent and additive contribution of white matter hyperintensities and Alzheimer’s disease pathology to basal forebrain cholinergic system degeneration

open access: yesNeuroImage: Clinical, 2023
Objectives: Degeneration of the cholinergic basal forebrain nuclei (CBFN) system has been studied extensively in Alzheimer's disease (AD). White matter hyperintensities are a hallmark of aging as well as a common co-morbidity of AD, but their ...
Christine Kindler   +5 more
doaj   +1 more source

Association of Low Blood Pressure with White Matter Hyperintensities in Elderly Individuals with Controlled Hypertension [PDF]

open access: yesJournal of Stroke, 2020
Background and Purpose Both hypertension and hypotension increase cerebral white matter hyperintensities. However, the effects of hypotension in individuals with treated hypertension are unknown. We analyzed the association of low blood pressure with the
Jun Sung Kim   +8 more
doaj   +1 more source

Prevalence of white matter hyperintensities is not elevated in a large sample of adolescents and young adults with bipolar disorder [PDF]

open access: yesBrazilian Journal of Psychiatry, 2020
Objective: The increased prevalence rate of white matter hyperintensities is one of the most consistently reported brain abnormalities in adults with bipolar disorder.
Sara Z. Mehrhof   +7 more
doaj   +1 more source

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

open access: yesNeural Regeneration Research, 2021
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly.
Yuexian Cui   +3 more
doaj   +1 more source

Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life

open access: yesScientific Reports, 2021
Epigenetic imprinting is important for neurogenesis and brain function. Hippocampal volumes and brain hyperintensities in late life have been associated with early life circumstances. Epigenetic imprinting may underpin these associations. Methylation was
Marlene Lorgen-Ritchie   +10 more
doaj   +1 more source

Relation between migraine pattern and white matter hyperintensities in brain magnetic resonance imaging

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2018
Background Migraine is a common disorder in general population. Presence of white matter hyperintensities (WMHs) in brain MRI of migraine patients was not studied clearly.
Mohamed Negm   +3 more
doaj   +1 more source

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