Results 41 to 50 of about 4,472,600 (290)

White Matter Hyperintensities and Working Memory: An Explorative Study [PDF]

Aging, Neuropsychology, and Cognition, 2008
White matter hyperintensities (WMH) are commonly observed in elderly people and may have the most profound effect on executive functions, including working memory. Surprisingly, the Digit Span backward, a frequently employed working memory task, reveals no association with WMH. In the present study, it was investigated whether more detailed analyses of
Oosterman, J.M., Harten, B. van, Weinstein, H.C., Scheltens, P., Sergeant, J.A., Scherder, E.J.A.   +5 more
openaire   +3 more sources

Venous Collagenosis as Pathogenesis of White Matter Hyperintensity

Annals of Neurology, 2022
ObjectivePeriventricular white matter hyperintensities (pvWMHs) are commonly observed on MRI in older individuals and are associated with cognitive and motor decline. The etiology of pvWMH remains unknown. Venous collagenosis has been implicated, which may also interfere with perivascular fluid flow leading to dilation of perivascular spaces (PVS ...
David Lahna, Daniel L Schwartz, Randy Woltjer, Sandra E Black, Natalie Roese, Hiroko Dodge, Erin L Boespflug, Julia Keith, Fuqiang Gao, Joel Ramirez, Lisa C Silbert   +10 more
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APOE/TOMM40genetic loci, white matter hyperintensities, and cerebral microbleeds [PDF]

, 2015
Background: Two markers of cerebral small vessel disease are white matter hyperintensities and cerebral microbleeds, which commonly occur in people with Alzheimer's disease.
Lutz, Michael W, Deary, Ian J., Porteous, David J, Harris, Sarah E., Starr, John M., Harris, Sarah, Roses, Allen D., Lyall, Donald M, Royle, Natalie A, Starr, John M, Bastin, Mark E., Royle, Natalie, Munoz-Maniega, Susana; id_orcid, Saunders, Ann M, Valdes Hernandez, Maria, Roses, Allen D, Royle, Natalie A., Bastin, Mark E, Deary, Ian J, Muñoz Maniega, Susana, Lutz, Michael W., Lyall, Donald M., Porteous, David J., Roses, A D, Deary, Ian, Saunders, Ann M., Valdés Hernández, Maria del C., Wardlaw, Joanna M, Murray, Catherine, Valdés Hernández, Maria del C, Lutz, M W, Porteous, David, Wardlaw, Joanna M., Starr, John, Wardlaw, Joanna, Harris, Sarah E, Bastin, Mark   +36 more
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White Matter Hyperintensities: Initial Assessments [PDF]

, 2021
The white matter hyperintensities (WMH, leucoaraiosis) represent the most common kind of ischemic vascular lesion of the white matter due to small vessel diseases, and occurs frequently in the elderly. Consequent to the neuroimaging identification arouse
Moreira, Denise Madeira, Alves, Gilberto Sousa, Engelhardt, Eliasz, Sudo, Felipe Kenji   +3 more
core  

Reference segmentations of white matter hyperintensities from a subset of 20 subjects scanned three consecutive years [PDF]

, 2016
This dataset contains structural magnetic resonance imaging (MRI)-derived data from 20 participants enrolled in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) project.
Valdés Hernández, Maria del C
core   +1 more source

Late-life depression, heart failure and frontal white matter hyperintensity: a structural magnetic resonance imaging study

Brazilian Journal of Medical and Biological Research, 2005
The relevance of the relationship between cardiac disease and depressive symptoms is well established. White matter hyperintensity, a bright signal area in the brain on T2-weighted magnetic resonance imaging scans, has been separately associated with ...
J.R.C. Almeida, T.C.T.F. Alves, M. Wajngarten, J. Rays, C.C. Castro, Q. Cordeiro, R.M.S. Telles, R.J. Fraguas, G.F. Busatto   +8 more
doaj   +1 more source

Morphological Brain Changes after Climbing to Extreme Altitudes--A Prospective Cohort Study. [PDF]

PLoS ONE, 2015
Findings of cerebral cortical atrophy, white matter lesions and microhemorrhages have been reported in high-altitude climbers. The aim of this study was to evaluate structural cerebral changes in a large cohort of climbers after an ascent to extreme ...
Raimund Kottke, Jacqueline Pichler Hefti, Christian Rummel, Martinus Hauf, Urs Hefti, Tobias Michael Merz   +5 more
doaj   +1 more source

White mater hyperintensities and microplastics

ISMRM Annual Meeting
Motivation: White matter hyperintensities are abnormalities that appear in MRI scans of living patients but are not apparent in MRI post-mortem. Goal(s): Our goal is to understand the cellular/biological basis of white matter hyperintensities. Approach: We aligned post-mortem MR scans with those collected antemortem preformed histopathology and pyrGC ...
Elaine L. Bearer, Marcus A. Garcia, Natalie Adolphi, Matthew J. Campen   +3 more
openaire   +2 more sources

Cerebral White Matter Hyperintensity as a Healthcare Quotient [PDF]

Journal of Clinical Medicine, 2019
To better understand the risk factors and optimal therapeutic strategies of cerebral white matter hyperintensity (WMH), we examined a large population of adults with and without various vascular risk factors (VRFs) or vascular risk conditions (VRCs), such as hypertension (HT), diabetes mellitus (DM), and dyslipidemia (DLP), including the comorbidities.
Kaechang Park, Kiyotaka Nemoto, Yoshinori Yamakawa, Fumio Yamashita, Keitaro Yoshida, Masashi Tamura, Atsushi Kawaguchi, Tetsuaki Arai, Makoto Sasaki   +8 more
openaire   +2 more sources

Waxing and waning of white matter hyperintensities

Neurology, 2017
Small vessel disease (SVD) manifests in myriad ways, most prominently as white matter hyperintensities (WMH).1,2 By the age of 60 years, virtually every healthy individual has evidence of WMH,3 and those with ischemic stroke have even more extensive changes.4 Cerebral ischemic injury from occlusion or stenosis of deep penetrating arteries due to ...
de Leeuw, F.E., de Leeuw, F.E., Nichols, F., 3rd   +2 more
openaire   +4 more sources