Results 51 to 60 of about 25,095 (260)

White matter hyperintensities in migraine: a review [PDF]

Precision and Future Medicine, 2019
Migraine is a neurological disorder characterized by recurrent spells of headache accompanied by brain symptoms such as nausea, vomiting, photophobia, and phonophobia.
Mi Ji Lee, Sujin Moon, Chin-Sang Chung
doaj   +1 more source

The Evolution of White Matter Hyperintensities

US Neurology, 2010
White matter hyperintensities (WMHs) are a common finding on magnetic resonance imaging (MRI) scans of elderly subjects. Despite their frequency, the clinical correlates and etiology of WMH remain controversial, with many conflicting results published. This is due, in part, to the varied populations studied. Nevertheless, the prevailing opinion is that
Jillian J Kril, Vanessa G Young
openaire   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

The effects of white matter hyperintensities and amyloid deposition on Alzheimer dementia

NeuroImage: Clinical, 2015
Background and purpose: Elevated levels of amyloid deposition as well as white matter damage are thought to be risk factors for Alzheimer Disease (AD).
Brian A. Gordon, Safa Najmi, Phillip Hsu, Catherine M. Roe, John C. Morris, Tammie L.S. Benzinger   +5 more
doaj   +1 more source

White matter hyperintensity microstructure in amyloid dysmetabolism [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2016
Accumulating evidence suggests associations between cerebrovascular disease (CVD) and Alzheimer’s disease (AD). White matter hyperintensities of presumed vascular origin (WMHs) are increased in subjects with mild cognitive impairment (MCI) and AD, but the exact pathomechanistic link is unknown.
Lisa F, Kalheim, Atle, Bjørnerud, Tormod, Fladby, Kjetil, Vegge, Per, Selnes   +4 more
openaire   +2 more sources

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Divergent functional connectivity changes associated with white matter hyperintensities

NeuroImage
Age-related white matter hyperintensities are a common feature and are known to be negatively associated with structural integrity, functional connectivity, and cognitive performance. However, this has yet to be fully understood mechanistically.
Alexander F. Santillo, Tor O. Strandberg, Nina H. Reislev, Markus Nilsson, Erik Stomrud, Nicola Spotorno, Danielle van Westen, Oskar Hansson   +7 more
doaj   +1 more source

The Characteristics of White Matter Hyperintensities in Patients With Migraine

Frontiers in Pain Research, 2021
Abstract BackgroundThe presence of white matter hyperintensities (WMH) in migraine is well-documented, but the location of brain WMH in patients with migraine are insufficiently researched. Although recent semi-automatic software packages have been developed for calculating WMH, visual inspection remains the gold standard for measuring WMH. The
Catherine Chong, Todd J Schwedt, Meesha Trivedi, Brian W Chong   +3 more
openaire   +3 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Separating Glioma Hyperintensities From White Matter by Diffusion-Weighted Imaging With Spherical Tensor Encoding

Frontiers in Neuroscience, 2022
BackgroundTumor-related hyperintensities in high b-value diffusion-weighted imaging (DWI) are radiologically important in the workup of gliomas. However, the white matter may also appear as hyperintense, which may conflate interpretation.PurposeTo ...
Jan Brabec, Faris Durmo, Filip Szczepankiewicz, Filip Szczepankiewicz, Patrik Brynolfsson, Björn Lampinen, Anna Rydelius, Linda Knutsson, Linda Knutsson, Linda Knutsson, Carl-Fredrik Westin, Pia C. Sundgren, Pia C. Sundgren, Pia C. Sundgren, Markus Nilsson   +14 more
doaj   +1 more source