Results 51 to 60 of about 40,902 (288)

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Pre-operative Cerebral Small Vessel Disease on MR Imaging Is Associated With Cerebral Hyperperfusion After Carotid Endarterectomy

Frontiers in Cardiovascular Medicine, 2021
Objectives: To determine whether pre-operative cerebral small vessel disease is associated with cerebral hyperperfusion (CH) after carotid endarterectomy (CEA).Methods: Seventy-seven patients (mean age of 66 years and 58% male) undergoing CEA for carotid
Xiaoyuan Fan, Zhichao Lai, Tianye Lin, Hui You, Juan Wei, Mingli Li, Changwei Liu, Feng Feng, Feng Feng   +8 more
doaj   +1 more source

Investigating White Matter Lesion Load, Intrinsic Functional Connectivity, and Cognitive Abilities in Older Adults [PDF]

, 2020
Changes to the while matter of the brain disrupt neural communication between spatially distributed brain regions and are associated with cognitive changes in later life.
Kantarovich, Karin
core  

Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging [PDF]

, 2012
Previous neuroimaging research indicates that white matter injury and integrity, measured respectively by white matter hyperintensities (WMH) and fractional anisotropy (FA) obtained from diffusion tensor imaging, differ with aging and cerebrovascular ...
Samuel Neal Lockhart, Samuel Neal Lockhart, Samuel Neal Lockhart, Adriane B. V. Mayda, Adriane B. V. Mayda, Adriane B. V. Mayda, Alexandra E. Roach, Alexandra E. Roach, Alexandra E. Roach, Evan eFletcher, Evan eFletcher, Owen eCarmichael, Owen eCarmichael, Pauline eMaillard, Pauline eMaillard, Christopher G. Schwarz, Christopher G. Schwarz, Andrew P. Yonelinas, Andrew P. Yonelinas, Charan eRanganath, Charan eRanganath, Charles eDeCarli, Charles eDeCarli, Charles eDeCarli, Charles eDeCarli   +24 more
core   +2 more sources

White-matter hyperintensities in first-episode psychosis [PDF]

British Journal of Psychiatry, 2008
BackgroundWhite-matter hyperintensities have been associated with both schizophrenia and mood disorders, particularly bipolar disorder, but results are inconsistent across studiesAimsTo examine whether white-matter hyperintensities are a vulnerability marker for psychosis or are specifically associated with bipolar disorderMethodT2-weighted magnetic ...
Zanetti, Marcus V., Schaufelberger, Maristela S., de Castro, Cláudio C., Menezes, Paulo R., Scazufca, Márcia, McGuire, Philip K., Murray, Robin M., Busatto, Geraldo F.   +7 more
openaire   +2 more sources

Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma, Rhonda Mittenzwei, Heather Maioli, Amanda Kirkland, C. Dirk Keene, Ramon Diaz‐Arrastia, Christine Mac Donald, Chiara Maffei, Brian L. Edlow, Amber L. Nolan   +9 more
wiley   +1 more source

Tract-defined regional white matter hyperintensities and memory

NeuroImage: Clinical, 2020
White matter hyperintensities (WMH) are common radiological findings among older adults and strong predictors of age-related cognitive decline. Recent work has implicated WMH in the pathogenesis and symptom presentation of Alzheimer's disease (AD), which
Batool Rizvi, Patrick J. Lao, Juliet Colón, Christiane Hale, Kay C. Igwe, Atul Narkhede, Mariana Budge, Jennifer J. Manly, Nicole Schupf, Adam M. Brickman   +9 more
doaj   +1 more source

White matter hyperintensities segmentation: a new semi-automated method [PDF]

, 2013
White matter hyperintensities (WMH) are brain areas of increased signal on T2-weighted or fluid-attenuated inverse recovery magnetic resonance imaging (MRI) scans.
Carlo eCaltagirone, Carlo eCaltagirone, Chiara eChiapponi, Claudia eCacciari, Fabrizio ePiras, Giacomo eLuccichenti, Gianfranco eSpalletta, Maria Donata Orfei, Mariangela eIorio   +8 more
core   +2 more sources

White matter hyperintensity microstructure in amyloid dysmetabolism [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2016
Accumulating evidence suggests associations between cerebrovascular disease (CVD) and Alzheimer’s disease (AD). White matter hyperintensities of presumed vascular origin (WMHs) are increased in subjects with mild cognitive impairment (MCI) and AD, but the exact pathomechanistic link is unknown.
Lisa F, Kalheim, Atle, Bjørnerud, Tormod, Fladby, Kjetil, Vegge, Per, Selnes   +4 more
openaire   +2 more sources

Robust White Matter Hyperintensity Segmentation On Unseen Domain

2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI), 2021
Typical machine learning frameworks heavily rely on an underlying assumption that training and test data follow the same distribution. In medical imaging which increasingly begun acquiring datasets from multiple sites or scanners, this identical distribution assumption often fails to hold due to systematic variability induced by site or scanner ...
Zhao, Xingchen, Sicilia, Anthony, Minhas, Davneet, O'Connor, Erin, Aizenstein, Howard, Klunk, William, Tudorascu, Dana, Hwang, Seong Jae   +7 more
openaire   +4 more sources