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Regional vulnerability of brain white matter in vanishing white matter
Vanishing white matter (VWM) is a leukodystrophy that primarily manifests in young children. In this disease, the brain white matter is differentially affected in a predictable pattern with telencephalic brain areas being most severely affected, while ...
Jodie H.K. Man +7 more
doaj +8 more sources
White matter development in early puberty: a longitudinal volumetric and diffusion tensor imaging twin study. [PDF]
White matter microstructure and volume show synchronous developmental patterns in children. White matter volume increases considerably during development.
Rachel M Brouwer +8 more
doaj +2 more sources
Functional magnetic resonance imaging (fMRI) is a non-invasive technique that allows for visualization of activated brain regions. Until recently, fMRI studies have focused on gray matter.
Jodie Reanna Gawryluk +2 more
doaj +3 more sources
The role of white matter myelin in structural-functional network coupling [PDF]
The brain is a complex network of neuronal populations interconnected by white matter tracts. The composition of these white matter connections (SC) shapes inter-regional signaling dynamics giving rise to spatial patterns of synchronous functional ...
Mark C. Nelson +6 more
doaj +2 more sources
White matter hyperintensities and normal-appearing white matter integrity in the aging brain [PDF]
White matter hyperintensities (WMH) of presumed vascular origin are a common finding in brain magnetic resonance imaging of older individuals and contribute to cognitive and functional decline.
Susana Munoz Maniega +2 more
exaly +2 more sources
Fiona S Anderson1, Alicia S Kunin-Batson1, Joanna L Perkins2, K Scott Baker31Divisions of Pediatric Clinical Neuroscience; 2Department of Pediatric Hematology/Oncology, Children’s Hospitals and Clinics, Minneapolis, MN, USA and 3Hematology ...
Fiona S Anderson +3 more
doaj +1 more source
White matter changes underlie hypertension-related cognitive decline in older adults
Hypertension has been well recognized as a risk factor for cognitive impairment and dementia. Although the underlying mechanisms of hypertension-affected cognitive deterioration are not fully understood, white matter changes (WMCs) seem to play an ...
Zilin Li +4 more
doaj +1 more source
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration ...
Nicole I. Wolf +15 more
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Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]
Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos +3 more
doaj +1 more source
Background: The clinical significance of cerebral white matter hyperintensities (WMH) on brain magnetic resonance imaging (MRI) has recently increased, and recognized now as a risk factor for future stroke and dementia. High levels of plasma homocysteine
Kee Ook Lee +6 more
doaj +1 more source

