Spatial coupling of enlarged perivascular spaces and white matter lesions across the Alzheimer's disease continuum [PDF]
Frontiers in NeuroscienceIntroductionEmerging evidence suggests that impaired waste-clearance systems contribute to Alzheimer's disease pathogenesis, yet the etiology of clearance dysfunction markers, such as enlarged perivascular spaces, remains unclear.
Serena Tang +6 more
doaj +2 more sources
Lnc_011797 promotes ferroptosis and aggravates white matter lesions [PDF]
Neural Regeneration ResearchRecent evidence suggests that ferroptosis plays a crucial role in the occurrence and development of white matter lesions. However, the mechanisms and regulatory pathways involved in ferroptosis within white matter lesions remain unclear.
Xiang Xu +7 more
doaj +2 more sources
Role of disturbed structural connectivity network in patients with white matter lesions and cognitive impairment revealed by diffusion-tensor magnetic resonance imaging [PDF]
Journal of International Medical ResearchObjective This study aimed to compare small-world network attributes between control participants without memory complaints and patients with white matter lesions showing cognitive impairment.
Xiaojin Ning +8 more
doaj +2 more sources
Brain Sciences, 2022 This study investigated the characteristics of cognitive impairment in patients with white matter lesions (WMLs) caused by cerebral small vessel disease and the corresponding changes in WM microstructures.
An-Ming Hu +5 more
doaj +3 more sources
Incidence and Risk Factors of White Matter Lesions in Moderate and Late Preterm Infants [PDF]
DiagnosticsBackground: Moderate and late preterm infants (32–36 weeks of gestation) are at significant risk of developmental impairments. Incidence of white matter lesions, which are associated with developmental impairments in very preterm infants, remains ...
Kentaro Ueda +6 more
doaj +2 more sources
Changes in Normal-Appearing White Matter Precede Development of White Matter Lesions [PDF]
Stroke, 2013 Background and Purpose— It is unknown whether white matter lesions (WML) develop abruptly in previously normal brain areas, or whether tissue changes are already present before WML become apparent on MRI. We therefore investigated whether development of WML is preceded by quantifiable changes in normal-appearing white matter ...
Wirô J Niessen, Marius de Groot
exaly +3 more sources
Type I collagen secreted in white matter lesions inhibits remyelination and functional recovery [PDF]
Cell Death and DiseaseWhite matter injury is caused by cerebral blood flow disturbances associated with stroke and demyelinating diseases such as multiple sclerosis. Remyelination is induced spontaneously after white matter injury, but progressive multiple sclerosis and white
Reiji Yamazaki +7 more
doaj +2 more sources
A case of CD36 deficiency with multiple white matter lesions [PDF]
BMC NeurologyBackground CD36 deficiency is associated with abnormal fatty acid metabolism, which may increase the risk of developing atherosclerosis. However, there are few reports on a possible link between CD36 deficiency and cerebral white matter lesions.
Yuta Kizuka +10 more
doaj +2 more sources
White Matter Lesions in Migraine [PDF]
The American Journal of Pathology, 2021 Migraine, the third most common disease worldwide, is a well-known independent risk factor for subclinical focal deep white matter lesions (WMLs), even in young and otherwise healthy individuals with no cardiovascular risk factors. These WMLs are more commonly seen in migraine patients with transient neurologic symptoms preceding their headaches, the ...
Katharina Eikermann-Haerter +1 more
openaire +2 more sources
Neuroprotection and neuroregeneration: roles for the white matter
Neural Regeneration Research, 2022 Efficient strategies for neuroprotection and repair are still an unmet medical need for neurodegenerative diseases and lesions of the central nervous system.
Vito Antonio Baldassarro +4 more
doaj +1 more source