Results 31 to 40 of about 143,855 (296)

Neurovascular-glymphatic dysfunction and white matter lesions [PDF]

GeroScience, 2021
Cerebral white matter lesions (WML) represent a spectrum of age-related structural changes that are identified as areas of white matter high signal intensity on brain magnetic resonance imaging (MRI). Preservation of white matter requires proper functioning of both the cerebrovascular and glymphatic systems.
Behnam Sabayan, Rudi G. J. Westendorp
openaire   +3 more sources

Extent of altered white matter in unilateral and bilateral periventricular white matter lesions in children with unilateral cerebral palsy [PDF]

, 2016
Aims: To investigate the extent of white matter damage in children with unilateral cerebral palsy (UCP) caused by periventricular white matter lesions comparing between unilateral and bilateral lesions; and to investigate a relationship between white ...
Boyd, Roslyn N., Pannek, Kerstin, Rose, S., Fripp, Jurgen, Rose, Stephen E., Pannek, K., Scheck, Simon M., Boyd, Roslyn, Fiori, S., Reid, Lee, Fiori, Simona, Scheck, S., Reid, L., Fripp, J.   +13 more
core   +1 more source

Cerebral white matter lesions and depressive symptons in elderly adults. [PDF]

, 2000
Background: There is evidence for a vascular cause of late-life depression. Cerebral white matter lesions are thought to represent vascular abnormalities.
Jolles, J., Oudkerk, M., Breteler, M.M., de Groot, J.C, Hofman, A., de Leeuw, F E.   +5 more
core   +4 more sources

Alexander Disease Without White Matter Lesions

Pediatric Neurology Briefs, 2006
Seven patients with atypical Alexander disease, showing signs of medulla and spinal cord involvement and little evidence of leukoencephalopathy, are reported from University Medical Center, Amsterdam, the Netherlands; and centers in the UK, USA, Canada ...
J Gordon Millichap
doaj   +1 more source

Depression in small-vessel disease relates to white matter ultrastructural damage, not disability. [PDF]

, 2014
OBJECTIVE: To determine whether cerebral small-vessel disease (SVD) is a specific risk factor for depression, whether any association is mediated via white matter damage, and to study the role of depressive symptoms and disability on quality of life (QoL)
Morris, RG, Brookes, RL, Lawrence, AJ, Morris, Robin G., Lawrence, Andrew J.; id_orcid, Herbert, Vanessa, Herbert, V, Brookes, Rebecca L., Markus, Hugh S., Markus, HS   +9 more
core   +1 more source

Emerging role of white matter lesions in cerebrovascular disease [PDF]

, 2021
White matter lesions have been implicated in the setting of stroke, dementia, intracerebral haemorrhage, several other cerebrovascular conditions, migraine, various neuroimmunological diseases like multiple sclerosis, disorders of metabolism ...
Aarushi Rastogi, Rastogi, Aarushi, Sonu Menachem Maimonides Bhaskar, Robert Weissert, Weissert, Robert, Bhaskar, Sonu Menachem Maimonides   +5 more
core   +1 more source

Tissue transglutaminase in marmoset experimental multiple sclerosis: discrepancy between white and grey matter. [PDF]

PLoS ONE, 2014
Infiltration of leukocytes is a major pathological event in white matter lesion formation in the brain of multiple sclerosis (MS) patients. In grey matter lesions, less infiltration of these cells occur, but microglial activation is present.
Nathaly Espitia Pinzon, Esther Stroo, Bert A 't Hart, John G J M Bol, Benjamin Drukarch, Jan Bauer, Anne-Marie van Dam   +6 more
doaj   +1 more source

Evidence for grey matter MTR abnormality in minimally disabled patients with early relapsing-remitting multiple sclerosis [PDF]

, 2004
Objectives: To establish whether magnetisation transfer ratio (MTR) histograms are sensitive to change in normal appearing grey matter (NAGM) in early relapsing-remitting multiple sclerosis (RRMS) in the absence of significant disability; and to assess ...
Griffin, C M B, Kapoor, R., Miller, D.H., Chard, D T, Hadjiprocopis, A., Ramio-Torrenta, L, Barker, G J; id_orcid, Davies, G.R., Ramió-Torrentà, L., Griffin, C.M.B., Rashid, W., Chard, D.T., Davies, G R, Miller, D H, Rashid, W, Thompson, A.J., Kapoor, R, Thompson, A J, Barker, G.J., Hadjiprocopis, A   +19 more
core   +1 more source

Quantitative MR Imaging and Spectroscopy in Congenital Cytomegalovirus Infection and Periventricular Leukomalacia Suggests a Comparable Neuropathological Substrate of the Cerebral White Matter Lesions [PDF]

, 2009
Congenital cytomegalovirus (CMV) infection and periventricular leukomalacia (PVL) both lead to static cerebral white matter lesions. In contrast to PVL, the neuropathologicAL substrate of these lesions in congenital CMV is not clear. By comparing changes
van der Knaap, M.S., Vermeulen, R.J., Pouwels, P.J.W., Barkhof, F., van der Voorn, J.P.   +4 more
core   +1 more source

Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

Acta Neuropathologica Communications, 2019
Multiple Sclerosis (MS) is the most common cause of acquired neurological disability in young adults, pathologically characterized by leukocyte infiltration of the central nervous system, demyelination of the white and grey matter, and subsequent axonal ...
Thecla A. van Wageningen, Eva Vlaar, Gijs Kooij, Cornelis A. M. Jongenelen, Jeroen J. G. Geurts, Anne-Marie van Dam   +5 more
doaj   +1 more source