Results 11 to 20 of about 143,423 (297)

White matter lesions and intra-arterial thrombolysis [PDF]

open access: yesJournal of Neurology, 2012
The aim of the study was to assess the influence of white matter lesions in patients with acute ischemic stroke treated with intra-arterial thrombolysis (IAT). From September 2003 to January 2010, we treated 400 patients with IAT at our institution. Of these patients, 292 were evaluated with MRI scans and included in this observational study.
Jung S   +13 more
openaire   +4 more sources

Bilateral Striatopallidodentate Calcinosis and Severe White Matter Lesions in Hypoparathyroidism

open access: yesAnnals of Geriatric Medicine and Research, 2016
Basal ganglia calcification occurs frequently in patients with hypoparathyroidism. However, the accompanying changes in the white matter have not been characterized. An 80-year-old woman presented with general weakness. Brain computed tomography revealed
Hye-Yeon Won   +5 more
doaj   +2 more sources

Connecting Cerebral White Matter Lesions and Hypertensive Target Organ Damage [PDF]

open access: yesJournal of Aging Research, 2011
Chronic hypertension leads to concomitant remodeling of the cardiac and vascular systems and various organs, especially the brain, kidney, and retina. The brain is an early target of organ damage due to high blood pressure, which is the major modifiable ...
Cristina Sierra   +2 more
doaj   +2 more sources

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

open access: yesNeural Regeneration Research, 2021
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly.
Yuexian Cui   +3 more
doaj   +1 more source

The Genetics of White Matter Lesions [PDF]

open access: yesCNS Neuroscience & Therapeutics, 2011
White matter lesions (WMLs), commonly seen as hyperintensities on T2‐weighted MRI scans of healthy elderly individuals, are considered to be related to small vessel disease in the brain, and are often associated with subtle cognitive and functional impairments.
Arezoo, Assareh   +4 more
openaire   +2 more sources

Brain White-Matter Lesions and Psychosis [PDF]

open access: yesBritish Journal of Psychiatry, 1989
In a prospective study of late-life onset psychosis, five of the first 27 patients studied had extensive white-matter lesions demonstrated by MRI and/or CT. None of 60 age-matched psychiatrically healthy controls demonstrated such lesions. All five patients had a mild dementia and a frontal behavioural syndrome.
B L, Miller   +7 more
openaire   +4 more sources

White matter lesions in Parkinson disease [PDF]

open access: yesNature Reviews Neurology, 2011
Pure vascular parkinsonism without evidence of nigral Lewy body pathology may occur as a distinct clinicopathological entity, but a much more frequent occurrence is the comorbid presence of age-associated white matter lesions (WMLs) in idiopathic Parkinson disease (PD).
Nicolaas I, Bohnen, Roger L, Albin
openaire   +2 more sources

Altered glutamatergic metabolism associated with punctate white matter lesions in preterm infants. [PDF]

open access: yesPLoS ONE, 2013
Preterm infants (∼10% of all births) are at high-risk for long-term neurodevelopmental disabilities, most often resulting from white matter injury sustained during the neonatal period. Glutamate excitotoxicity is hypothesized to be a key mechanism in the
Jessica L Wisnowski   +8 more
doaj   +1 more source

Clinical Significance of White Matter Lesions in Idiopathic Sudden Sensorineural Hearing Loss

open access: yes, 2022
Background : We aimed to analyze the patient characteristics in accordance with white matter lesions and confirm whether white matter lesions affect final treatment outcomes in idiopathic sudden sensorineural hearing loss. Methods: Medical records of 126
Sung Wan Wan Byun   +11 more
core   +1 more source

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. [PDF]

open access: yes, 2010
Objectives: To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death. Design: Systematic review and meta-analysis.
Debette, S   +6 more
core   +1 more source

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