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Epidemiology of White-Matter Lesions
This is an overview of the prevalence of, and risk factors for white matter lesions in older persons. The prevalence of white matter lesions is high and increases with age. Most risk factors that have been examined in association with white matter lesions are similar to those for cardiovascular disease, including elevated blood pressure, diabetes ...
openaire +3 more sources
Different patterns of white matter degeneration using multiple diffusion indices and volumetric data in mild cognitive impairment and Alzheimer patients [PDF]
Alzheimeŕs disease (AD) represents the most prevalent neurodegenerative disorder that causes cognitive decline in old age. In its early stages, AD is associated with microstructural abnormalities in white matter (WM).
Alves, Gilberto Sousa +31 more
core +2 more sources
Background/aim White matter lesions (WML) are more frequently observed in migraine patients than in the average population. Associations between Helicobacter pylori (H.
Serkan Öcal +2 more
doaj +1 more source
Comparing Cerebral White Matter Lesion Burdens between Parkinson’s Disease with and without Dementia [PDF]
Cerebral white matter lesions (CWMLs) have been suggested to be associated with an increased risk of dementia, disability, and death. CWMLs are more common in individuals with Alzheimer’s disease (AD) than in normal elderly individuals of comparable age.
Sun-Ah Choi +2 more
doaj +1 more source
Magnetic resonance imaging of multiple sclerosis [PDF]
Background: Magnetic resonance imaging (MRI) has an important role in early diagnosis of MS. Multiple sclerosis (MS) is a demyelinating disease of the central nervous system.
Hosny Abd El-Ghany +8 more
doaj +1 more source
Heterogeneity of multiple sclerosis lesions in fast diffusional kurtosis imaging.
BackgroundMean kurtosis (MK), one of the parameters derived from diffusion kurtosis imaging (DKI), has shown increased sensitivity to tissue microstructure damage in several neurological disorders.MethodsThirty-seven patients with relapsing-remitting MS ...
Christian Thaler +12 more
doaj +1 more source
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo +11 more
wiley +1 more source
White Matter Lesions and Cognitive Impairment as Silent Cerebral Disease in Hypertension
Although the pathogenesis and clinical significance of cerebral white matter lesions remain controversial, it is well established that age and hypertension are the most important factors related to the presence of these lesions.
Cristina Sierra, Antonio Coca
doaj +1 more source
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Quantitative histomorphometry of capillary microstructure in deep white matter
White matter lesions represent a major risk factor for dementia in elderly people. Magnetic Resonance Imaging (MRI) studies have demonstrated cerebral blood flow reduction in age-related white matter lesions, indicating that vascular alterations are ...
Meghdoot Mozumder +7 more
doaj +1 more source

