Results 41 to 50 of about 143,423 (297)

Comparing Cerebral White Matter Lesion Burdens between Parkinson’s Disease with and without Dementia [PDF]

Journal of Movement Disorders, 2010
Cerebral white matter lesions (CWMLs) have been suggested to be associated with an increased risk of dementia, disability, and death. CWMLs are more common in individuals with Alzheimer’s disease (AD) than in normal elderly individuals of comparable age.
Sun-Ah Choi, Virgilio Gerald H. Evidente, John N Caviness   +2 more
doaj   +1 more source

Bayesian model selection for pathological neuroimaging data applied to white matter lesion segmentation.

, 2015
In neuroimaging studies, pathologies can present themselves as abnormal intensity patterns. Thus, solutions for detecting abnormal intensities are currently under investigation.
Willem H. Bouvy, Sudre, Carole H., Bouvy, W, Josephine Barnes, Biessels, G, Biessels, Geert Jan, Barnes, Josephine, Sudre, C, Ourselin, Sebastien, Bouvy, Willem H., Sebastien Ourselin, Cardoso, MJ, Ourselin, S, M. Jorge Cardoso, Geert Jan Biessels, Cardoso, M. Jorge, Barnes, J, Sudre, Carole H.; id_orcid, Cardoso, M. Jorge; id_orcid, Carole H. Sudre   +19 more
core   +1 more source

Confluent Thalamic Hyperintensities in CADASIL [PDF]

, 2010
Background: CADASIL is responsible for diffuse hyperintensities in the white matter on FLAIR images. These lesions are often associated with focal lesions in the basal ganglia such as lacunar infarctions.
Jacqmin, Mathilde, Viswanathan, Anand, Marco During, Jean-Pierre Guichard, Dichgans, Martin, Martin Dichgans, Herve, Dominique, Düring, Marco, Dominique Hervé, Anand Viswanathan, Guichard, Jean-Pierre, Chabriat, Hugues, Mathilde Jacqmin, Hugues Chabriat   +13 more
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

The impact of different aetiologies on the cognitive performance of frontal patients.

, 2015
Neuropsychological group study methodology is considered one of the primary methods to further understanding of the organisation of frontal 'executive' functions.
Bozzali, M, Lecce, Francesca, Cipolotti, L, Lecce, F, Healy, C, Shallice, Tim, Bolsover, F, Bozzali, Marco, White, Mark, Healy, Colm, Bolsover, Fay, Spanò, B, CIPOLOTTI, Lisa, Bozzali, M., Shallice, T, Chan, Edgar, Chan, E, White, M, Spanò, Barbara   +18 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Extent of altered white matter in unilateral and bilateral periventricular white matter lesions in children with unilateral cerebral palsy

, 2016
Aims: To investigate the extent of white matter damage in children with unilateral cerebral palsy (UCP) caused by periventricular white matter lesions comparing between unilateral and bilateral lesions; and to investigate a relationship between white ...
Boyd, Roslyn N., Pannek, Kerstin, Rose, S., Fripp, Jurgen, Rose, Stephen E., Pannek, K., Scheck, Simon M., Boyd, Roslyn, Fiori, S., Reid, Lee, Fiori, Simona, Scheck, S., Reid, L., Fripp, J.   +13 more
core   +1 more source

Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study. [PDF]

, 2013
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion volume, brain atrophy, and cerebral microbleeds.
Lawrence, AJ, Barrick, Thomas R., Lawrence Andrew J., Barrick Thomas R., Andrew J Lawrence, Robin G Morris, MacKinnon, Andrew D., Hugh S. Markus, Thomas R Barrick, Bhavini Patel, Robin G. Morris, MacKinnon, AD, Bhavini Patel (405150), Barrick, TR, Philip M. Rich (405153), Markus, HS, Andrew D. MacKinnon, Rich, PM, Thomas R. Barrick (405154), Thomas R. Barrick, Hugh S Markus, Lawrence, Andrew J.; id_orcid, Patel, B, Andrew J. Lawrence, MacKinnon Andrew D., Rich, Philip M., Hugh S. Markus (366687), Andrew J. Lawrence (292444), Robin G. Morris (405151), Morris, RG, Patel Bhavini, Morris Robin G., Morris, Robin G., Andrew D MacKinnon, Rich Philip M., Patel, Bhavini, Philip M Rich, Andrew D. MacKinnon (405152), Markus Hugh S., Philip M. Rich, Markus, Hugh S.   +40 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Quantitative histomorphometry of capillary microstructure in deep white matter

NeuroImage: Clinical, 2019
White matter lesions represent a major risk factor for dementia in elderly people. Magnetic Resonance Imaging (MRI) studies have demonstrated cerebral blood flow reduction in age-related white matter lesions, indicating that vascular alterations are ...
Meghdoot Mozumder, Jose M. Pozo, Santiago Coelho, Marina Costantini, Julie Simpson, J. Robin Highley, Paul G. Ince, Alejandro F. Frangi   +7 more
doaj   +1 more source