Regional distribution of white matter hyperintensities in vascular dementia, Alzheimer's disease and healthy aging [PDF]
Background: White matter hyperintensities (WMH) on MRI scans indicate lesions of the subcortical fiber system. The regional distribution of WMH may be related to their pathophysiology and clinical effect in vascular dementia (VaD), Alzheimer's disease ...
Zebuhr, Y +20 more
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In developing countries, cardiovascular risk factors are poorly controlled, leading to high prevalence of cerebrovascular diseases. The aim of the study was to evaluate the burden of white matter lesions in magnetic resonance through the Fazekas scale in
Elisa de Paula França Resende +9 more
doaj +1 more source
Neurovascular-glymphatic dysfunction and white matter lesions [PDF]
Cerebral white matter lesions (WML) represent a spectrum of age-related structural changes that are identified as areas of white matter high signal intensity on brain magnetic resonance imaging (MRI). Preservation of white matter requires proper functioning of both the cerebrovascular and glymphatic systems.
Behnam Sabayan, Rudi G. J. Westendorp
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Cognitive deficits are associated with frontal and temporal lobe white matter lesions in middle-aged adults living in the community [PDF]
The work was supported by the Leverhulme Trust and the British Academy and was funded by NHMRC of Australia Unit Grant No. 973302, Program Grant No. 179805, NHMRC project grant No.
Helen Christensen +31 more
core +1 more source
Different patterns of punctate white matter lesions in serially scanned preterm infants. [PDF]
With the increased use of MRI in preterm infants, punctate white matter lesions (PWML) are more often recognized. The aim of this study was to describe the incidence and characteristics of these lesions as well as short-term outcome in a cohort of ...
Karina J Kersbergen +6 more
doaj +1 more source
Cerebral White Matter Lesions and the Risk of Dementia [PDF]
To study the association between white matter lesions (WML) in specific locations and the risk of dementia.The Rotterdam Scan Study, a prospective population-based cohort study. We scored periventricular and subcortical WML on magnetic resonance imaging and observed participants until January 2002 for incident dementia.General population.We included ...
Prins, N.D. +7 more
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Bayesian model selection for pathological neuroimaging data applied to white matter lesion segmentation. [PDF]
In neuroimaging studies, pathologies can present themselves as abnormal intensity patterns. Thus, solutions for detecting abnormal intensities are currently under investigation.
Willem H. Bouvy +19 more
core +2 more sources
The Origin of White Matter Lesions [PDF]
See related article, p 1037. Incidental areas of high signal intensity on T2-weighted MRI of older individuals termed white matter hyperintensities or white matter lesions (WML) have sparked scientific and clinical interest over the past 25 years. Extensive research has provided compelling evidence that at least more extensive forms of WMLs are a ...
Franz, Fazekas, Joanna M, Wardlaw
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The impact of different aetiologies on the cognitive performance of frontal patients. [PDF]
Neuropsychological group study methodology is considered one of the primary methods to further understanding of the organisation of frontal 'executive' functions.
Bozzali, M +18 more
core +1 more source
Alexander Disease Without White Matter Lesions
Seven patients with atypical Alexander disease, showing signs of medulla and spinal cord involvement and little evidence of leukoencephalopathy, are reported from University Medical Center, Amsterdam, the Netherlands; and centers in the UK, USA, Canada ...
J Gordon Millichap
doaj +1 more source

