Results 21 to 30 of about 143,423 (297)

Regional distribution of white matter hyperintensities in vascular dementia, Alzheimer's disease and healthy aging [PDF]

, 2004
Background: White matter hyperintensities (WMH) on MRI scans indicate lesions of the subcortical fiber system. The regional distribution of WMH may be related to their pathophysiology and clinical effect in vascular dementia (VaD), Alzheimer's disease ...
Zebuhr, Y, Teipel, S. J., Möller, H. J., Zebuhr, Y., Leinsinger, G., Teipel, SJ, Gootjes, Liselotte, Wismüller, A., Hampel, H, Teipel, S.J, Scheltens, P, Schwarz, R., Scheltens, P., Möller, Hans-Jürgen, Gootjes, L., Wismuller, A, Hampel, H., Moller, HJ, Möller, H.-J., Leinsinger, G, Schwarz, R   +20 more
core   +1 more source

Ischemic cerebrovascular burden evaluated by magnetic resonance imaging in an elderly Brazilian community: The Pietà study

eNeurologicalSci, 2016
In developing countries, cardiovascular risk factors are poorly controlled, leading to high prevalence of cerebrovascular diseases. The aim of the study was to evaluate the burden of white matter lesions in magnetic resonance through the Fazekas scale in
Elisa de Paula França Resende, Luciana Costa-Silva, Karoline Carvalho Carmona, Thais Helena Machado, João Carlos Barbosa Machado, Henrique Cerqueira Guimarães, Maira Tonidandel Barbosa, Antônio Lúcio Teixeira, Leonardo Cruz de Souza, Paulo Caramelli   +9 more
doaj   +1 more source

Cognitive deficits are associated with frontal and temporal lobe white matter lesions in middle-aged adults living in the community [PDF]

, 2010
The work was supported by the Leverhulme Trust and the British Academy and was funded by NHMRC of Australia Unit Grant No. 973302, Program Grant No. 179805, NHMRC project grant No.
Helen Christensen, Kaarin J Anstey, Burns, R, Richard Burns, Perminder S. Sachdev, Cherbuin, N, Anstey, KJ, Christensen, H, David Bunce, Kaarin J. Anstey, Bunce, D, Sachdev, PS ; https://orcid.org/, Wen, W, Wei Wen, Perminder S Sachdev, Christensen, H ; https://orcid.org/, Nicolas Cherbuin, Sachdev, PS   +17 more
core   +1 more source

Different patterns of punctate white matter lesions in serially scanned preterm infants. [PDF]

PLoS ONE, 2014
With the increased use of MRI in preterm infants, punctate white matter lesions (PWML) are more often recognized. The aim of this study was to describe the incidence and characteristics of these lesions as well as short-term outcome in a cohort of ...
Karina J Kersbergen, Manon J N L Benders, Floris Groenendaal, Corine Koopman-Esseboom, Rutger A J Nievelstein, Ingrid C van Haastert, Linda S de Vries   +6 more
doaj   +1 more source

Association between Changes in White Matter Microstructure and Cognitive Impairment in White Matter Lesions

Brain Sciences, 2022
This study investigated the characteristics of cognitive impairment in patients with white matter lesions (WMLs) caused by cerebral small vessel disease and the corresponding changes in WM microstructures.
An-Ming Hu, Yan-Ling Ma, Yue-Xiu Li, Zai-Zhu Han, Nan Yan, Yu-Mei Zhang   +5 more
doaj   +1 more source

Cerebral White Matter Lesions and the Risk of Dementia [PDF]

Archives of Neurology, 2004
To study the association between white matter lesions (WML) in specific locations and the risk of dementia.The Rotterdam Scan Study, a prospective population-based cohort study. We scored periventricular and subcortical WML on magnetic resonance imaging and observed participants until January 2002 for incident dementia.General population.We included ...
Prins, N.D., van Dijk, E.J., den Heijer, T., Vermeer, S.E., Koudstaal, P., Oudkerk, M., Hofman, A., Breteler, M.M.B.   +7 more
openaire   +2 more sources

Neurovascular-glymphatic dysfunction and white matter lesions [PDF]

GeroScience, 2021
Cerebral white matter lesions (WML) represent a spectrum of age-related structural changes that are identified as areas of white matter high signal intensity on brain magnetic resonance imaging (MRI). Preservation of white matter requires proper functioning of both the cerebrovascular and glymphatic systems.
Behnam Sabayan, Rudi G. J. Westendorp
openaire   +3 more sources

The Origin of White Matter Lesions [PDF]

Stroke, 2013
See related article, p 1037. Incidental areas of high signal intensity on T2-weighted MRI of older individuals termed white matter hyperintensities or white matter lesions (WML) have sparked scientific and clinical interest over the past 25 years. Extensive research has provided compelling evidence that at least more extensive forms of WMLs are a ...
Franz, Fazekas, Joanna M, Wardlaw
openaire   +2 more sources

Tissue transglutaminase in marmoset experimental multiple sclerosis: discrepancy between white and grey matter. [PDF]

PLoS ONE, 2014
Infiltration of leukocytes is a major pathological event in white matter lesion formation in the brain of multiple sclerosis (MS) patients. In grey matter lesions, less infiltration of these cells occur, but microglial activation is present.
Nathaly Espitia Pinzon, Esther Stroo, Bert A 't Hart, John G J M Bol, Benjamin Drukarch, Jan Bauer, Anne-Marie van Dam   +6 more
doaj   +1 more source

Cerebral white matter lesions and depressive symptons in elderly adults. [PDF]

, 2000
Background: There is evidence for a vascular cause of late-life depression. Cerebral white matter lesions are thought to represent vascular abnormalities.
Jolles, J., Oudkerk, M., Breteler, M.M., de Groot, J.C, Hofman, A., de Leeuw, F E.   +5 more
core   +3 more sources