Results 21 to 30 of about 5,007,319 (296)

Differential Impact of Plasma Homocysteine Levels on the Periventricular and Subcortical White Matter Hyperintensities on the Brain

Frontiers in Neurology, 2019
Background: The clinical significance of cerebral white matter hyperintensities (WMH) on brain magnetic resonance imaging (MRI) has recently increased, and recognized now as a risk factor for future stroke and dementia. High levels of plasma homocysteine
Kee Ook Lee, Min-Hee Woo, Darda Chung, Jung-Won Choi, Nam-Keun Kim, Ok-Joon Kim, Seung-Hun Oh   +6 more
doaj   +1 more source

Increased functional connectivity of white-matter in myotonic dystrophy type 1

Frontiers in Neuroscience, 2022
BackgroundMyotonic dystrophy type 1 (DM1) is the most common and dominant inherited neuromuscular dystrophy disease in adults, involving multiple organs, including the brain.
Jing Li, Jing Li, Jie Li, Jie Li, Pei Huang, Li-Na Huang, Qing-Guo Ding, Linlin Zhan, Mengting Li, Mengting Li, Jiaxi Zhang, Jiaxi Zhang, Hongqiang Zhang, Lulu Cheng, Lulu Cheng, Huayun Li, Huayun Li, Dong-Qiang Liu, Dong-Qiang Liu, Hai-Yan Zhou, Xi-Ze Jia, Xi-Ze Jia   +21 more
doaj   +1 more source

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. [PDF]

, 2010
Objectives: To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death. Design: Systematic review and meta-analysis.
Debette, S, Markus, H.S., Markus, H S, S. Debette, Debette, Stéphanie, H. S. Markus, Markus, HS   +6 more
core   +1 more source

The spectrum of Ischemia-induced white matter injury varies with age [PDF]

, 2013
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Zammit, Christian, Muscat, Richard, Valentino, Mario   +2 more
core   +1 more source

Cognitive deficits are associated with frontal and temporal lobe white matter lesions in middle-aged adults living in the community [PDF]

, 2010
The work was supported by the Leverhulme Trust and the British Academy and was funded by NHMRC of Australia Unit Grant No. 973302, Program Grant No. 179805, NHMRC project grant No.
Helen Christensen, Kaarin J Anstey, Burns, R, Richard Burns, Perminder S. Sachdev, Cherbuin, N, Anstey, KJ, Christensen, H, David Bunce, Kaarin J. Anstey, Bunce, D, Sachdev, PS ; https://orcid.org/, Wen, W, Wei Wen, Perminder S Sachdev, Christensen, H ; https://orcid.org/, Nicolas Cherbuin, Sachdev, PS, Bunce, David, Christensen Helen, Burns Richard, Wen, Wei, Cherbuin Nicolas, Sachdev, Perminder S., Burns, Richard, Christensen, Helen, Bunce David, Wen Wei, Anstey Kaarin J., Cherbuin, Nicolas, Anstey, Kaarin, Sachdev Perminder S.   +31 more
core   +1 more source

Schizophrenia polygenic risk score influence on white matter microstructure [PDF]

, 2020
Schizophrenia (SZ) and bipolar disorder (BD) are highly heritable, share symptomatology, and have a polygenic architecture. The impact of recent polygenic risk scores (PRS) for psychosis, which combine multiple genome-wide associated risk variations ...
Sukhi Shergill, Elvira Bramon, Colm McDonald, Beatriz Simões, Timothea Toulopoulou, Robin Murray, Hugo Ferreira, Evangelos Vassos, Diana Prata, Fergus Kane, Sridevi Kalidindi   +10 more
core   +1 more source

Depression in small-vessel disease relates to white matter ultrastructural damage, not disability. [PDF]

, 2014
OBJECTIVE: To determine whether cerebral small-vessel disease (SVD) is a specific risk factor for depression, whether any association is mediated via white matter damage, and to study the role of depressive symptoms and disability on quality of life (QoL)
Morris, RG, Brookes, RL, Lawrence, AJ, Morris, Robin G., Lawrence, Andrew J.; id_orcid, Herbert, Vanessa, Herbert, V, Brookes, Rebecca L., Markus, Hugh S., Markus, HS   +9 more
core   +1 more source

Obsessive compulsive symptom dimensions are linked to altered white-matter microstructure in a community sample of youth

Translational Psychiatry, 2022
Obsessive-compulsive symptoms (OCS) are common in school-aged children and predict the development of obsessive compulsive disorder (OCD). White-matter abnormalities have been described in OCD, but the white matter correlates of OCS in the developing ...
Rachael G. Grazioplene, Colin G. DeYoung, Michelle Hampson, Alan Anticevic, Christopher Pittenger   +4 more
doaj   +1 more source

Leukoencephalopathy With Vanishing White Matter: A Review

, 2010
Vanishing white matter (VWM) is one of the most prevalent inherited childhood leukoencephalopathies, but this may affect people ofall ages, including neonates and adults. It is a progressive disorder clinically dominated by cerebellar ataxia and in which
van der Knaap, M.S., Powers, James M., Scheper, G.C., Boor, Ilja, Bugiani, M., Marianna Bugiani, Ilja Boor, van der Knaap, Marjo S., Gert C. Scheper, Boor, I., Marjo S. van der Knaap, Knaap, M.S. van der, Scheper, Gert C., Bugiani, Marianna, Powers, J.M., James M. Powers   +15 more
core   +1 more source

APPLICATION OF STEREOLOGICAL METHODS TO STUDY THE WHITE MATTER AND MYELINATED FIBERS THEREIN OF RAT BRAIN

Image Analysis and Stereology, 2011
An efficient and unbiased stereological method was applied to estimate the white matter volume, the total volume, total length and mean diameter of the myelinated fibers in the white matter and the total volume of the myelin sheaths in the white matter ...
Shu Yang, Chen Li, Wei Zhang, Weiwei Wang, Jens R Nyengaard, Yong Tang   +5 more
doaj   +1 more source