Frontiers in Neurology, 2019 Background: The clinical significance of cerebral white matter hyperintensities (WMH) on brain magnetic resonance imaging (MRI) has recently increased, and recognized now as a risk factor for future stroke and dementia. High levels of plasma homocysteine
Kee Ook Lee +6 more
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Increased functional connectivity of white-matter in myotonic dystrophy type 1
Frontiers in Neuroscience, 2022 BackgroundMyotonic dystrophy type 1 (DM1) is the most common and dominant inherited neuromuscular dystrophy disease in adults, involving multiple organs, including the brain.
Jing Li +21 more
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Divergent longitudinal propagation of white matter degradation in logopenic and semantic variants of primary progressive aphasia [PDF]
, 2015 Background: Clinico-pathological distinction of primary progressive aphasia (PPA) can be challenging at clinic presentation. In particular, cross-sectional neuroimaging signatures across the logopenic (lvPPA) and semantic (svPPA) variants are difficult ...
Agosta +30 more
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Pediatric Neurology Briefs, 1998 Cerebral white matter disorders affecting behavior and cognition are reviewed from the University of Colorado School of Medicine, and Denver VA Medical Center.
J Gordon Millichap
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Probing white-matter microstructure with higher-order diffusion tensors and susceptibility tensor MRI. [PDF]
, 2013 Diffusion MRI has become an invaluable tool for studying white matter microstructure and brain connectivity. The emergence of quantitative susceptibility mapping and susceptibility tensor imaging (STI) has provided another unique tool for assessing the ...
Li, Wei, Liu, Chunlei, Murphy, Nicole E
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Pretreatment cognitive and neural differences between sapropterin dihydrochloride responders and non-responders with phenylketonuria [PDF]
, 2017 Sapropterin dihydrochloride (BH4) reduces phenylalanine (Phe) levels and improves white matter integrity in a subset of individuals with phenylketonuria (PKU) known as “responders.” Although prior research has identified biochemical and genotypic ...
Christ, Shawn E +5 more
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Interleukin-6, age, and corpus callosum integrity. [PDF]
, 2014 The contribution of inflammation to deleterious aging outcomes is increasingly recognized; however, little is known about the complex relationship between interleukin-6 (IL-6) and brain structure, or how this association might change with increasing age.
Bettcher, Brianne M +13 more
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Rethinking the standard trans-cortical approaches in the light of superficial white matter anatomy
Neural Regeneration Research, 2015 A better comprehension of the superficial white matter organization is important in order to minimize potential and avoidable damage to long or intermediate association fibre bundles during every step of a surgical approach.
Francesco Latini, Mats Ryttlefors
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Isointense infant brain MRI segmentation with a dilated convolutional neural network [PDF]
, 2017 Quantitative analysis of brain MRI at the age of 6 months is difficult because of the limited contrast between white matter and gray matter. In this study, we use a dilated triplanar convolutional neural network in combination with a non-dilated 3D ...
Moeskops, Pim, Pluim, Josien P. W.
core +8 more sources
Investigating White Matter Lesion Load, Intrinsic Functional Connectivity, and Cognitive Abilities in Older Adults [PDF]
, 2020 Changes to the while matter of the brain disrupt neural communication between spatially distributed brain regions and are associated with cognitive changes in later life.
Kantarovich, Karin
core