Results 11 to 20 of about 3,212,115 (185)
Therapeutic Advances in Neurological Disorders, 2012 White matter dementia (WMD) is a syndrome introduced in 1988 to highlight the potential of cerebral white matter disorders to produce cognitive loss of sufficient severity to qualify as dementia. Neurologists have long understood that such a syndrome can
Christopher M. Filley
doaj +3 more sources
White Matter-Gray Matter Correlation Analysis Based on White Matter Functional Gradient
Brain SciencesBackground: The spontaneous fluctuations in functional magnetic resonance imaging (fMRI) signals of the brain’s gray matter (GM) have been interpreted as representations of neural activity variations.
Zhengjie Li +5 more
doaj +2 more sources
The role of white matter myelin in structural-functional network coupling [PDF]
Communications BiologyThe brain is a complex network of neuronal populations interconnected by white matter tracts. The composition of these white matter connections (SC) shapes inter-regional signaling dynamics giving rise to spatial patterns of synchronous functional ...
Mark C. Nelson +6 more
doaj +2 more sources
White matter changes underlie hypertension-related cognitive decline in older adults
NeuroImage: Clinical, 2023 Hypertension has been well recognized as a risk factor for cognitive impairment and dementia. Although the underlying mechanisms of hypertension-affected cognitive deterioration are not fully understood, white matter changes (WMCs) seem to play an ...
Zilin Li +4 more
doaj +1 more source
Regional vulnerability of brain white matter in vanishing white matter
Acta Neuropathologica Communications, 2023 Vanishing white matter (VWM) is a leukodystrophy that primarily manifests in young children. In this disease, the brain white matter is differentially affected in a predictable pattern with telencephalic brain areas being most severely affected, while ...
Jodie H.K. Man +7 more
doaj +1 more source
What's the Matter? White Matter? [PDF]
Neuron, 2000 Although many children acquire reading skills rapidly with some formal training, for others learning to read is among the most difficult challenges they face in the first few years at school. The reasons for these large individual differences in skill acquisition are still obscure, with the relative contribution of biological and environmental factors ...
Zeffiro, Thomas, Eden, Guinevere
openaire +2 more sources
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Annals of Clinical and Translational Neurology, 2020 Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration ...
Nicole I. Wolf +15 more
doaj +1 more source
Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]
PLoS ONE, 2015 Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos +3 more
doaj +1 more source
White Matter Abnormalities in Patients with Treatment-Resistant Genetic Generalized Epilepsies. [PDF]
, 2016 BACKGROUND Genetic generalized epilepsies (GGEs) are associated with microstructural brain abnormalities that can be evaluated with diffusion tensor imaging (DTI). Available studies on GGEs have conflicting results.
Allendorfer, Jane B +7 more
core +2 more sources
Disconnected aging: cerebral white matter integrity and age-related differences in cognition. [PDF]
, 2014 Cognition arises as a result of coordinated processing among distributed brain regions and disruptions to communication within these neural networks can result in cognitive dysfunction.
Bennett, IJ, Madden, DJ
core +1 more source