Results 11 to 20 of about 5,007,319 (296)

Regional vulnerability of brain white matter in vanishing white matter

Acta Neuropathologica Communications, 2023
Vanishing white matter (VWM) is a leukodystrophy that primarily manifests in young children. In this disease, the brain white matter is differentially affected in a predictable pattern with telencephalic brain areas being most severely affected, while ...
Jodie H.K. Man, Charlotte A.G.H. van Gelder, Marjolein Breur, Douwe Molenaar, Truus Abbink, Maarten Altelaar, Marianna Bugiani, Marjo S. van der Knaap   +7 more
doaj   +8 more sources

White matter dementia [PDF]

Therapeutic Advances in Neurological Disorders, 2012
White matter dementia (WMD) is a syndrome introduced in 1988 to highlight the potential of cerebral white matter disorders to produce cognitive loss of sufficient severity to qualify as dementia. Neurologists have long understood that such a syndrome can
Christopher M. Filley
doaj   +3 more sources

Vanishing white matter disease

Paediatria Croatica, 2009
Vanishing White Matter Disease (VWMD) is one of the most prevalent inherited white matter disorders in childhood, with a large variety in the age of onset and rate of progression. The classical and most common type shows its onset between the ages of 2 and 6 years in children with initially normal motor and mental development.
Mejaski-Bosnjak, V., Dakovic, I., Scheper, G.C., van der Knaap, M.S., Grmoja, T., Gojmerac, T.   +5 more
openaire   +5 more sources

White Matter-Gray Matter Correlation Analysis Based on White Matter Functional Gradient

Brain Sciences
Background: The spontaneous fluctuations in functional magnetic resonance imaging (fMRI) signals of the brain’s gray matter (GM) have been interpreted as representations of neural activity variations.
Zhengjie Li, Jiajun Liu, Jianhui Zheng, Luying Li, Ying Fu, Zhipeng Yang   +5 more
doaj   +3 more sources

White matter changes underlie hypertension-related cognitive decline in older adults

NeuroImage: Clinical, 2023
Hypertension has been well recognized as a risk factor for cognitive impairment and dementia. Although the underlying mechanisms of hypertension-affected cognitive deterioration are not fully understood, white matter changes (WMCs) seem to play an ...
Zilin Li, Wenxiao Wang, Feng Sang, Zhanjun Zhang, Xin Li   +4 more
doaj   +1 more source

What's the Matter? White Matter? [PDF]

Neuron, 2000
Although many children acquire reading skills rapidly with some formal training, for others learning to read is among the most difficult challenges they face in the first few years at school. The reasons for these large individual differences in skill acquisition are still obscure, with the relative contribution of biological and environmental factors ...
Zeffiro, Thomas, Eden, Guinevere
openaire   +2 more sources

Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction

Annals of Clinical and Translational Neurology, 2020
Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration ...
Nicole I. Wolf, Marjolein Breur, Bonnie Plug, Shanice Beerepoot, Aimee S. R. Westerveld, Diane F. vanRappard, Sharon I. deVries, Maarten H. P. Kole, Adeline Vanderver, Marjo S. van derKnaap, Caroline A. Lindemans, Peter M. vanHasselt, Jaap J. Boelens, Ulrich Matzner, Volkmar Gieselmann, Marianna Bugiani   +15 more
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The Microvasculature of the Cerebral White Matter: Arteries of the Subcortical White Matter [PDF]

Journal of Neuropathology & Experimental Neurology, 2003
The microvascular architecture of the human cerebral subcortical white matter was studied. Most of the subcortical arteries ran straight through the cortex, but upon entering the white matter, they began to coil, loop, and spiral. Vascular stains showed wide spaces between the adventitial sheaths and blood vessels. The blood vessels coiled, looped, and
Hiroko, Nonaka, Michio, Akima, Tsutomu, Hatori, Tadashi, Nagayama, Zean, Zhang, Fumie, Ihara   +5 more
openaire   +2 more sources

Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]

PLoS ONE, 2015
Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos, Pim Klarenbeek, Robert J van Oostenbrugge, Julie Staals   +3 more
doaj   +1 more source

White matter damage and cognitive impairment after traumatic brain injury [PDF]

, 2010
White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent.
Powell, Jane Hilary, Leech, R, K. M. Kinnunen, Counsell, Serena Jane; id_orcid, Bonnelle, V., Bonnelle, V, Sharp, D. J., Kinnunen, K. M., Hawkins, Peter Charlie; id_orcid, Patel, Maneesh Chandrakant, Patel, MC, M. C. Patel, Sharp, David James, Greenwood, Richard, D. J. Sharp, Hawkins, PC, Leech, R., Patel, M. C., Powell, Jane H., Greenwood, R, J. H. Powell, Counsell, S. J., Sharp, DJ, P. C. Hawkins, Counsell, SJ, Powell, JH, R. Greenwood, Kinnunen, KM, R. Leech, Bonnelle, Valerie, Leech, Robert, V. Bonnelle, Kinnunen, Kirsi Maria, Hawkins, R. C., S. J. Counsell   +34 more
core   +1 more source