Results 31 to 40 of about 5,567,921 (295)

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

Neural Regeneration Research, 2021
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly.
Yuexian Cui, Xuelian Jin, Jun Young Choi, Byung Gon Kim   +3 more
doaj   +1 more source

Characterization of White Matter Hyperintensities in Large-Scale MRI-Studies

Frontiers in Neurology, 2019
Background: White matter hyperintensities of presumed vascular origin (WMH) are a common finding in elderly people and a growing social malady in the aging western societies. As a manifestation of cerebral small vessel disease, WMH are considered to be a
Benedikt M. Frey, Marvin Petersen, Carola Mayer, Maximilian Schulz, Bastian Cheng, Götz Thomalla   +5 more
doaj   +1 more source

Obsessive compulsive symptom dimensions are linked to altered white-matter microstructure in a community sample of youth

Translational Psychiatry, 2022
Obsessive-compulsive symptoms (OCS) are common in school-aged children and predict the development of obsessive compulsive disorder (OCD). White-matter abnormalities have been described in OCD, but the white matter correlates of OCS in the developing ...
Rachael G. Grazioplene, Colin G. DeYoung, Michelle Hampson, Alan Anticevic, Christopher Pittenger   +4 more
doaj   +1 more source

Vanishing white matter disease

Paediatria Croatica, 2009
Vanishing White Matter Disease (VWMD) is one of the most prevalent inherited white matter disorders in childhood, with a large variety in the age of onset and rate of progression. The classical and most common type shows its onset between the ages of 2 and 6 years in children with initially normal motor and mental development.
Mejaski-Bosnjak, V., Dakovic, I., Scheper, G.C., van der Knaap, M.S., Grmoja, T., Gojmerac, T.   +5 more
openaire   +4 more sources

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Age-Related White Matter Changes

Journal of Aging Research, 2011
Age-related white matter changes (WMC) are considered manifestation of arteriolosclerotic small vessel disease and are related to age and vascular risk factors.
Yun Yun Xiong, Vincent Mok
doaj   +1 more source

Functional connectivity of white matter as a biomarker of cognitive decline in Alzheimer's disease.

PLoS ONE, 2020
ObjectiveIn vivo functional changes in white matter during the progression of Alzheimer's disease (AD) have not been previously reported. Our objectives are to measure changes in white matter functional connectivity (FC) in an elderly population ...
Yurui Gao, Anirban Sengupta, Muwei Li, Zhongliang Zu, Baxter P Rogers, Adam W Anderson, Zhaohua Ding, John C Gore, Alzheimer’s Disease Neuroimaging Initiative   +8 more
doaj   +1 more source

Association between gray/white matter contrast and white matter microstructural alterations in medication-naïve obsessive–compulsive disorder

NeuroImage: Clinical, 2022
Intracortical myelin is involved in speeding and synchronizing neural activity of the cerebral cortex and has been found to be disrupted in various psychiatric disorders. However, its role in obsessive–compulsive disorder (OCD) has remained unknown.
Qihui Niu, Jianyu Li, Lei Yang, Zitong Huang, Mingmin Niu, Xueqin Song, Yuanchao Zhang, Youhui Li   +7 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Brain White Matter: A Substrate for Resilience and a Substance for Subcortical Small Vessel Disease

Brain Sciences, 2019
Age-related brain white matter disease is a form of small vessel disease (SVD) that may be associated with lacunar and other small subcortical infarcts, cerebral microbleeds, and perivascular spaces.
Farzaneh A. Sorond, Philip B. Gorelick
doaj   +1 more source