Results 1 to 10 of about 4,653,684 (196)

Analysis of Risk Factors for White Matter Hyperintensity in Older Adults without Stroke

Brain Sciences, 2023
Background: White matter hyperintensity (WMH) is prevalent in older adults aged 60 and above. A large proportion of people with WMH have not experienced stroke and little has been reported in the literature.
Kai Zheng, Zheng Wang, Xi Chen, Jiajie Chen, Yu Fu, Qin Chen   +5 more
doaj   +4 more sources

Distinct spatiotemporal patterns of white matter hyperintensity progression [PDF]

Nature Communications
White matter hyperintensity, a key imaging biomarker for brain health, has prognostic implications for stroke. Using a multicenter MRI dataset of 9179 stroke patients plus the UK Biobank (n = 36,210 low/high risk controls), we employ Subtype and Stage ...
Jinyong Chung, Gilsoon Park, Wi-Sun Ryu, Dawid Schellingerhout, Hang-Rai Kim, Dong-Seok Gwak, Elizabeth Haddad, Neda Jahanshad, Beom Joon Kim, Keun-Sik Hong, Hyerin Oh, Sang-Wuk Jeong, Joon-Tae Kim, Man Seok Park, Kang-Ho Choi, Kyungbok Lee, Tai Hwan Park, Sang-Soon Park, Jong-Moo Park, Kyusik Kang, Kyung-Ho Yu, Mi Sun Oh, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Jun Lee, Moon-Ku Han, Yong-Jin Cho, Byung-Chul Lee, Philip M. Bath, Joanna M. Wardlaw, Hee-Joon Bae, Hosung Kim, Dong-Eog Kim   +34 more
doaj   +3 more sources

The associations between bone mineral density and cerebral white matter hyperintensity in elderly stroke patients [PDF]

Precision and Future Medicine, 2018
Purpose Osteoporosis is an important senile disease and has significant relationship with ischemic stroke and cerebral small vessel disease (SVD).
Ji-Sun Kim, Minjik Kim, Sung Hoon Kang, Kyungmi Oh, Sangil Suh, Woo-Keun Seo   +5 more
doaj   +3 more sources

Progress of radiomics research on white matter hyperintensity lesions [PDF]

Frontiers in Neurology
White matter hyperintensity (WMH) is the core imaging hallmark of cerebral small vessel disease (CSVD). This phenomenon is closely related to nervous system damage, such as cognitive impairment, dementia and increased risk of stroke. However, traditional
Lin Du, Lieping Wang, Gang Shen, Min Zeng, Desheng Li, Weiguo Li   +5 more
doaj   +2 more sources

Red cell distribution width and cerebral white matter hyperintensity [PDF]

Scientific Reports
Red cell distribution width (RDW) is an indicator of red blood cell size heterogeneity and may reflect underlying chronic hypoxemia or inflammation. While RDW has been associated with the prognosis of various pulmonary and cardiovascular diseases, its ...
Ki-Woong Nam, Hyung-Min Kwon, Han-Yeong Jeong, Jin-Ho Park, Kyungha Min   +4 more
doaj   +2 more sources

Association of Low Blood Pressure with White Matter Hyperintensities in Elderly Individuals with Controlled Hypertension [PDF]

Journal of Stroke, 2020
Background and Purpose Both hypertension and hypotension increase cerebral white matter hyperintensities. However, the effects of hypotension in individuals with treated hypertension are unknown. We analyzed the association of low blood pressure with the
Jun Sung Kim, Subin Lee, Seung Wan Suh, Jong Bin Bae, Ji Hyun Han, Seonjeong Byun, Ji Won Han, Jae Hyoung Kim, Ki Woong Kim   +8 more
doaj   +1 more source

Automatic segmentation of white matter hyperintensities and correlation analysis for cerebral small vessel disease

Frontiers in Neurology, 2023
ObjectiveCerebral white matter hyperintensity can lead to cerebral small vessel disease, MRI images in the brain are used to assess the degree of pathological changes in white matter regions.
Bin Xu, Bin Xu, Xiaofeng Zhang, Congyu Tian, Wei Yan, Yuanqing Wang, Doudou Zhang, Doudou Zhang, Xiangyun Liao, Xiaodong Cai, Xiaodong Cai   +10 more
doaj   +1 more source

Brain White Matter Structure and Amyloid Deposition in Black and White Older Adults: The ARIC‐PET Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background White matter abnormalities are a common feature of aging and Alzheimer disease, and tend to be more severe among Black individuals. However, the extent to which white matter abnormalities relate to amyloid deposition, a marker of Alzheimer ...
Keenan A. Walker, Noah Silverstein, Yun Zhou, Timothy M. Hughes, Clifford R. Jack, David S. Knopman, A. Richey Sharrett, Dean F. Wong, Thomas H. Mosley, Rebecca F. Gottesman   +9 more
doaj   +1 more source

APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia

Alzheimer’s Research & Therapy, 2023
Background White matter hyperintensities, a neuroimaging marker of small-vessel cerebrovascular disease and apolipoprotein ε4 (APOE4) allele, are important dementia risk factors.
Ashwati Vipin, Dilip Kumar, See Ann Soo, Fatin Zahra Zailan, Yi Jin Leow, Chen Ling Koh, Adeline Su Lyn Ng, Kok Pin Ng, Nagaendran Kandiah   +8 more
doaj   +1 more source

Histologic Definition of Enhancing Core and FLAIR Hyperintensity Region of Glioblastoma, IDH-Wild Type: A Clinico-Pathologic Study on a Single-Institution Series

Brain Sciences, 2023
The extent of resection beyond the enhancing core (EC) in glioblastoma IDH-wild type (GBM, IDHwt) is one of the most debated topics in neuro-oncology. Indeed, it has been demonstrated that local disease recurrence often arises in peritumoral areas and ...
Giuseppe Broggi, Roberto Altieri, Valeria Barresi, Francesco Certo, Giuseppe Maria Vincenzo Barbagallo, Magda Zanelli, Andrea Palicelli, Gaetano Magro, Rosario Caltabiano   +8 more
doaj   +1 more source