Results 31 to 40 of about 4,653,684 (196)

Global and regional associations of smaller cerebral gray and white matter volumes with gait in older people. [PDF]

PLoS ONE, 2014
BACKGROUND: Gait impairments increase with advancing age and can lead to falls and loss of independence. Brain atrophy also occurs in older age and may contribute to gait decline. We aimed to investigate global and regional relationships of cerebral gray
Michele L Callisaya, Richard Beare, Thanh G Phan, Jian Chen, Velandai K Srikanth   +4 more
doaj   +1 more source

Construction and validation of a cerebral white matter hyperintensity probability map of older Koreans

NeuroImage: Clinical, 2021
Background and purpose: Although two white matter hyperintensity (WMH) probability maps of healthy older adults already exist, they have several limitations in representing the distribution of WMH in healthy older adults, especially Asian older adults ...
Jun Sung Kim, Subin Lee, Grace Eun Kim, Dae Jong Oh, Woori Moon, Jong Bin Bae, Ji Won Han, Seonjeong Byun, Seung Wan Suh, Yu Yong Choi, Kyu Yeong Choi, Kun Ho Lee, Jae Hyoung Kim, Ki Woong Kim   +13 more
doaj   +1 more source

Migraine and white matter hyperintensities [PDF]

Neurology, 2013
OBJECTIVE: Migraine is associated with white matter hyperintensities (WMH) cross-sectionally, but its effect on WMH progression is uncertain. METHODS: Participants in the Atherosclerosis Risk in Communities cohort study (n = 10,924) completed a standardized headache questionnaire between 1993 and 1995.
Ali G, Hamedani, Kathryn M, Rose, B Lee, Peterlin, Thomas H, Mosley, Laura H, Coker, Clifford R, Jack, David S, Knopman, Alvaro, Alonso, Rebecca F, Gottesman   +8 more
openaire   +2 more sources

Changes in the MRI brain picture associated with newly diagnosed asymptomatic arterial hypertension

Анналы клинической и экспериментальной неврологии, 2017
ntroduction.Arterial hypertension (AH) is the major modified riskfactor for brain injury. Clarification of the brain changes and themechanisms of their development during the asymptomatic stagewill ensure better results in the prevention of AH ...
L. A. Dobrynina, E. V. Gnedovskaya, A. N. Sergeeva, M. V. Krotenkova, M. A. Piradov   +4 more
doaj   +1 more source

Data of White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes

, 2023
Anonymized MRI data and white matter hyperintensity (WMH) segmentations from the Utrecht Vascular Cognitive Impairment Study Group. Questions can be addressed to the Utrecht Vascular Cognitive Impairment Study Group Data Access Committee.
Kuijf, Hugo, Biessels, Geert Jan
core   +2 more sources

White matter hyperintensities among older adults are associated with futile increase in frontal activation and functional connectivity during spatial search. [PDF]

PLoS ONE, 2015
The mechanisms by which aging and other processes can affect the structure and function of brain networks are important to understanding normal age-related cognitive decline.
Samuel N Lockhart, Steven J Luck, Joy Geng, Laurel Beckett, Elizabeth A Disbrow, Owen Carmichael, Charles DeCarli   +6 more
doaj   +1 more source

White matter hyperintensities and dynamics of postural control [PDF]

Magnetic Resonance Imaging, 2009
White matter hyperintensities (WMHs) on MRI have been associated with age, cardiovascular risk factors and falls in the elderly. This study evaluated the relationship between WMHs and dynamics of postural control in older adults without history of falls.We studied 76 community-living subjects without history of falls (age 64.5+/-7.3 years).
Novak, Vera, Haertle, Mareile, Zhao, Peng, Hu, Kun, Munshi, Medha, Novak, Peter, Abduljalil, Amir, Alsop, David   +7 more
openaire   +4 more sources

Cognitive reserve and midlife vascular risk: Cognitive and clinical outcomes

Annals of Clinical and Translational Neurology, 2020
Objective Examine whether cognitive reserve moderates the association of 1) vascular risk factors and 2) white matter hyperintensity burden with risk of clinical progression and longitudinal cognitive decline.
Anja Soldan, Corinne Pettigrew, Yuxin Zhu, Mei‐Cheng Wang, Rebecca F. Gottesman, Charles DeCarli, Marilyn Albert, the BIOCARD Research Team   +7 more
doaj   +1 more source

A Postmortem MRI Study of Cerebrovascular Disease and Iron Content at End-Stage of Fragile X-Associated Tremor/Ataxia Syndrome

Cells, 2023
Brain changes at the end-stage of fragile X-associated tremor/ataxia syndrome (FXTAS) are largely unknown due to mobility impairment. We conducted a postmortem MRI study of FXTAS to quantify cerebrovascular disease, brain atrophy and iron content, and ...
Jun Yi Wang, Gerard J. Sonico, Maria Jimena Salcedo-Arellano, Randi J. Hagerman, Veronica Martinez-Cerdeno   +4 more
doaj   +1 more source

White Matter Hyperintensities and Working Memory: An Explorative Study [PDF]

Aging, Neuropsychology, and Cognition, 2008
White matter hyperintensities (WMH) are commonly observed in elderly people and may have the most profound effect on executive functions, including working memory. Surprisingly, the Digit Span backward, a frequently employed working memory task, reveals no association with WMH. In the present study, it was investigated whether more detailed analyses of
Oosterman, J.M., Harten, B. van, Weinstein, H.C., Scheltens, P., Sergeant, J.A., Scherder, E.J.A.   +5 more
openaire   +3 more sources