Results 31 to 40 of about 24,272 (299)

Imaging of Angiogenesis in White Matter Hyperintensities

Journal of the American Heart Association, 2023
Background White matter hyperintensities (WMHs) are areas of increased signal intensity on T2‐weighted magnetic resonance imaging (MRI). WMH penumbra may be a potential target for early intervention in WMHs. We explored the relationship between angiogenesis and WMH penumbra in patients with WMHs.
Lingling Ding, Bo Hou, Jie Zang, Tong Su, Feng Feng, Zhaohui Zhu, Bin Peng   +6 more
openaire   +3 more sources

Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]

PLoS ONE, 2015
Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos, Pim Klarenbeek, Robert J van Oostenbrugge, Julie Staals   +3 more
doaj   +1 more source

Independent and additive contribution of white matter hyperintensities and Alzheimer’s disease pathology to basal forebrain cholinergic system degeneration

NeuroImage: Clinical, 2023
Objectives: Degeneration of the cholinergic basal forebrain nuclei (CBFN) system has been studied extensively in Alzheimer's disease (AD). White matter hyperintensities are a hallmark of aging as well as a common co-morbidity of AD, but their ...
Christine Kindler, Neeraj Upadhyay, Zeynep Bendella, Franziska Dorn, Vera C. Keil, Gabor C. Petzold   +5 more
doaj   +1 more source

Fluid-attenuated inversion recovery magnetic resonance imaging textural features as sensitive markers of white matter damage in midlife adults [PDF]

, 2022
White matter hyperintensities are common radiological findings in ageing and a typical manifestation of cerebral small vessel disease. White matter hyperintensity burden is evaluated by quantifying their volume; however, subtle changes in the white ...
Ritchie, Karen, O’Brien, J.T., Ritchie, K., Ritchie, C.W., Dounavi, Maria-Eleni, Ritchie, Craig W., Low, Audrey, Low, A., Muniz-Terrera, G., O’Brien, John T., Markus, H.S., Su, Li, Dounavi, M.-E., O'Brien, John T., Muniz-Terrera, Graciela, Markus, Hugh S., Su, L.   +16 more
core   +1 more source

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. [PDF]

, 2010
Objectives: To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death. Design: Systematic review and meta-analysis.
Debette, S, Markus, H.S., Markus, H S, S. Debette, Debette, Stéphanie, H. S. Markus, Markus, HS   +6 more
core   +1 more source

White Matter Hyperintensities and Medication Adherence [PDF]

Biological Research For Nursing, 2008
White matter hyperintensities (WMH) are associated with hypertension, age, and cognitive function, but the association between WMH and medication adherence has not been examined. The intent of this investigation was to consider the potential implications of hypertension-related brain morphological changes on medication adherence ...
Kathleen C, Insel, Sheryl L, Reminger, Chao-Pin, Hsiao   +2 more
openaire   +2 more sources

Regional distribution of white matter hyperintensities in vascular dementia, Alzheimer's disease and healthy aging [PDF]

, 2004
Background: White matter hyperintensities (WMH) on MRI scans indicate lesions of the subcortical fiber system. The regional distribution of WMH may be related to their pathophysiology and clinical effect in vascular dementia (VaD), Alzheimer's disease ...
Zebuhr, Y, Teipel, S. J., Möller, H. J., Zebuhr, Y., Leinsinger, G., Teipel, SJ, Gootjes, Liselotte, Wismüller, A., Hampel, H, Teipel, S.J, Scheltens, P, Schwarz, R., Scheltens, P., Möller, Hans-Jürgen, Gootjes, L., Wismuller, A, Hampel, H., Moller, HJ, Möller, H.-J., Leinsinger, G, Schwarz, R   +20 more
core   +1 more source

Impact of white matter hyperintensity location on depressive symptoms in memory-clinic patients: a lesion–symptom mapping study [PDF]

, 2019
BACKGROUND: We investigated the association between white matter hyperintensity location and depressive symptoms in a memoryclinic population using lesion–symptom mapping.
Prins, Niels D., Prins, ND, Kuijf, HJ, Biessels, GJ, Scheltens, P, Barkhof, F, Biessels, Geert Jan, Weaver, NA, van der Flier, Wiesje M., Weaver, Nick A., Leeuwis, Anna E., Exalto, Lieza G., Hooghiemstra, Astrid M., Leeuwis, AE, Hooghiemstra, AM, TRACE-VCI study group, van der Flier, WM, Biesbroek, J. Matthijs, Kuijf, Hugo J., Barkhof, Frederik, Biesbroek, JM, Exalto, LG, Scheltens, Philip   +22 more
core   +3 more sources

Correlations among peripheral blood markers, white matter hyperintensity, and cognitive function in patients with non-disabling ischemic cerebrovascular events

Frontiers in Aging Neuroscience, 2022
BackgroundBoth inflammation and cerebral white matter injury are closely associated with vascular cognitive impairment (VCI). The aim of this study was to analyze the correlation between peripheral serological markers, white matter injury, and cognitive ...
Binghan Li, Bingying Du, Zhengsheng Gu, Chenghao Wu, Yuhao Tan, Chenrui Song, Yawen Xu, Ge Yin, Xin Gao, Weisen Wang, Xu Sun, Xiaoying Bi   +11 more
doaj   +1 more source

Quantifying white matter hyperintensity and brain volumes in heterogeneous clinical and low-field portable MRI [PDF]

, 2023
Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis.
Kirsch, John, DeHavenon, Adam, Sorby-Adams, Annabel, Guo, Jennifer, Payabavash, Sam, Young, Sean I., Cerri, Stefano, Rosen, Matthew S., Kimberly, W. Taylor, Goebl, Philipp, Sheth, Kevin N., Sze, Gordon, Liu, Peirong, Billot, Benjamin, Wu, Jiaming, Strisciuglio, Nicola; id_orcid, Laso, Pablo, Mateen, Farrah, Puonti, Oula, Eshaghi, Arman, Iglesias, Juan Eugenio, Wolterink, Jelmer M.; id_orcid, Li, Hongwei, Barkhof, Frederik   +23 more
core   +1 more source