Venous Collagenosis as Pathogenesis of White Matter Hyperintensity
ObjectivePeriventricular white matter hyperintensities (pvWMHs) are commonly observed on MRI in older individuals and are associated with cognitive and motor decline. The etiology of pvWMH remains unknown. Venous collagenosis has been implicated, which may also interfere with perivascular fluid flow leading to dilation of perivascular spaces (PVS ...
David Lahna +10 more
openaire +2 more sources
Quantifying white matter hyperintensity and brain volumes in heterogeneous clinical and low-field portable MRI [PDF]
Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis.
Kirsch, John +23 more
core +1 more source
White matter hyperintensity volume in pre-diabetes, diabetes and normoglycemia
Introduction As white matter hyperintensities (WMHs) of the brain are associated with an increased risk of stroke, cognitive decline, and depression, elucidating the associated risk factors is important.
Susanne Rospleszcz +15 more
doaj +1 more source
Estimated trajectories of functional status, by amount of white matter hyperintensity.
WMHV, white matter hyperintensity volume.
Ying-Kuen Cheung (4686259) +6 more
core +1 more source
Fluid-attenuated inversion recovery magnetic resonance imaging textural features as sensitive markers of white matter damage in midlife adults [PDF]
White matter hyperintensities are common radiological findings in ageing and a typical manifestation of cerebral small vessel disease. White matter hyperintensity burden is evaluated by quantifying their volume; however, subtle changes in the white ...
Ritchie, Karen +24 more
core +3 more sources
Swallowing Impairment in Patients with Cerebral Small Vessel Disease
Background: Dysphagia is the important complication related to cerebral small vessel disease (CSVD) including lacunar infarcts (LIs), white matter hyperintensity (WMH), cerebral microbleeds (CMBs) and perivascular spaces (PVS).
Misa Seki +4 more
doaj +1 more source
White mater hyperintensities and microplastics
Motivation: White matter hyperintensities are abnormalities that appear in MRI scans of living patients but are not apparent in MRI post-mortem. Goal(s): Our goal is to understand the cellular/biological basis of white matter hyperintensities. Approach: We aligned post-mortem MR scans with those collected antemortem preformed histopathology and pyrGC ...
Elaine L. Bearer +3 more
openaire +2 more sources
Cerebral White Matter Hyperintensity as a Healthcare Quotient [PDF]
To better understand the risk factors and optimal therapeutic strategies of cerebral white matter hyperintensity (WMH), we examined a large population of adults with and without various vascular risk factors (VRFs) or vascular risk conditions (VRCs), such as hypertension (HT), diabetes mellitus (DM), and dyslipidemia (DLP), including the comorbidities.
Kaechang Park +8 more
openaire +2 more sources
DEWS (DEep White matter hyperintensity Segmentation framework): A fully automated pipeline for detecting small deep white matter hyperintensities in migraineurs [PDF]
Migraineurs show an increased load of white matter hyperintensities (WMHs) and more rapid deep WMH progression. Previous methods for WMH segmentation have limited efficacy to detect small deep WMHs.
Jihoon Cha +6 more
core +1 more source
Waxing and waning of white matter hyperintensities
Small vessel disease (SVD) manifests in myriad ways, most prominently as white matter hyperintensities (WMH).1,2 By the age of 60 years, virtually every healthy individual has evidence of WMH,3 and those with ischemic stroke have even more extensive changes.4 Cerebral ischemic injury from occlusion or stenosis of deep penetrating arteries due to ...
de Leeuw, F.E. +2 more
openaire +4 more sources

