Global and regional associations of smaller cerebral gray and white matter volumes with gait in older people. [PDF]
PLoS ONE, 2014 BACKGROUND: Gait impairments increase with advancing age and can lead to falls and loss of independence. Brain atrophy also occurs in older age and may contribute to gait decline. We aimed to investigate global and regional relationships of cerebral gray
Michele L Callisaya +4 more
doaj +1 more source
Clinical, laboratory, and white matter hyperintensity profiles of the study population.
, 2021 Clinical, laboratory, and white matter hyperintensity profiles of the study population.
Hyun-Woo Nam (3056094) +3 more
core +1 more source
Migraine and white matter hyperintensities [PDF]
Neurology, 2013 OBJECTIVE: Migraine is associated with white matter hyperintensities (WMH) cross-sectionally, but its effect on WMH progression is uncertain. METHODS: Participants in the Atherosclerosis Risk in Communities cohort study (n = 10,924) completed a standardized headache questionnaire between 1993 and 1995.
Ali G, Hamedani +8 more
openaire +2 more sources
DEWS (DEep White matter hyperintensity Segmentation framework): A fully automated pipeline for detecting small deep white matter hyperintensities in migraineurs [PDF]
, 2018 Migraineurs show an increased load of white matter hyperintensities (WMHs) and more rapid deep WMH progression. Previous methods for WMH segmentation have limited efficacy to detect small deep WMHs.
Jihoon Cha +6 more
core +3 more sources
Changes in the MRI brain picture associated with newly diagnosed asymptomatic arterial hypertension
Анналы клинической и экспериментальной неврологии, 2017 ntroduction.Arterial hypertension (AH) is the major modified riskfactor for brain injury. Clarification of the brain changes and themechanisms of their development during the asymptomatic stagewill ensure better results in the prevention of AH ...
L. A. Dobrynina +4 more
doaj +1 more source
NeuroImage: Clinical, 2021 Background and purpose: Although two white matter hyperintensity (WMH) probability maps of healthy older adults already exist, they have several limitations in representing the distribution of WMH in healthy older adults, especially Asian older adults ...
Jun Sung Kim +13 more
doaj +1 more source
White matter hyperintensities among older adults are associated with futile increase in frontal activation and functional connectivity during spatial search. [PDF]
PLoS ONE, 2015 The mechanisms by which aging and other processes can affect the structure and function of brain networks are important to understanding normal age-related cognitive decline.
Samuel N Lockhart +6 more
doaj +1 more source
White matter hyperintensities and dynamics of postural control [PDF]
Magnetic Resonance Imaging, 2009 White matter hyperintensities (WMHs) on MRI have been associated with age, cardiovascular risk factors and falls in the elderly. This study evaluated the relationship between WMHs and dynamics of postural control in older adults without history of falls.We studied 76 community-living subjects without history of falls (age 64.5+/-7.3 years).
Novak, Vera +7 more
openaire +4 more sources
Cognitive reserve and midlife vascular risk: Cognitive and clinical outcomes
Annals of Clinical and Translational Neurology, 2020 Objective Examine whether cognitive reserve moderates the association of 1) vascular risk factors and 2) white matter hyperintensity burden with risk of clinical progression and longitudinal cognitive decline.
Anja Soldan +7 more
doaj +1 more source
Intranasal Insulin Reduces White Matter Hyperintensity Progression in Association with Improvements in Cognition and CSF Biomarker Profiles in Mild Cognitive Impairment and Alzheimer’s Disease [PDF]
, 2021 BackgroundIntranasally administered insulin has shown promise in both rodent and human studies in Alzheimer's disease; however, both effects and mechanisms require elucidation.ObjectiveWe assessed the effects of intranasally administered insulin on white
Aisen, P +6 more
core +1 more source