Results 61 to 70 of about 24,272 (299)

Research progress on the relationship between white matter hyperintensity and cognitive impairment [PDF]

, 2023
White matter hyperintensity （WMH） is one of the imaging markers of cerebral small vessel disease （CSVD）. Recent studies have found certain relationship between WMH and cognitive impairment.
Zhao Dan, Lü Yan, Zhao Zhongyan, Wu Chanji, Xu Ruyan, Huang Shixiong
core   +1 more source

White Matter Hyperintensity Volume and Cerebral Perfusion in Older Individuals with Hypertension Using Arterial Spin-Labeling

, 2016
BACKGROUND AND PURPOSE: White matter hyperintensities of presumed vascular origin in elderly patients with hypertension may be part of a general cerebral perfusion deficit, involving not only the white matter hyperintensities but also the surrounding ...
Caan, M. W. A., van Dalen, J. W., Steenwijk, M. D., Richard, E., Mutsaerts, H. J. M. M., Vrenken, H., van Gool, W. A., Majoie, C. B. L. M., Nederveen, A. J.   +8 more
core   +1 more source

Periventricular White Matter Hyperintensities and Functional Decline [PDF]

Journal of the American Geriatrics Society, 2017
Background/Objectives We previously showed that global brain white matter hyperintensity volume ( WMHV ) was associated with accelerated long‐term functional decline. The objective of the current study was to determine whether
Mandip S, Dhamoon, Ying-Kuen, Cheung, Ahmet, Bagci, Noam, Alperin, Ralph L, Sacco, Mitchell S V, Elkind, Clinton B, Wright   +6 more
openaire   +2 more sources

Exploration of heterogeneity in risk factors associated with imaging subtypes of white matter hyperintensities on fluid-attenuated inversion recovery magnetic resonance imaging

Frontiers in Neurology
BackgroundWhite matter hyperintensity (WMH), a critical early biomarker in cerebrovascular/neurodegenerative diseases, has traditionally been studied via global volume or subjective scoring, which overlooks its spatial heterogeneity, leading to ...
Yonglong Li, Xiufu Zhang, Haotian Wang, Linrong Jiang, Zhaoyang Gu, Jun Zhou, Ruipeng Liang   +6 more
doaj   +1 more source

Waxing and waning of white matter hyperintensities

Neurology, 2017
Small vessel disease (SVD) manifests in myriad ways, most prominently as white matter hyperintensities (WMH).1,2 By the age of 60 years, virtually every healthy individual has evidence of WMH,3 and those with ischemic stroke have even more extensive changes.4 Cerebral ischemic injury from occlusion or stenosis of deep penetrating arteries due to ...
de Leeuw, F.E., de Leeuw, F.E., Nichols, F., 3rd   +2 more
openaire   +4 more sources

Menopausal hot flashes and white matter hyperintensities [PDF]

Menopause, 2016
Hot flashes are classic symptoms of menopause. Emerging data link hot flashes to cardiovascular disease (CVD) risk, yet whether hot flashes are related to brain health is poorly understood. We examined the relationship between hot flashes (measured via physiologic monitor and self-report) and white matter hyperintensities (WMH) among midlife women ...
Rebecca C, Thurston, Howard J, Aizenstein, Carol A, Derby, Ervin, Sejdić, Pauline M, Maki   +4 more
openaire   +2 more sources

Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan

Annals of Clinical and Translational Neurology
Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition.
Jade Hannan, Sarah Newman‐Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman‐Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Nicholas Riccardi   +8 more
doaj   +1 more source

White matter hyperintensity, neurofilament light chain, and cognitive decline

Annals of Clinical and Translational Neurology, 2023
Objective We aimed to determine whether combining white matter hyperintensity (WMH) with neurofilament light chain (NfL) could provide additional information for cognition in older adults.
Anisa Dhana, Charles DeCarli, Klodian Dhana, Pankaja Desai, Robert S. Wilson, Denis A. Evans, Kumar B. Rajan   +6 more
doaj   +1 more source

Invited Article: An MRI-based approach to the diagnosis of white matter disorders

, 2009
Background: There are many different white matter disorders, both inherited and acquired, and consequently the diagnostic process is difficult. Establishing a specific diagnosis is often delayed at great emotional and financial costs.
van der Knaap, M.S., Schiffmann, R., Schiffmann, Raphael, van der Knaap, Marjo S.   +3 more
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Semisupervised white matter hyperintensities segmentation on MRI

Human Brain Mapping, 2022
AbstractThis study proposed a semisupervised loss function named level‐set loss (LSLoss) for cerebral white matter hyperintensities (WMHs) segmentation on fluid‐attenuated inversion recovery images. The training procedure did not require manually labeled WMH masks.
Fan Huang, Peng Xia, Varut Vardhanabhuti, Sai‐Kam Hui, Kui‐Kai Lau, Henry Ka‐Fung Mak, Peng Cao   +6 more
openaire   +2 more sources