Results 51 to 60 of about 4,653,684 (196)

Exploration of heterogeneity in risk factors associated with imaging subtypes of white matter hyperintensities on fluid-attenuated inversion recovery magnetic resonance imaging

Frontiers in Neurology
BackgroundWhite matter hyperintensity (WMH), a critical early biomarker in cerebrovascular/neurodegenerative diseases, has traditionally been studied via global volume or subjective scoring, which overlooks its spatial heterogeneity, leading to ...
Yonglong Li, Xiufu Zhang, Haotian Wang, Linrong Jiang, Zhaoyang Gu, Jun Zhou, Ruipeng Liang   +6 more
doaj   +1 more source

Menopausal hot flashes and white matter hyperintensities [PDF]

Menopause, 2016
Hot flashes are classic symptoms of menopause. Emerging data link hot flashes to cardiovascular disease (CVD) risk, yet whether hot flashes are related to brain health is poorly understood. We examined the relationship between hot flashes (measured via physiologic monitor and self-report) and white matter hyperintensities (WMH) among midlife women ...
Rebecca C, Thurston, Howard J, Aizenstein, Carol A, Derby, Ervin, Sejdić, Pauline M, Maki   +4 more
openaire   +2 more sources

Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan

Annals of Clinical and Translational Neurology
Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition.
Jade Hannan, Sarah Newman‐Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman‐Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Nicholas Riccardi   +8 more
doaj   +1 more source

A Fully Automated Visual Grading System for White Matter Hyperintensities of T2-Fluid Attenuated Inversion Recovery Magnetic Resonance Imaging

Journal of Integrative Neuroscience, 2023
Background: The Fazekas scale is one of the most commonly used visual grading systems for white matter hyperintensity (WMH) for brain disorders like dementia from T2-fluid attenuated inversion recovery magnetic resonance (MR) images (T2-FLAIRs). However,
ZunHyan Rieu, Regina EY Kim, Minho Lee, Hye Weon Kim, Donghyeon Kim, JeongHyun Yong, JiMin Kim, MinKyoung Lee, Hyunkook Lim, JeeYoung Kim   +9 more
doaj   +1 more source

Regional distribution of white matter hyperintensities in vascular dementia, Alzheimer's disease and healthy aging [PDF]

, 2004
Background: White matter hyperintensities (WMH) on MRI scans indicate lesions of the subcortical fiber system. The regional distribution of WMH may be related to their pathophysiology and clinical effect in vascular dementia (VaD), Alzheimer's disease ...
Zebuhr, Y, Teipel, S. J., Zebuhr, Y., Leinsinger, G., Teipel, SJ, Gootjes, Liselotte, Wismüller, A., Hampel, H, Teipel, S.J, Scheltens, P, Schwarz, R., Scheltens, P., Möller, Hans-Jürgen, Gootjes, L., Wismuller, A, Hampel, H., Moller, HJ, Möller, H.-J., Leinsinger, G, Schwarz, R   +19 more
core   +1 more source

White matter hyperintensity, neurofilament light chain, and cognitive decline

Annals of Clinical and Translational Neurology, 2023
Objective We aimed to determine whether combining white matter hyperintensity (WMH) with neurofilament light chain (NfL) could provide additional information for cognition in older adults.
Anisa Dhana, Charles DeCarli, Klodian Dhana, Pankaja Desai, Robert S. Wilson, Denis A. Evans, Kumar B. Rajan   +6 more
doaj   +1 more source

Coevolution of white matter hyperintensities and cognition in the elderly [PDF]

Neurology, 2012
To investigate the effects of baseline white matter hyperintensity (WMH) and rates of WMH extension and emergence on rate of change in cognition (episodic memory and executive function).A total of 150 individuals including cognitively normal elderly individuals and those with Alzheimer disease and mild cognitive impairment completed serial episodic ...
Pauline, Maillard, Owen, Carmichael, Evan, Fletcher, Bruce, Reed, Dan, Mungas, Charles, DeCarli   +5 more
openaire   +2 more sources

Association of P-wave terminal force in lead V₁ (PTFV₁) with white matter hyperintensity volume (n = 1172).

, 2018
Association of P-wave terminal force in lead V1 (PTFV1) with white matter hyperintensity volume (n = 1172).
Ralph L. Sacco (197580), Madeleine D. Hunter (5851277), Clinton B. Wright (676702), Hooman Kamel (839731), Marco R. Di Tullio (666456), Yeseon Park Moon (5851280), Jose Gutierrez (30524), Charles DeCarli (418756), Mitchell S. V. Elkind (507634)   +8 more
core   +1 more source

Periventricular White Matter Hyperintensities and Functional Decline [PDF]

Journal of the American Geriatrics Society, 2017
Background/Objectives We previously showed that global brain white matter hyperintensity volume ( WMHV ) was associated with accelerated long‐term functional decline. The objective of the current study was to determine whether
Mandip S, Dhamoon, Ying-Kuen, Cheung, Ahmet, Bagci, Noam, Alperin, Ralph L, Sacco, Mitchell S V, Elkind, Clinton B, Wright   +6 more
openaire   +2 more sources

WSO895707 Supplemental Material - Supplemental material for Normal-appearing white matter microstructural injury is associated with white matter hyperintensity burden in acute ischemic stroke

, 2019
Supplemental material, WSO895707 Supplemental Material for Normal-appearing white matter microstructural injury is associated with white matter hyperintensity burden in acute ischemic stroke by Mark R Etherton, Ona Wu, Anne-Katrin Giese and Natalia S ...
Mark R Etherton (8155041), Natalia S Rost (8155044), Ona Wu (464087), Anne-Katrin Giese (440558)   +3 more
core   +1 more source