Results 51 to 60 of about 24,272 (299)

White Matter Hyperintensities and Working Memory: An Explorative Study [PDF]

Aging, Neuropsychology, and Cognition, 2008
White matter hyperintensities (WMH) are commonly observed in elderly people and may have the most profound effect on executive functions, including working memory. Surprisingly, the Digit Span backward, a frequently employed working memory task, reveals no association with WMH. In the present study, it was investigated whether more detailed analyses of
Oosterman, J.M., Harten, B. van, Weinstein, H.C., Scheltens, P., Sergeant, J.A., Scherder, E.J.A.   +5 more
openaire   +3 more sources

A Postmortem MRI Study of Cerebrovascular Disease and Iron Content at End-Stage of Fragile X-Associated Tremor/Ataxia Syndrome

Cells, 2023
Brain changes at the end-stage of fragile X-associated tremor/ataxia syndrome (FXTAS) are largely unknown due to mobility impairment. We conducted a postmortem MRI study of FXTAS to quantify cerebrovascular disease, brain atrophy and iron content, and ...
Jun Yi Wang, Gerard J. Sonico, Maria Jimena Salcedo-Arellano, Randi J. Hagerman, Veronica Martinez-Cerdeno   +4 more
doaj   +1 more source

A deep learning algorithm for white matter hyperintensity lesion detection and segmentation

, 2021
Purpose: White matter hyperintensity (WMHI) lesions on MR images are an important indication of various types of brain diseases that involve inflammation and blood vessel abnormalities.
Zhuo, Zhizheng, Duan, Yunyun, Haller, Sven, Wang, Xiaoyang, Barkhof, Frederik, Zhang, Yajing, Liu, Yaou   +6 more
core   +1 more source

Progression of cerebral white matter hyperintensities is related to leucocyte gene expression [PDF]

, 2022
Cerebral white matter hyperintensities are an important contributor to ageing brain pathology. Progression in white matter hyperintensity volume is associated with cognitive decline and gait impairment.
Stamova, Boryana, Bradley P Ander, DeCarli, Charles, Charles DeCarli, Heather Hull, Frank R Sharp, Jickling, Glen C, Ander, Bradley P, Xinhua Zhan, Hull, Heather, Glen C Jickling, Boryana Stamova, Sharp, Frank R, Zhan, Xinhua   +13 more
core   +1 more source

Cerebral White Matter Hyperintensity as a Healthcare Quotient [PDF]

Journal of Clinical Medicine, 2019
To better understand the risk factors and optimal therapeutic strategies of cerebral white matter hyperintensity (WMH), we examined a large population of adults with and without various vascular risk factors (VRFs) or vascular risk conditions (VRCs), such as hypertension (HT), diabetes mellitus (DM), and dyslipidemia (DLP), including the comorbidities.
Kaechang Park, Kiyotaka Nemoto, Yoshinori Yamakawa, Fumio Yamashita, Keitaro Yoshida, Masashi Tamura, Atsushi Kawaguchi, Tetsuaki Arai, Makoto Sasaki   +8 more
openaire   +2 more sources

White matter hyperintensity volume in pre-diabetes, diabetes and normoglycemia

BMJ Open Diabetes Research & Care, 2021
Introduction As white matter hyperintensities (WMHs) of the brain are associated with an increased risk of stroke, cognitive decline, and depression, elucidating the associated risk factors is important.
Susanne Rospleszcz, Annette Peters, Margit Heier, Wolfgang Rathmann, Karl-Heinz Ladwig, Felix Hartmann, Fabian Bamberg, Roberto Lorbeer, Sergio Grosu, Christopher L Schlett, Franziska Galie, Sonja Selder, Sigrid Auweter, Katharina Mueller-Peltzer, Birgit B Ertl-Wagner, Sophia Stoecklein   +15 more
doaj   +1 more source

Linear regression analyses for factors associated with the log-transformed value of the white-matter hyperintensity volumes.

, 2021
Linear regression analyses for factors associated with the log-transformed value of the white-matter hyperintensity volumes.
Hyun-Woo Nam (3056094), Keun-Hwa Jung (168311), Woo-Jin Lee (846126), Yong-Seok Lee (83975)   +3 more
core   +1 more source

Coevolution of white matter hyperintensities and cognition in the elderly [PDF]

Neurology, 2012
To investigate the effects of baseline white matter hyperintensity (WMH) and rates of WMH extension and emergence on rate of change in cognition (episodic memory and executive function).A total of 150 individuals including cognitively normal elderly individuals and those with Alzheimer disease and mild cognitive impairment completed serial episodic ...
Pauline, Maillard, Owen, Carmichael, Evan, Fletcher, Bruce, Reed, Dan, Mungas, Charles, DeCarli   +5 more
openaire   +2 more sources

Swallowing Impairment in Patients with Cerebral Small Vessel Disease

Tokyo Women's Medical University Journal, 2020
Background: Dysphagia is the important complication related to cerebral small vessel disease (CSVD) including lacunar infarcts (LIs), white matter hyperintensity (WMH), cerebral microbleeds (CMBs) and perivascular spaces (PVS).
Misa Seki, Hiroshi Yoshizawa, Megumi Kubota, Sono Toi, Kazuo Kitagawa   +4 more
doaj   +1 more source

A deep learning algorithm for white matter hyperintensity lesion detection and segmentation [PDF]

, 2022
Purpose: White matter hyperintensity (WMHI) lesions on MR images are an important indication of various types of brain diseases that involve inflammation and blood vessel abnormalities.
Wang, X, Liu, Y, Zhuo, Z, Haller, S, Barkhof, F, Zhang, Y, Duan, Y   +6 more
core