Results 21 to 30 of about 4,472,600 (290)

White matter hyperintensities and hypobaric exposure [PDF]

Annals of Neurology, 2014
ObjectiveDemonstrate that occupational exposure to nonhypoxic hypobaria is associated with subcortical white matter hyperintensities (WMHs) on fluid‐attenuated inversion recovery magnetic resonance imaging (MRI).MethodsEighty‐three altitude chamber personnel (PHY), 105 U‐2 pilots (U2P), and 148 age‐ controlled and health‐matched doctorate degree ...
Stephen A, McGuire, Paul M, Sherman, S Andrea, Wijtenburg, Laura M, Rowland, Patrick M, Grogan, John H, Sladky, Andrew Y, Robinson, Peter V, Kochunov   +7 more
openaire   +2 more sources

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

Neural Regeneration Research, 2021
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly.
Yuexian Cui, Xuelian Jin, Jun Young Choi, Byung Gon Kim   +3 more
doaj   +1 more source

White Matter Hyperintensities and Medication Adherence [PDF]

Biological Research For Nursing, 2008
White matter hyperintensities (WMH) are associated with hypertension, age, and cognitive function, but the association between WMH and medication adherence has not been examined. The intent of this investigation was to consider the potential implications of hypertension-related brain morphological changes on medication adherence ...
Kathleen C, Insel, Sheryl L, Reminger, Chao-Pin, Hsiao   +2 more
openaire   +2 more sources

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. [PDF]

, 2010
Objectives: To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death. Design: Systematic review and meta-analysis.
Debette, S, Markus, H.S., Markus, H S, S. Debette, Debette, Stéphanie, H. S. Markus, Markus, HS   +6 more
core   +1 more source

Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life

Scientific Reports, 2021
Epigenetic imprinting is important for neurogenesis and brain function. Hippocampal volumes and brain hyperintensities in late life have been associated with early life circumstances. Epigenetic imprinting may underpin these associations. Methylation was
Marlene Lorgen-Ritchie, Alison D. Murray, Roger Staff, Anne C. Ferguson-Smith, Marcus Richards, Graham W. Horgan, Louise H. Phillips, Gwen Hoad, Chris McNeil, Antonio Ribeiro, Paul Haggarty   +10 more
doaj   +1 more source

Diabetes mellitus and white matter hyperintensity [PDF]

Geriatrics & Gerontology International, 2015
White matter hyperintensity (WMH) is a brain lesion detected as a high‐intensity area in magnetic resonance imaging T2 and fluid‐attenuated inversion recovery images, and it has been suggested that WMH reflects damage to small vessels in periventricular and subcortical areas. Although WMH has been linked to the incidence of stroke, more recently it has
Yoshiaki, Tamura, Atsushi, Araki
openaire   +2 more sources

Association of periodontitis with cerebral small vessel disease in hypertensive patients – A pilot study [PDF]

Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial
Objectives: Cerebral small vessel disease is a chronic, progressive disorder of arterioles, capillaries, and small veins supplying the brain’s white matter and deep structures of gray matter.
Tiago Pinto-Ribeiro, António Felino, Ricardo Faria-Almeida, Ana Monteiro, Jorge Polónia   +4 more
doaj   +1 more source

血管性帕金森综合征与帕金森病的临床特征及脑白质高信号差异性研究 Differences between Clinical Features and White Matter Hyperintensities between Vascular Parkinsonism and Parkinson′s Disease

Zhongguo cuzhong zazhi, 2023
目的 研究血管性帕金森综合征（vascular parkinsonism，VP）与帕金森病（Parkinson’s disease，PD）临床特征及脑白质高信号（white matter hyperintensities，WMH）的差异，为研究VP的发病机制提供一定的依据与思路。 方法 根据临床实际，健康受试者人数以1∶2的比例匹配，回顾性筛选符合入排标准的VP患者和年龄、性别、受教育程度与其相匹配的PD患者、健康志愿者，健康志愿者作为健康对照（healthy control，HC）组 ...
陈柏希，王婉仪，詹翠京，高玉元，聂坤，张玉虎，王丽娟
doaj   +1 more source

An improved algorithm of white matter hyperintensity detection in elderly adults

NeuroImage: Clinical, 2020
Automated segmentation of the aging brain raises significant challenges because of the prevalence, extent, and heterogeneity of white matter hyperintensities.
T Ding, AD Cohen, EE O’Connor, HT Karim, A Crainiceanu, J Muschelli, O Lopez, WE Klunk, HJ Aizenstein, R Krafty, CM Crainiceanu, DL Tudorascu   +11 more
doaj   +1 more source

Increased interstitial fluid in periventricular and deep white matter hyperintensities in patients with suspected idiopathic normal pressure hydrocephalus

Scientific Reports, 2021
Periventricular white matter changes are common in patients with idiopathic normal pressure hydrocephalus (iNPH) and considered to represent focally elevated interstitial fluid.
Alexander Rau, Marco Reisert, Elias Kellner, Jonas A. Hosp, Horst Urbach, Theo Demerath   +5 more
doaj   +1 more source