Results 21 to 30 of about 38,083 (208)

Basic and Translational Research on Proteinase-Activated Receptors: The Role of Thrombin Receptor in Cerebral Vasospasm in Subarachnoid Hemorrhage

Journal of Pharmacological Sciences, 2008
Cerebral vasospasm is one of the major complications of subarachnoid hemorrhage (SAH). The prevention and treatment of cerebral vasospasm thus plays a critical role in the management of SAH patients.
Yasutoshi Kai, Yoshihisa Maeda, Tomio Sasaki, Hideo Kanaide, Katsuya Hirano   +4 more
doaj   +1 more source

Minimal long-term neurobehavioral impairments after endovascular perforation subarachnoid hemorrhage in mice [PDF]

, 2017
Cognitive deficits are among the most severe and pervasive consequences of aneurysmal subarachnoid hemorrhage (SAH). A critical step in developing therapies targeting such outcomes is the characterization of experimentally-tractable pre-clinical models ...
Brody, David L, Fanizzi, Claudia, Gangolli, Mihika, Kummer, Terrance T, Sauerbeck, Andrew D, Zipfel, Gregory J   +5 more
core   +2 more sources

Pathogenic mechanisms and therapeutic implications of extracellular matrix remodelling in cerebral vasospasm

Fluids and Barriers of the CNS, 2023
Cerebral vasospasm significantly contributes to poor prognosis and mortality in patients with aneurysmal subarachnoid hemorrhage. Current research indicates that the pathological and physiological mechanisms of cerebral vasospasm may be attributed to the
Ziliang Hu, Xinpeng Deng, Shengjun Zhou, Chenhui Zhou, Menglu Shen, Xiang Gao, Yi Huang   +6 more
doaj   +1 more source

Symptomatic Cerebral Vasospasm after Surgical Ligation of Unruptured Aneurysms [PDF]

, 2009
Background Cerebral artery vasospasm accounts for the majority of delayed neurological deficits in ruptured aneurysm patients. We report two cases and review the literature of patients who developed symptomatic vasospasm after treatment for unruptured ...
Harrop, James, MD, Rosenwasser MD, Robert H.   +1 more
core   +2 more sources

Intra‐arterial infusion of fasudil hydrochloride to treat post‐traumatic cerebral vasospasm

Acute Medicine & Surgery, 2019
Background The effect of intra‐arterial infusion of fasudil hydrochloride in patients with post‐traumatic cerebral vasospasm remains unclear. Here we report a case of intra‐arterial infusion of fasudil hydrochloride for post‐traumatic cerebral vasospasm.
Tomoaki Murakami, Ryuichiro Kajikawa, Hajime Nakamura, Takeshi Nishida, Kazuhiro Yoshimura, Tomoyuki Yoshihara, Koichiro Tsuruzono, Akatsuki Wakayama, Haruhiko Kishima   +8 more
doaj   +1 more source

Can S100B predict cerebral vasospasms in patients suffering from subarachnoid hemorrhage?

Frontiers in Neurology, 2013
Background: Protein S100B has proven to be a useful biomarker for cerebral damages. Increased levels of serum and CSF S100B have been shown in patients suffering subarachnoid hemorrhage, severe head injury and stroke.
Moshgan eAmiri, Moshgan eAmiri, Ramona eAstrand, Bertil eRomner   +3 more
doaj   +1 more source

ERYTHROPOIETIN FOR THE TREATMENT OF SUBARACHNOID HEMORRAGE: A FEASIBLE INGREDIENT FOR A SUCCESS MEDICAL RECIPE [PDF]

, 2015
Subaracnhoid hemorrage (SAH) following aneurysm bleeding accounts for 6% to 8% of all cerebrovascular accidents. Althoug an aneurysm can be effectively managed by surgery or endovascular therapy, delayed cerebral ischemia is diagnosed in a high ...
A Gorio, A Jackowski, A Nagai, AL Siren, AM Murphy, AV Santhanam, AV Santhanam, BB Beleslin-Cokic, C Alafaci, C Lacombe, CC Tan, Concetta Alafaci, D Banerjee, D Burger, E Gao, E Morishita, F Fiordaliso, FA Sehba, FA Sehba, FH Bahlmann, Francesco Cappello, G Chen, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, G Grasso, Giovanni Grasso, Giovanni Tomasello, H Bao, H Cai, H Kertmen, H Ohashi, HH Marti, I Cervellini, JB Bederson, JB Springborg, JB Springborg, JM Schmidt, JW Fisher, K Chin, K Franke, K Jacobs, K Koshimura, K Rosenlof, KH Su, L Cherian, L Cherian, L Costa da, L Jia, L Sautina, L Wang, LJ Ignarro, LV d’Uscio, LV d’Uscio, M Bernaudin, M Brines, M Brines, M Brines, M Brines, M Buemi, M Digicaylioglu, M Digicaylioglu, M Duval, M Kawakami, M Leist, M Migliori, M Sabri, M Sakanaka, Marcello Noto, ML Brines, MO Arcasoy, MY Tseng, N Dorsch, N Urao, OM Martinez-Estrada, P Kim, PW McCormick, R Merla, R Wang, RG Carlini, RM Pluta, S Dang, S Genc, S Masuda, SE Juul, SS Najjar, ST Lee, TJ Delgado, W Jelkmann, W Jelkmann, W Li, WC Sessa, Y Sadamoto   +101 more
core   +1 more source

Vasospasm in Cerebral Inflammation

International Journal of Inflammation, 2014
All forms of cerebral inflammation as found in bacterial meningitis, cerebral malaria, brain injury, and subarachnoid haemorrhage have been associated with vasospasm of cerebral arteries and arterioles.
Michael Eisenhut
doaj   +1 more source

Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy [PDF]

, 2017
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes.
Olson, Michael F., Pajic, Marina, Rath, Nicola, Timpson, Paul, Vennin, Claire   +4 more
core   +1 more source

To Look Beyond Vasospasm in Aneurysmal Subarachnoid Haemorrhage. [PDF]

, 2014
Delayed cerebral vasospasm has classically been considered the most important and treatable cause of mortality and morbidity in patients with aneurysmal subarachnoid hemorrhage (aSAH).
Cossu, G., Daniel, R.T., Messerer, M., Oddo, M.   +3 more
core   +5 more sources