Non-contrast assessment of blood-brain barrier permeability to water in mice: An arterial spin labeling study at cerebral veins. [PDF]
Wei Z +9 more
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
The diagnostic value of susceptibility weighted imaging for cerebral venous malformation
Objective To assess the diagnostic value of susceptibility weighted imaging (SWI) for cerebral venous malformation. Methods The SWI features of 23 patients with cerebral venous malformation were analyzed retrospectively. The SWI images were compared with
Jun GUO +6 more
doaj
A rare case of coexistence of Wegener's granulomatosis and pulmonary tuberculosis with subsequent development of thrombosis of the cerebral veins. [PDF]
Rostami Z +7 more
europepmc +1 more source
Early-filling cerebral vein [PDF]
G J, Toffol, G, Gruener, M H, Naheedy
openaire +2 more sources
Stable radicals are attractive for photonic and quantum information technologies but are often limited by instability. We stabilize intrinsic radicals in graphene quantum dots via 2D polymerization of perylene derivatives, where bilayer defect confinement suppresses quenching (100–500 K).
Qin Xu +9 more
wiley +1 more source
Exploration of the correlation between superficial cerebral veins identified using susceptibility-weighted imaging findings and cognitive differences between sexes based on deep learning: a preliminary study. [PDF]
Wang Y +7 more
europepmc +1 more source
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen +7 more
wiley +1 more source
Evidence-Based Minireview: Should warfarin or a direct oral anticoagulant be used in patients presenting with thrombosis in the splanchnic or cerebral veins? [PDF]
Mathew C, Zumberg M.
europepmc +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source

