Results 91 to 100 of about 16,904 (216)

Evaluation and design of a novel drug delivery device for treating tumor-related cerebral edema [PDF]

, 2010
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p. 47-53).Tumor-related cerebral edema is a debilitating medical condition
Shair, Kamal A. (Kamal Abdo)
core  

Optic Chiasm and Bilateral Optic Nerve Oligodendroglioma in A 29‐Month‐Old German Shepherd

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To report the first documented case of high‐grade optic chiasm and nerve oligodendroglioma in a young dog and contribute to the comparative study of gliomas in humans and canines. Animal Studied A 29‐month‐old male intact German Shepherd.
Vienna M. Lunking, Rajdeep Multani, Devin Fussell, LaTisha N. Knight, Erin Keenihan, Danielle M. Meritet, Abigail R. Armwood, Annie Oh   +7 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Internalization of Exogenous Myelin by Oligodendroglia Promotes Lineage Progression

Glia, Volume 74, Issue 3, March 2026.
Oligodendroglia internalize extracellular myelin debris in vitro and in vivo. Internalized myelin modulates lipid metabolism and lipid droplet formation. Myelin‐derived signals promote oligodendroglial proliferation and lineage progression. ABSTRACT Oligodendrocytes, traditionally recognized for their role in central nervous system myelination, have ...
Carla Peiró‐Moreno, Juan Carlos Chara, Katy Marshall‐Phelps, Irune Ugarte‐Arakistain, Stefano Calovi, Rafael Gois De Almeida, María Domercq, Carlos Matute   +7 more
wiley   +1 more source

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo, Katherine Talpin, Bishal Harry, Uma H. Athale, Anthony K. C. Chan, Mihir D. Bhatt   +5 more
wiley   +1 more source

Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Choroid plexus (ChP) enlargement is a neuroimaging biomarker of neuroinflammation and neurodegeneration. However, evidence of ChP structural and perfusion alterations in long coronavirus disease (COVID) and their clinical relevance remains limited.
Huize Pang, Jennifer Frontera, Li Jiang, Chenyang Li, Allal Boutajangout, Zhe Sun, Ludovic Debure, Mobeena Ghuman, Alok Vedvyas, Arjun V. Masurkar, Thomas Wisniewski, Yulin Ge   +11 more
wiley   +1 more source

No Glymphatic Dysfunction in Trigeminal Neuralgia: A Preliminary Study

Brain and Behavior, Volume 16, Issue 2, February 2026.
In this study investigating cross‐sectional and longitudinal DTI‐ALPS changes in patients with trigeminal neuralgia, no DTI‐ALPS alterations were detected in trigeminal neuralgia patients. ABSTRACT Background Trigeminal neuralgia (TN) patients are at risk for glymphatic dysfunction due to their prolonged headaches and sleep disturbances.
Barış Genç, Kerim Aslan
wiley   +1 more source

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

Red Blood Cell Glycation Triggers In Vivo Cerebral Erythrophagocytosis in Adult Zebrafish in a Model Mimicking Hemorrhagic Stroke

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
In zebrafish, glycated RBCs promoted increased erythrophagocytic activity in microglia/macrophages, revealing a potential mechanism linking diabetes‐induced RBC glycation to exacerbated inflammatory responses and secondary damage after ICH. ABSTRACT Hemorrhagic stroke, particularly intracerebral hemorrhage (ICH), is a highly lethal subtype of stroke ...
Elena Morello, Philippe Rondeau, François Canonne‐Hergaux, Emmanuel Bourdon, Matthieu Bringart, Olivier Meilhac, David Couret, Nicolas Diotel   +7 more
wiley   +1 more source