Results 111 to 120 of about 16,904 (216)

Integrated ERK‐PKA‐YAP/TAZ‐SHH Signaling Orchestrates Cortical Radial Glia Identity and Lineage Diversification

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang   +13 more
wiley   +1 more source

Astrocyte–vascular interplay in Alzheimer's disease pathology: Novel insights into stage‐specific biomarkers and therapeutic targets

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION We examined how neurovascular and astrocytic response alter cognition in Alzheimer's disease (AD). METHODS Cognitive scores, biomarkers of AD and astrocytic activation, vascular factors, and brain structure data from 693 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants were analyzed using analysis of covariance ...
Zehu Sheng   +12 more
wiley   +1 more source

Surgical approach for left ventricular papillary fibroelastoma. [PDF]

open access: yesJ Cardiothorac Surg
Masuda T   +4 more
europepmc   +1 more source

The Clinical Characteristics and Treatment of Patients With Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP‐A): A Retrospective Study of 29 Patients

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
A retrospective analysis of clinical features, treatment, and outcome of 29 patients with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A). Cerebrospinal fluid (CSF) pressure, CSF nucleated cell count, CSF protein levels, CSF chloride, serum thyroid dysfunction, and abnormal blood cytokine levels correlated with disease severity but ...
Xuewei Yang   +6 more
wiley   +1 more source

Venetoclax‐Based Therapy for Early Relapse in Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report and Minireview

open access: yesCancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Refractory/relapsed acute myeloid leukemia (R/R‐AML) typically exhibits resistance to conventional chemotherapy, resulting in a poor overall therapeutic outcome. Salvage allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is the primary treatment option in such patients.
Yufeng Du   +6 more
wiley   +1 more source

Revisiting the role of histopathology in acute intracerebral hemorrhage: Detecting missed secondary lesions beyond neuroimaging. [PDF]

open access: yesSurg Neurol Int
Sofue T   +7 more
europepmc   +1 more source

Therapeutic Hypothermia Alleviates Hydrocephalus and Neurological Dysfunction Post Intraventricular Hemorrhage by Enhancing Drainage of Glymphatic‐Meningeal Lymphatic‐Deep Cervical Lymphatic System

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
TH is expected to be a novel therapeutic strategy for hydrocephalus and neurological dysfunction post IVH. TH alleviates hydrocephalus post IVH by enhancing drainage of the glymphatic‐meningeal lymphatic‐deep cervical lymphatic system, which is the connection between the central nervous system and peripheral lymphatic system.
Yijian Yang   +16 more
wiley   +1 more source

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