Results 101 to 110 of about 444,337 (305)

Automated Deep Learning Segmentation of Neonatal Cerebral Lateral Ventricles from Three-Dimensional Ultrasound Images

, 2021
Compared to two-dimensional (2D) ultrasound (US), three-dimensional (3D) US is a more sensitive alternative that can provide quantitative information for monitoring neonatal cerebral lateral ventricles.
Szentimrey, Zachary
core  

Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia : an ultrasound and MRI study [PDF]

, 2011
Transcranial Doppler is a widely used noninvasive technique for assessing cerebral artery blood flow. All previous high altitude studies assessing cerebral blood flow (CBF) in the field that have used Doppler to measure arterial blood velocity have ...
Hirani, Shashivadan P., Golay, Xavier, Imray, C. (Chris), Mark EG Edsell, Strycharczuk, L, Hugh E Montgomery, Mike PW Grocott, Imray, Christopher H. E., Wilson, M. H., Shashivadan P Hirani, Wilson, Mark H., Newman, SP, Montgomery, Hugh E., Edsell, MEG, Lisa Strycharczuk, Grocott, Mike P.W., Stanton P Newman, Mark H Wilson, Davagnanam, Indran, Caudwell Xtreme Everest Research Group, Levett, Denny Z.H., Imray, C. H. E., Edsell, M. E. G., Christopher HE Imray, Strycharczuk, Lisa, Grocott, Michael P. W., Levett, Denny Z. H., null null, Montgomery, H. E., Indran Davagnanam, John S Thornton, Grocott, M. P. W., Strycharczuk, L., Hirani, S. P., Grocott, MPW, Denny ZH Levett, Grocott, Mike P. W., Edsell, Mark E.G., Newman, S. P., Hirani, SP, Imray, Christopher H.E., Levett, D. Z. H., Wilson, MH, Xavier Golay, Newman, S. P. (Stanton P.), Davagnanam, I., Golay, X., Golay, X, Martin, D. S., Imray, CHE, Edsell, Mark E. G., Davagnanam, I, Montgomery, HE, Martin, DS, Thornton, J. S., Martin, Dan S., Thornton, John S., Levett, DZH, Dan S Martin, Thornton, JS, HASH(0x55a680246940), Newman, Stanton P.   +61 more
core   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Linear CT-scan measurements of cerebral ventricles in senile Poodle dogs. [PDF]

Braz J Vet Med, 2023
Araújo GVD, de Souza-Junior P, Viana-Peçanha S, Dos Santos-Sousa CA, Ramos MT, Bernardes FCS, Abidu-Figueiredo M.   +6 more
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Small Nucleus Accumbens and Large Cerebral Ventricles in Infants and Toddlers Prior to Receiving Diagnoses of Autism Spectrum Disorder. [PDF]

Cereb Cortex, 2022
Shiohama T, Ortug A, Warren JLA, Valli B, Levman J, Faja SK, Tsujimura K, Maunakea AK, Takahashi E.   +8 more
europepmc   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

The influence of size and progression of Intra-cerebral Hematoma on the Lateral Ventricles [PDF]

, 2019
Cerebrovascular diseases like intra cerebral hemorrhage are quite deadly and may disturb functioning of the brain, expanding and resulting in formation of an intra cerebral hematoma(ICH).
Ashraf, Muhammad J
core  

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

A novel ventriculoperitoneal shunt flow sensor based on electrically induced spatial variation in cerebrospinal fluid charge density

Frontiers in Bioengineering and Biotechnology
Introduction: Ventriculoperitoneal (VP) shunts divert cerebrospinal fluid (CSF) out of cerebral ventricles in patients with hydrocephalus or elevated intracranial pressure (ICP). Despite high failure rates, there exist limited clinically viable solutions
David A. Zarrin, Matiar Jafari, Won Kim, Geoffrey P. Colby   +3 more
doaj   +1 more source