Results 61 to 70 of about 14,702 (113)
Achievement of recommended glucose and blood pressure targets in patients with type 2 diabetes and hypertension in clinical practice -- study rationale and protocol of DIALOGUE [PDF]
, 2012 BACKGROUND: Patients with type 2 diabetes have 2–4 times greater risk for cardiovascular morbidity and mortality than those without, and this is even further aggravated if they also suffer from hypertension.
Anselm K Gitt +5 more
core +2 more sources
ApoE4 Homozygosity Is Associated With Increased Microglia Activation in Fatal COVID‐19
Neuropathology, Volume 45, Issue 6, December 2025.ABSTRACT Apolipoprotein E4 (APOE4) is recognized as a major risk factor for disorders such as Alzheimer's disease and may play a role in the dysregulation of microglia in various neurodegenerative conditions. APOE variants have also been proposed as potential risk factors for severe outcomes in COVID‐19.
Amar Hamdan +7 more
wiley +1 more source
Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives
Advanced Science, Volume 12, Issue 44, November 27, 2025.Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley +1 more source
残余代谢危险因素与青年卒中 Residual Metabolic Risk Factors and Stroke in Young Adults
Zhongguo cuzhong zazhi青年卒中一般指在18～50岁年龄段内发生的卒中，其发病率上升给我国带来了日益增加的社会经济负担。在探讨青年卒中的代谢危险因素时，除了传统的高血压、糖代谢异常、脂代谢异常和肥胖外，残余代谢危险因素亦不容忽视。本文重点关注了炎症、高同型半胱氨酸血症、高尿酸血症和肠道微生物群代谢产物这4种残余代谢危险因素对青年卒中的影响。炎症在青年卒中中的作用显著，与心源性脑栓塞这一重要病因的发生发展密切相关。高同型半胱氨酸血症通过影响血管内皮和凝血功能促进血栓形成，是有望预测卒中风险及预后的重要指标 ...
钱宇彤1，2，张书凡1，2，韩振翔3，吴维诚4，韩翔1，2 (QIAN Yutong1,2, ZHANG Shufan1,2, HAN Zhenxiang3, WU Weicheng4, HAN Xiang1,2 )
doaj +1 more source
The effects of hemodynamic lag on functional connectivity and behavior after stroke [PDF]
, 2015 Stroke disrupts the brain's vascular supply, not only within but also outside areas of infarction. We investigated temporal delays (lag) in resting state functional magnetic resonance imaging signals in 130 stroke patients scanned two weeks, three months
Corbetta, Maurizio +4 more
core +1 more source
Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.Abstract The establishment of brain banks is a strategic initiative to advance research on neurodegenerative diseases in Latin America. This article highlights the development, operations, and multidisciplinary framework of the National Dementia BioBank in Mexico and the National Brain Bank in the Dominican Republic. Both centers focus on the molecular
Nabil Itzi Luna‐Viramontes +12 more
wiley +1 more source
Preventive cytoprotection in social diseases
Терапевтический архив, 2015 Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov +4 more
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Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke with and without metabolic syndrome. [PDF]
, 2014 OBJECTIVE: The aim of our study was to evaluate the associations between arterial stiffness indexes and immune-inflammatory markers in subjects with acute ischemic stroke with and without metabolic syndrome.
Arnao, V. +10 more
core +2 more sources
Adverse Associations between Visceral Adiposity, Brain Structure, and Cognitive Performance in Healthy Elderly [PDF]
, 2011 The link between central adiposity and cognition has been established by indirect measures such as BMI or waist-hip ratio. Magnetic resonance imaging (MRI) quantification of central abdominal fat has been linked to elevated risk of cardio-vascular and ...
Vivian Isaac +5 more
core +1 more source
Revista Cubana de Investigaciones Biomédicas, 2012 La aterosclerosis es un proceso de origen multicausal y se acompaña de una gran variedad de manifestaciones clínicas y humorales. Son conocidos los factores de riesgo aterogénicos como dislipidemias, hipertensión arterial, diabetes mellitus, obesidad ...
Regino Piñeiro Lamas +2 more
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