Results 21 to 30 of about 246,541 (132)

The role of angiotensin II type 1 receptor pathway in cerebral ischemia‒reperfusion injury: Implications for the neuroprotective effect of ARBs. [PDF]

Neuroprotection
The performance of AT1R activation on ischemia–reperfusion injury. Abstract Cerebral ischemia–reperfusion (I/R) injury is a crucial factor that impacts the prognosis of recanalization therapy for acute ischemic stroke (AIS). It has been found that the brain renin–angiotensin system, especially the angiotensin II type 1 receptor (AT1R) pathway, plays a ...
Huang S, Zhang M.
europepmc   +2 more sources

Cell Death Mode Switch from Necrosis to Apoptosis in Brain [PDF]

, 2004
In brain ischemia, cell destructive necrosis occurs in the core, which in turn links to cell death expansion in the vicinity. Apoptosis, on the other hand, occurs in the surroundings of the core, called the penumbra, several days later.
Ueda, Hiroshi, Fujita, Ryousuke
core   +1 more source

Studies of autofluorescence in experimentally induced cerebral necrosis in pigs

, 1980
Lesions of cerebrocortical necrosis experimentally induced in pigs by transcalvarial freezing with liquid nitrogen were slightly fluorescent 48 hours after surgery.
P. B. Little, J. Y. S. Lee, Lee, J. Y., Little, P. B.   +3 more
core   +2 more sources

Infected Necrosis in Severe Pancreatitis - Combined Nonsurgical Multi-Drainage with Directed Transabdominal High-Volume Lavage in Critically Ill Patients [PDF]

, 2009
Background: Infection of pancreatic necrosis is a life-threatening complication during the course of acute pancreatitis. In critically ill patients, surgical or extended endoscopic interventions are associated with high morbidity and mortality. Minimally
Huber, W., Umgelter, A., Gaa, J., Prinz, C., Becker, V., Schmid, R. M., Bajbouj, M., Ludwig, L., Meining, Alexander, Becker, V.;Huber, W.;Meining, A.;Prinz, C.;Umgelter, A.;Ludwig, L.;Bajbouj, M.;Gaa, J.;Schmid, R. M., Becker, V;Huber, W;Meining, A;Prinz, C;Umgelter, A;Ludwig, L;Bajbouj, M;Gaa, J;Schmid, RM   +10 more
core   +1 more source

Welfare of cattle at slaughter

EFSA Journal, Volume 18, Issue 11, November 2020., 2020
Abstract The killing of cattle for human consumption (slaughtering) can take place in a slaughterhouse or on farm. The processes of slaughtering that were assessed for welfare, from the arrival of cattle until their death (including slaughtering without stunning), were grouped into three main phases: pre‐stunning (including arrival, unloading from the ...
EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Dominique Joseph Bicout, Paolo Calistri, Klaus Depner, Julian Ashley Drewe, Bruno Garin‐Bastuji, Jose Luis Gonzales Rojas, Christian Gortázar Schmidt, Virginie Michel, Miguel Ángel Miranda Chueca, Helen Clare Roberts, Liisa Helena Sihvonen, Hans Spoolder, Karl Stahl, Antonio Velarde, Arvo Viltrop, Denise Candiani, Yves Van der Stede, Christoph Winckler   +20 more
wiley   +1 more source

The cerebrovascular response to norepinephrine: A scoping systematic review of the animal and human literature

Pharmacology Research &Perspectives, Volume 8, Issue 5, October 2020., 2020
Abstract Intravenous norepinephrine (NE) is utilized commonly in critical care for cardiovascular support. NE’s impact on cerebrovasculature is unclear and may carry important implications during states of critical neurological illness. The aim of the study was to perform a scoping review of the literature on the cerebrovascular/cerebral blood flow ...
Logan Froese, Joshua Dian, Alwyn Gomez, Bertram Unger, Frederick A. Zeiler   +4 more
wiley   +1 more source

Downregulation of Tumor Necrosis Factor Expression in the Human Mono-Mac-6 Cell Line [PDF]

, 1989
Mono-Mac-6 cells, but not U937 cells, can be Induced to rapidly express tumor necrosis factor (TNF) mRNA and protein when triggered with Ilpopolysaccharlde (LPS) at 1 pg/mI. Preincubatlon of the cells for 3 d with low amounts of LPS (10 ng/mI) results In
Thiel, Corinna, Haas, Jürgen G., Ziegler-Heitbrock, H. W. Löms, Blömer, Kathi, Weiss, Elisabeth H., Riethmüller, Gert   +5 more
core   +1 more source

Left‐displaced abomasum in a late‐pregnant goat

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A female goat in late gestation was presented to a veterinary teaching hospital due to the sudden onset of abdominal distention and signs of cardiovascular depression. On admission, the goat exhibited an overloaded rumen, which seemed noticeably distant from the abdominal wall on the left‐hand side.
Eva Petzl, Katja Voigt, Viktoria Balasopoulou, Maria Beer, Florian M. Trefz   +4 more
wiley   +1 more source

Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high‐throughput RNA sequencing

British Journal of Pharmacology, Volume 182, Issue 16, Page 3800-3817, August 2025.
Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti, Valentin Varga, Erda Qorri, Rita Frank, Diana Kata, Krisztián Vinga, Péter Archibald Szarvas, Ákos Menyhárt, Károly Gulya, Ferenc Bari, Eszter Farkas   +10 more
wiley   +1 more source

Detection and measurement of necrosis in plants

, 2013
Necrosis plays a fundamental role in plant physiology and pathology. When plants or plant cell cultures are subjected to abiotic stress they initiate rapid cell death with necrotic morphology. Likewise, when plants are attacked by pathogens, they develop
Stålhandske, Lada,, Minina, Alyona,, Sveriges lantbruksuniversitet., Sanchez, Vera Victoria,, Daniel, Geoffrey,, Bozhkov, Peter,   +5 more
core   +1 more source