Results 1 to 10 of about 2,596,351 (209)

Cerebrospinal Fluid–Basic Concepts Review

Biomedicines, 2023
Cerebrospinal fluid plays a crucial role in protecting the central nervous system (CNS) by providing mechanical support, acting as a shock absorber, and transporting nutrients and waste products.
Natalia Czarniak, Joanna Kamińska, Joanna Matowicka-Karna, Olga Martyna Koper-Lenkiewicz   +3 more
doaj   +2 more sources

Case Report: Cerebrospinal fluid eosinophilia in adult autoimmune GFAP astrocytopathy [PDF]

Frontiers in Immunology
A 30-year-old Chinese male diagnosed with autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy presented with cerebrospinal fluid (CSF) eosinophilia.
Yuting Hou, Chunmei Zhao, Xu Wang
doaj   +2 more sources

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Nature Medicine, 2020
Erik C B Johnson, Eric B Dammer, Duc M Duong   +2 more
exaly   +2 more sources

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease

Nature, 2020
David Gate, Naresha Saligrama, Olivia Leventhal   +2 more
exaly   +2 more sources

Neopterin and CXCL-10 in Cerebrospinal Fluid as Potential Biomarkers of Neuroinvasive Dengue and Chikungunya

Pathogens, 2021
Dengue (DENV) and chikungunya viruses (CHIKV) cause severe neurological complications, sometimes undiagnosed. Therefore, the use of more accessible neuroinflammatory biomarkers can be advantageous considering their diagnostic and prognostic potential for
Marzia Puccioni-Sohler, Samya J. da Silva, Luiz C. S. Faria, David C. B. I. Cabral, Mauro J. Cabral-Castro   +4 more
doaj   +1 more source

Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels

Nature Neuroscience, 2022
It remains unclear how immune cells from skull bone marrow niches are recruited to the meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via dura–skull channels, and CSF proteins signal onto diverse cell types within the ...
J. Mazzitelli, Leon C. D. Smyth, Kevin A Cross, Taitea Dykstra, Jerry Sun, Siling Du, Tornike Mamuladze, Igor Smirnov, Justin Rustenhoven, J. Kipnis   +9 more
semanticscholar   +1 more source

Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum

JAMA Neurology, 2021
Key Points Question What are the levels of plasma glial fibrillary acidic protein (GFAP) throughout the Alzheimer disease (AD) continuum, and how do they compare with the levels of cerebrospinal fluid (CSF) GFAP?
A. Benedet, M. Milà-Alomà, Agathe Vrillon, N. Ashton, T. Pascoal, F. Lussier, T. Karikari, C. Hourrègue, E. Cognat, J. Dumurgier, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, Gemma Salvadó, M. Shekari, G. Operto, J. Gispert, C. Minguillón, K. Fauria, Gwendlyn Kollmorgen, I. Suridjan, E. Zimmer, H. Zetterberg, J. Molinuevo, C. Paquet, P. Rosa-Neto, K. Blennow, M. Suárez‐Calvet   +28 more
semanticscholar   +1 more source

Cerebrospinal Fluid Flow.

Annual Review of Fluid Mechanics, 2022
Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and through the brain transports not only those water-like fluids but also any solutes they carry, including nutrients, drugs, and metabolic wastes.
D. H. Kelley, John H. Thomas
semanticscholar   +1 more source

Cerebrospinal fluid type I interferon and cytokine profiles in enteroviral meningitis according to the presence or absence of pleocytosis

Pediatrics and Neonatology, 2021
Background: Enteroviral meningitis is typically diagnosed as the presence of pleocytosis and of viral RNA in cerebrospinal fluid. However, it was recently reported that more than 50% of infants with enteroviral meningitis diagnosed by polymerase chain ...
Kyung Yeon Lee, Jae Hee Seol, Chae Hyeon Yi, Won Hyeok Lee   +3 more
doaj   +1 more source

Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders

Fluids and Barriers of the CNS, 2022
Background Quantitative measurements of cerebrospinal fluid to blood clearance has previously not been established for neurological diseases. Possibly, variability in cerebrospinal fluid clearance may affect the underlying disease process and may ...
Markus Herberg Hovd, Espen Mariussen, Hilde Uggerud, Aslan Lashkarivand, Hege Christensen, Geir Ringstad, Per Kristian Eide   +6 more
doaj   +1 more source