Results 1 to 10 of about 526,129 (312)

Neurofilament light as a biomarker of axonal degeneration in patients with mild cognitive impairment and Alzheimer’s disease

open access: yesJournal of Integrative Neuroscience, 2021
Cerebrospinal fluid neurofilament light and plasma neurofilament light concentrations are elevated in patients with mild cognitive impairment and Alzheimer’s disease.
Yi Chen   +5 more
doaj   +1 more source

Spectrophotometry for cerebrospinal fluid pigment analysis [PDF]

open access: yes, 2006
The use of spectrophotometry for the analysis of the cerebrospinal fluid (CSF) is reviewed. The clinically relevant CSF pigments--oxyhemoglobin and bilirubin--are introduced and discussed with regard to clinical differential diagnosis and potentially ...
Keir, G., Petzold, A., Sharpe, L.T.
core   +1 more source

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]

open access: yes, 2016
BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea   +8 more
core   +1 more source

Top-cited articles in cerebrospinal fluid leak (rhinorrhea and otorrhea) (1945–2018)

open access: yesBrazilian Journal of Otorhinolaryngology, 2021
Introduction: As scientific knowledge has grown in biomedicine, it has also become necessary to develop tools to manage and understand the body of evidence.
Irene Monjas-Cánovas   +4 more
doaj   +1 more source

Subtotal petrosectomy and cerebrospinal fluid leakage in unilateral anacusis [PDF]

open access: yes, 2014
Objective This study presents a group of patients experiencing recurrent cerebrospinal fluid (CSF) leakage associated with ipsilateral anacusis who underwent subtotal petrosectomies with the goal of stopping the CSF leak and preventing meningitis ...
Iannella, Giannicola, Magliulo, Giuseppe
core   +1 more source

Drug transport in brain via the cerebrospinal fluid

open access: yesFluids and Barriers of the CNS, 2011
The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricles, as well as the cranial and spinal sub ...
Pardridge William M
doaj   +1 more source

Evaluation of microbial bacterial and fungal diversity in cerebrospinal fluid shunt infection. [PDF]

open access: yesPLoS ONE, 2014
Cerebrospinal fluid shunt infection can be recalcitrant. Recurrence is common despite appropriate therapy for the pathogens identified by culture. Improved diagnostic and therapeutic approaches are required, and culture-independent molecular approaches ...
Tamara D Simon   +8 more
doaj   +1 more source

Different intra-cerebrospinal distribution of linezolid in patients with inflammatory meningitis

open access: yesInternational Journal of Infectious Diseases, 2021
Linezolid has excellent antibiotic activity against gram-positive organisms and is expected to be an alternative to vancomycin for the treatment of bacterial meningitis.
Naoki Ichinose   +9 more
doaj   +1 more source

Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]

open access: yes, 2015
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca   +6 more
core   +2 more sources

Cerebrospinal Fluid Flow

open access: yesAnnual Review of Fluid Mechanics, 2023
Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and through the brain transports not only those water-like fluids but also any solutes they carry, including nutrients, drugs, and metabolic wastes. Passing through brain tissue primarily during sleep, this circulation has implications for neurodegenerative ...
Douglas H, Kelley, John H, Thomas
openaire   +2 more sources

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