Results 21 to 30 of about 1,800,537 (296)
Drug transport in brain via the cerebrospinal fluid
Fluids and Barriers of the CNS, 2011 The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricles, as well as the cranial and spinal sub ...Pardridge William Mdoaj +1 more sourceCerebrospinal Fluid Flow
Annual Review of Fluid Mechanics, 2023 Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and through the brain transports not only those water-like fluids but also any solutes they carry, including nutrients, drugs, and metabolic wastes. Passing through brain tissue primarily during sleep, this circulation has implications for neurodegenerative ...Douglas H, Kelley, John H, Thomasopenaire +2 more sourcesCerebrospinal Fluid Tau, p-Tau 181 and Amyloid-beta(38/40/42) in Frontotemporal Dementias and Primary Progressive Aphasias [PDF]
, 2010 Background/Aims: We determined cerebrospinal fluid (CSF) concentrations of amyloid-beta(A beta)(1-38), A beta(1-40), A beta(1-42), total tau and phospho-tau (p-tau) in order to study their differential expression in frontotemporal dementia (FTD, n = 25 ...Hermann Esselmann, Mirko Bibl, Johannes Kornhuber, Markus Otto, Esselmann, Hermann, Rüther, Eckart, Otto, Markus, Lewczuk, Piotr, Kornhuber, Johannes, Eckart Rüther, Piotr Lewczuk, Brit Mollenhauer, Bibl, Mirko, Wolf, Stefanie, Jens Wiltfang, Mollenhauer, Brit, Wiltfang, Jens, Stefanie Wolf, Esselmann, Hermann; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Wiltfang, Jens; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Mollenhauer, Brit; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Bibl, Mirko; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Rüther, Eckart; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Rüther, Echart, Wolf, Stefanie; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Lewczuk, Piotr; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Otto, Markus; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany, Kornhuber, Johannes; aDepartment of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, and bKlinik für Psychiatrie und Psychotherapie der Rheinischen Kliniken Essen, Universität Duisburg-Essen, Essen, cUniversity of Göttingen and Paracelsus-Elena Klinik, Kassel, dDepartment of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, eDepartment of Psychiatry, University of Göttingen, Göttingen, fInstitute for Neurology, University of Ulm, Ulm, and gDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilian-University of Munich, Munich, Germany +27 morecore +1 more sourceTau protein, A beta 42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies [PDF]
, 2005 The intra vitam diagnosis of dementia with Lewy bodies (DLB) is still based on clinical grounds. So far no technical investigations have been available to support this diagnosis.Cepek, L., Neumann, M., Ciesielczyk, Barbara, Cepek, Lukas, Neumann, Manuela, Trenkwalder, C., Kretzschmar, Hans A., Otto, M., Mollenhauer, B., Schulz-Schaeffer, W. J., Poser, Sigrid, Otto, Markus, Ciesielczyk, B., Steinacker, Petra, Steinacker, P., Wiltfang, J., Schulz-Schaeffer, Walter J., Poser, S., Bibl, Mirko, Mollenhauer, Brit, Trenkwalder, Claudia, Bibl, M., Wiltfang, Jens, Kretzschmar, H. A. +23 morecore +1 more sourceEvaluation of microbial bacterial and fungal diversity in cerebrospinal fluid shunt infection. [PDF]
PLoS ONE, 2014 Cerebrospinal fluid shunt infection can be recalcitrant. Recurrence is common despite appropriate therapy for the pathogens identified by culture. Improved diagnostic and therapeutic approaches are required, and culture-independent molecular approaches ...Tamara D Simon, Christopher E Pope, Samuel R Browd, Jeffrey G Ojemann, Jay Riva-Cambrin, Nicole Mayer-Hamblett, Margaret Rosenfeld, Danielle M Zerr, Lucas Hoffman +8 moredoaj +1 more sourceDifferent intra-cerebrospinal distribution of linezolid in patients with inflammatory meningitis
International Journal of Infectious Diseases, 2021 Linezolid has excellent antibiotic activity against gram-positive organisms and is expected to be an alternative to vancomycin for the treatment of bacterial meningitis.Naoki Ichinose, Gakushi Yoshikawa, Eri Fukao, Mai Ichisawa, Tomoaki Takahata, Yuki Enoki, Kazuaki Taguchi, Toshimi Oda, Kazuo Tsutsumi, Kazuaki Matsumoto +9 moredoaj +1 more sourceSerum heart-type fatty acid-binding protein and cerebrospinal fluid tau: Marker candidates for dementia with Lewy bodies [PDF]
, 2007 Background: The measurement of biomarkers in cerebrospinal fluid (CSF) has gained increasing acceptance in establishing the diagnosis of some neurodegenerative diseases.Steinacker, Petra, Brechlin, Peter, Bahn, Erik, Bibl, Mirko, Locascio, Joseph J., Kretzschmar, Hans A., Mollenhauer, Brit, Trenkwalder, Claudia, Schlossmacher, Michael G., Poser, Sigrid, Otto, Markus, Wiltfang, Jens +11 morecore +1 more source
