Results 91 to 100 of about 562,738 (359)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

CEREBROSPINAL FLUID ENZYMES

Zdravniški Vestnik, 2008
BACKGROUND Our goal was to determine the actual amount of lumbar punctures and spectrum of analyses, particularly on enzyme diagnostics, ordered at the University Clinical Center Mariborin year 2006.As the brain is very rich on glutamate dehydrogenaze ...
Matej Kravoš, Gregor Kralj, Ivan Malešič   +2 more
doaj  

High Level of Soluble CD146 In Cerebrospinal Fluid Might be a Biomarker of Severity of Anti-N-Methyl-D-Aspartate Receptor Encephalitis [PDF]

, 2021
Qing Li, Jinglong Chen, Mengzhuo Yin, Jun Zhao, Fuchang Lu, Zhanhang Wang, Xiaoqi Yu, Wang Shuang-yan, Zheng Dong, Honghao Wang   +9 more
openalex   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Plasma neuronal specific enolase : a potential stage diagnostic marker in human African trypanosomiasis [PDF]

, 2014
© The Author 2014. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Mitchell, Julia A, Sternberg, Jeremy M
core   +1 more source

Cerebrospinal fluid catecholamines in delirium and dementia [PDF]

, 2021
Kristi Henjum, Kristin Godang, Else Quist‐Paulsen, Ane‐Victoria Idland, Bjørn Erik Neerland, Heidi Vihovde Sandvig, Anniken Brugård, Johan Ræder, Frede Frihagen, Torgeir Bruun Wyller, Bjørnar Hassel, Jens Bollerslev, Leiv Otto Watne   +12 more
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Antibodies to Enteroviruses in Cerebrospinal Fluid of Patients with Acute Flaccid Myelitis. [PDF]

, 2019
Acute flaccid myelitis (AFM) has caused motor paralysis in >560 children in the United States since 2014. The temporal association of enterovirus (EV) outbreaks with increases in AFM cases and reports of fever, respiratory, or gastrointestinal illness
Briese, Thomas, Burns, Jane C, Caciula, Adrian, Garcia, Joel A, Hetzler, Kimbell L, Jain, Komal, Konopka-Anstadt, Jennifer L, Lipkin, W Ian, Marine, Rachel L, Mishra, Nischay, Ng, James, Ng, Terry Fei Fan, Nix, W Allan, Oberste, M Steven, Price, Adam, Routh, Janell A, Thakkar, Riddhi, Thakkar, Roshni, Thakur, Kiran T, Tokarz, Rafal   +19 more
core   +2 more sources

Genome-Wide Epistasis Study of Cerebrospinal Fluid Hyperphosphorylated Tau in ADNI Cohort [PDF]

, 2023
Dandan Chen, Jin Li, Hongwei Liu, Xiaolong Liu, Chenghao Zhang, Haoran Luo, Yiming Wei, Yang Xi, Hong Liang, Qiushi Zhang   +9 more
openalex   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source